...Roger Guillemin A short historical review is presented of the events leading to the discovery of somatostatin, an inhibitor of the secretion of growth hormone, while we were engaged in the search of a releasing factor for growth hormone. Also, of the early days of the recognition of the unexpected...

...H.P. Schedl; J. Schwartz; H.D. Wilson Depressed somatic growth in the rat with streptozotocin diabetes is associated with greatly enhanced intestinal growth. In patients with diabetes mellitus, growth hormone is elevated. Therefore, we measured the association between gut growth and serum growth...

...S. Raptis; H.C. Dollinger; L. von Berger; W. Schlegel; K.E. Schröder; E.F. Pfeiffer Somatostatin, a recently synthesized hypothalamic growth hormone release-inhibiting factor (GIF), was used in the cyclic and linear form. In all subjects studied, the cyclic GIF inhibited gastrin secretion during...