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Keywords: Famotidine
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Journal Articles
Subject Area:
Gastroenterology
Mariko Hojo, Akihito Nagahara, Daisuke Asaoka, Tsutomu Takeda, Kentaro Izumi, Kohei Matsumoto, Hiroya Ueyama, Yuji Shimada, Kenshi Matsumoto, Shuko Nojiri, Sumio Watanabe
Journal:
Digestion
Digestion (2017) 96 (1): 5–12.
Published Online: 13 June 2017
... syndrome (PDS). However, a treatment for FD patients with PDS and/or epigastric pain syndrome (EPS) has not been established. We investigated the efficacy of famotidine in combination with acotiamide for FD. Methods: Fifty blindly randomized FD patients received placebo with acotiamide, or famotidine...
Journal Articles
Subject Area:
Gastroenterology
Mitsushige Sugimoto, Masafumi Nishino, Chise Kodaira, Mihoko Yamade, Takahiro Uotani, Mutsuhiro Ikuma, Takahisa Furuta
Journal:
Digestion
Digestion (2012) 85 (1): 9–17.
Published Online: 24 November 2011
... only once daily, 100 mg aspirin + 20 mg famotidine twice daily, 15 mg lansoprazole once daily, or 10 mg rabeprazole once daily. All subjects underwent endoscopy and intragastric pH monitoring on day 7. Results: 7 individuals (46.7%) developed esophageal mucosal injury when ingesting aspirin alone...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1995) 56 (Suppl. 1): 51–60.
Published Online: 05 February 2009
..., esophageal Reflux esophagitis Barrett s (columnar-lined) esophagus Famotidine Antireflux surgery Abstract All the epithelia lining the gastrointestinal (GI) tract, including that of the esophagus, exhibit a transmucosal electrical potential difference (PD). The luminal surface of the GI mucosa is indeed...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1995) 56 (2): 145–152.
Published Online: 05 February 2009
.... Famotidine and indomethacin pretreatment only partially counteracted the MHA effect. The results indicate that MHA is highly effective in preventing ethanol-induced lesions but the exact mechanism is still uncertain. 27 12 1993 11 04 1994 1 07 1995 Original Paper Digestion 1995;56:145-152...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1989) 44 (Suppl. 1): 54–62.
Published Online: 03 February 2009
.... 1989 Gastro-oesophageal reflux disease Reflux oesophagitis H2-receptor antagonist Cimetidine Ranitidine Famotidine Nizatidine Cisapride Sucralfate Omeprazole Treatment Digestion I989;44(suppl i): 54-62 © 1989 S. Kargcr AG. Basel 0012-282.V89/0447-0054$2.75/0 Management of Gastro...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1988) 39 (3): 156–161.
Published Online: 30 January 2009
...Heinz Hartmann; Ulrich R. Fölsch The efficacy of famotidine, a potent new long-acting H 2 receptor antagonist, was compared with cimetidine in 78 patients with endoscopically proven acute duodenal ulcers. Additional antacid self-medication was allowed if needed for relief of pain. Thirty-nine...
Journal Articles
Subject Area:
Gastroenterology
Vincenzo Savarino, Giuseppe Sandro Mela, Patrizia Scalabrini, Ezio Di Timoteo, Maria Rita Magnolia, Guido Celle
Journal:
Digestion
Digestion (1987) 37 (2): 103–109.
Published Online: 30 January 2009
...Vincenzo Savarino; Giuseppe Sandro Mela; Patrizia Scalabrini; Ezio Di Timoteo; Maria Rita Magnolia; Guido Celle In 11 duodenal ulcer patients, the antisecretory effects of bedtime famotidine 40 mg were compared to those obtained with ranitidine 300 mg and placebo by means of continuous 24-hour...
Journal Articles
Subject Area:
Gastroenterology
Vincenzo Savarino, Giuseppe Sandro Mela, Patrizia Zentilin, Patrizia Scalabrini, Giuseppe Bonifacino, Patrizia Gambaro, Guido Celle
Journal:
Digestion
Digestion (1989) 42 (1): 1–6.
Published Online: 30 January 2009
...Vincenzo Savarino; Giuseppe Sandro Mela; Patrizia Zentilin; Patrizia Scalabrini; Giuseppe Bonifacino; Patrizia Gambaro; Guido Celle The effects of single daily doses of placebo, nizatidine 300 mg, ranitidine 300 mg and famotidine 40 mg, given at 22.00 h, have been compared in 16 patients...
Journal Articles
Subject Area:
Gastroenterology
L. Rodrigo, J. Viver, F. Conchillo, E. Barrio, M. Forné, J.M. Zozaya, A. Alvarez, P. Dieguez, M. Muñoz, J. Panés, J. Jiménez, R. Ruiz-Capellán
Journal:
Digestion
Digestion (1989) 42 (2): 86–92.
Published Online: 30 January 2009
...L. Rodrigo; J. Viver; F. Conchillo; E. Barrio; M. Forné; J.M. Zozaya; A. Alvarez; P. Dieguez; M. Muñoz; J. Panés; J. Jiménez; R. Ruiz-Capellán The efficacy and safety of famotidine (40 mg at night), a new potent H 2 -receptor antagonist, has been studied in 119 patients by four investigators...
Journal Articles
Subject Area:
Gastroenterology
R. Alcalá-Santaella, J. Guardia, J. Pajares, J. Piqué, L. Pita, E. Alvárez, P. Castellanos, L. Guarner, J. Ortiz, R. Pesquera, V. Vargas, R. Ruiz-Capellán
Journal:
Digestion
Digestion (1989) 42 (2): 79–85.
Published Online: 30 January 2009
...R. Alcalá-Santaella; J. Guardia; J. Pajares; J. Piqué; L. Pita; E. Alvárez; P. Castellanos; L. Guarner; J. Ortiz; R. Pesquera; V. Vargas; R. Ruiz-Capellán The efficacy and safety of famotidine and ranitidine in the treatment of active duodenal ulcer were compared in a multicenter, randomized double...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 62–69.
Published Online: 29 January 2009
...Gabriele Bianchi Porro The new H 2 receptor antagonist, famotidine, has been tested in open and double-blind studies in over 2,000 acute duodenal or gastric ulcer patients as well as in the maintenance of chronic duodenal ulcer patients. In early studies, dosages of 20 mg b.i.d. were found...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 45–50.
Published Online: 29 January 2009
...H.G. Dammann; T.A. Walter; E. Hentschel; P. Müller; B. Simon We conducted an 8-week, double-blind, randomized, placebo-controlled multicenter trial (Austria and Germany) to determine whether famotidine would speed healing or relief of symptoms in patients with benign gastric ulcer. Of the 65...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 59–61.
Published Online: 29 January 2009
...J.M. Howard; M.J. Collen; K.E. McArthur; J.A. Cherner; P.N. Maton; J.D. Gardner; R.T. Jensen The safety and efficacy of the new, highly potent histamine H 2 receptor antagonist, famotidine, was evaluated in nine patients with Zollinger-Ellison syndrome. Famotidine was found to be safe and effective...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 7–14.
Published Online: 29 January 2009
...J.D. Burek; J.A. Majka; D.L. Bokelman Extensive preclinical safety studies with famotidine were performed or sponsored by Yamanouchi Phamaceutical Co, Ltd, Tokyo, Japan, and Merck, Sharp & Dohme Research Laboratories, West Point, Pennsylvania, USA. These studies were performed in dogs, rats...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 15–23.
Published Online: 29 January 2009
...Lacey Smith The results of the initial clinical pharmacology studies of famotidine, a new H 2 receptor antagonist, are summarized. These studies indicate that: (1) single oral doses of famotidine (5–80 mg) were well tolerated; (2) famotidine effectively suppressed basal, nocturnal, pentagastrin...
Journal Articles
Subject Area:
Gastroenterology
B. Simon, H.G. Dammann, G. Jakob, S.E. Miederer, P. Müller, R. Ottenjann, F. Paul, T. Scholten, E. Schütz, E. Seifert, O. Stadelmann
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 32–37.
Published Online: 29 January 2009
... famotidine 40 mg once at night, 20 mg twice daily, 40 mg twice daily, or ranitidine 150 mg twice daily for 2 – 8 weeks. Pretreatment characteristics between the four groups were similar. After 4 weeks of treatment, among the famotidine-treated patients, 38 of 42 (90.5%) healed with the 40 mg once nightly...
Journal Articles
Subject Area:
Gastroenterology
L. Barbara, R. Corinaldesi, G. Bianchi Porro, M. Lazzaroni, A. Blasi, A. Mangiameli, L. Carratelli, A. Wilkins, R. Cheli, E. Bovero, P.R. Dal Monte, N. D’Imperio, A. Francavilla, F. Scotto, G. Mazzacca, F. Sabbatini, A. Torsoli, P. Paoluzi, G. Verme, V. Ponti, V. Speranza, E. Lezoche, A. Baglioni, F. Carotenuto, P.F. Matarazzo, F. Toti, V. Vagni
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 24–31.
Published Online: 29 January 2009
...; F. Carotenuto; P.F. Matarazzo; F. Toti; V. Vagni A multicenter study that involved 15 Italian institutions was carried out to compare the efficacy and safety of famotidine 40 mg at bedtime, famotidine 20 mg b.i.d., famotidine 40 mg b.i.d., and ranitidine 150 mg b.i.d. in promoting the healing...
Journal Articles
Subject Area:
Gastroenterology
P. Paoluzi, A. Torsoli, G. Bianchi Porro, M. Lazzaroni, L. Barbara, R. Corinaldesi, A. Blasi, A. Mangiameli, L. Carratelli, R. Cheli, E. Bovero, P.R. Dal Monte, N. D’Imperio, A. Francavilla, F. Doronzo, G. Mazzacca, F. Sabbatini, G. Verme, V. Ponti, V. Speranza, E. Lezoche, A. Baglioni, F. Carotenuto, P.F. Matarazzo
Journal:
Digestion
Digestion (1985) 32 (Suppl. 1): 38–44.
Published Online: 29 January 2009
.... Carotenuto; P.F. Matarazzo The aim of the present investigation was to study the efficacy and safety of famotidine (MK-208), a new, potent, histamine H 2 receptor antagonist, in promoting the healing of active gastric ulcer when compared to placebo. Of the 71 patients who took part in this multicenter double...
Journal Articles
Subject Area:
Gastroenterology
Yasushi Fukushima, Takashi Ishikawa, Toshihito Saitoh, Keisuke Tateishi, Takehide Ogihara, Midori Fujishiro, Nobuhiro Shojima, Miho Honda, Akifumi Kushiyama, Motonobu Anai, Hideyuki Sakoda, Hiraku Ono, Yukiko Onishi, Hiroko Otsuka, Hideki Katagiri, Ryozo Nagai, Masao Omata, Tomoichiro Asano
Journal:
Digestion
Digestion (2003) 68 (2-3): 145–152.
Published Online: 16 January 2004
... of action. This study aims to characterize how rapidly famotidine and ranitidine, the most widely used histamine H 2 receptor antagonists, interact with the human histamine H 2 receptor. Methods: HEK293 cell lines, stably expressing human histamine H 2 receptors, were obtained. The dose- and time-dependent...
Journal Articles
Subject Area:
Gastroenterology
Yasushi Fukushima, Hiroko Otsuka, Minako Ishikawa, Tomoichiro Asano, Motonobu Anai, Takao Katsube, Kenji Ogawa, Tetsuro Kajiwara, Shinichiro Ohkawa, Takashi Ishikawa, Masao Omata, Toshihito Saitoh
Journal:
Digestion
Digestion (2001) 64 (3): 155–160.
Published Online: 21 December 2001
... expressing human H 2 Rs were obtained. The dose-dependent effects of lafutidine and famotidine on [ 3 H]tiotidine binding and histamine-stimulated cAMP production were analyzed. The effects of preincubation with 2.78 × 10 –7 M of lafutidine or famotidine for 30 min on histamine-dependent cAMP production...