... AI systems for GI neoplasms, focusing on esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cancer (GC), and colorectal polyps. In ESCC and EAC, computer-aided detection (CADe) systems were mainly developed, and a recent meta-analysis study showed sensitivities...

... hallmark of early gastric cancer (EGC) with poor prognosis. However, the molecular mechanism of the progression from intramucosal gastric cancer (IMGC) to early submucosal-invasive gastric cancer (SMGC) is not fully understood. The objective of this study was to identify genes and pathways involved...

... Nishisaki; Takashi Toyonaga; Yuzo Kodama Introduction: Favorable long-term outcomes of endoscopic submucosal dissection (ESD) for early remnant gastric cancer (ERGC) have been reported in single-center studies from advanced institutions. However, no studies have examined the long-term outcomes using...

... Sugimoto; Yoshiya Yamauchi; Shin Kono; Sakiko Naito Introduction: As the high mortality rate of gastric cancer (GC) is due to delayed diagnosis, early detection is vital for improved patient outcomes. Metabolic deregulation plays an important role in GC. Although various metabolite-level biomarkers...

...Nobuhiro Nakazawa; Makoto Sohda; Arisa Yamaguchi; Takayoshi Watanabe; Hideyuki Saito; Yasunari Ubukata; Kengo Kuriyama; Akihiko Sano; Makoto Sakai; Hiroomi Ogawa; Ken Shirabe; Hiroshi Saeki Introduction: We evaluated the risk factors for patients with gastric cancer (GC) undergoing total...

...; Mitsuru Kaise; Katsuhiko Iwakiri Background and Aims: Surgery is recommended in early gastric cancer (EGC) after noncurative endoscopic submucosal dissection (ESD), although observation can be an alternative. We aimed to develop a tailor-made treatment strategy for noncurative EGCs by comparing the lymph...

... risk of gastric cancer (GC). With the increasing success of HP infection treatment, a larger number of GCs that develop after eradication can be assessed. Several studies have shown that epithelium with low-grade atypia (ELA) is a frequent characteristic of these GCs, but the origin of this condition...

...Satoki Shichijo; Noriya Uedo; Tomoki Michida Background: Based on evidence that Helicobacter pylori eradication reduces the development of gastric cancer and other diseases such as peptic ulcer, eradication therapy has prevailed. However, gastric cancer can develop even after successful eradication...

...Hiroyuki Abe; Tetsuo Ushiku Background: The prevalence of Helicobacter pylori infection and chronic atrophic gastritis is decreasing in Japan, which has led to a decline in the incidence of gastric cancer. However, there are various subtypes of gastric cancer that arise from the background mucosa...

...Masau Sekiguchi; Ichiro Oda; Takahisa Matsuda; Yutaka Saito Background: The global epidemiological situation of gastric cancer has changed considerably over time, and it is essential to understand the epidemiological trends and future perspectives of gastric cancer. Summary: Although gastric cancer...

...Mitsuko Inuyama; Yusuke Horiuchi; Noriko Yamamoto; Shoichi Yoshimizu; Akiyoshi Ishiyama; Toshiyuki Yoshio; Toshiaki Hirasawa; Tomohiro Tsuchida; Yoshinori Igarashi; Junko Fujisaki Introduction: Curative rates of endoscopic treatment for undifferentiated-type early gastric cancer (EGC), particularly...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Carboxymethylcellulose Endoscopic resection Endoscopic submucosal dissection Gastric cancer Injectant Endoscopic submucosal dissection (ESD) for early...

...Genki Usui; Keisuke Matsusaka; Yasunobu Mano; Masayuki Urabe; Sayaka Funata; Masashi Fukayama; Tetsuo Ushiku; Atsushi Kaneda Background: Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide. GC is a pathologically and molecularly heterogeneous disease. DNA...

...: gastric cancer (GC) cohort, 183 patients (90 healthy controls (HCs) and 93 GC patients); esophageal cancer (EC) cohort, 115 patients (90 HCs and 25 EC patients); and colorectal cancer (CRC) cohort, 188 patients (92 HCs and 96 CRC patients) after age- and sex matching using the propensity score...

...Minami Hashimoto; Takuto Hikichi; Jun Nakamura; Ko Watanabe; Mika Takasumi; Tsunetaka Kato; Rei Suzuki; Mitsuru Sugimoto; Hiroki Irie; Tadayuki Takagi; Hiromasa Ohira Introduction: In patients with intramucosal gastric cancer (MGC) who have undergone endoscopic submucosal dissection (ESD...

...Hitomi Kikuchi; Takuto Hikichi; Ko Watanabe; Jun Nakamura; Minami Hashimoto; Tsunetaka Kato; Katsutoshi Obara; Hiromasa Ohira Introduction: Although L-menthol spray application on lesions has been shown to be effective for the endoscopic clarification of early gastric cancer (EGC), the currently...

... to evaluate the effect of implementing antithrombotic agent management guidelines (GL-2012) on postoperative bleeding after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) and on the prevention of thromboembolic events. Methods: A total of 1,264 patients who underwent ESD for EGC...

...Kosaku Hata; Masanori Ito; Tomoyuki Boda; Takahiro Kotachi; Mariko Kiso; Kazuhiko Masuda; Mio Kurihara; Kazutaka Kuroki; Naoki Yorita; Naoko Nagasaki; Madina Abduwali; Shinji Tanaka; Kazuaki Chayama Background and Aim: The incidence of gastric cancer occurring after successful Helicobacter pylori...

...Yoshishiro Hiramatsu; Hiroya Takeuchi; Osamu Goto; Hirotoshi Kikuchi; Yuko Kitagawa Background: Recently, minimally invasive approaches such as endoscopic treatment or laparoscopic gastrectomy for early gastric cancer have made rapid progress. However, the extent of gastrectomy and lymphadenectomy...

... retrospective study evaluated 237 patients with early gastric cancer: 83 who underwent ESD using the CC group and 154 who underwent ESD using the insulated-tip knife 2 (IT2 group). Clinicopathological features and technical outcomes were compared between the 2 groups using a propensity score-matched analysis...