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1-20 of 21
Keywords: Epidermal growth factor
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Journal Articles
Subject Area:
Gastroenterology
Yasuhiro Fujiwara, Frederic Wyle, Tetsuo Arakawa, Matthew J. Domek, Takashi Fukuda, Kenzo Kobayashi, Andrzej Tarnawski
Journal:
Digestion
Digestion (1997) 58 (3): 299–303.
Published Online: 05 February 2009
... pylori and/or the interference of H pylori with ulcer healing are unknown. Through binding to its receptor, epidermal growth factor (EGF) accelerates cells migration and triggers epithelial cell proliferation which are both important for the healing of gastroduodenal ulcers. H pylori seems to interfere...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1996) 57 (5): 362–367.
Published Online: 05 February 2009
...R.J. Playford; R. Boulton; M.A. Ghatei; S.R. Bloom; N.A. Wright; R.A. Goodlad Epidermal growth factor (EGF) and transforming growth factor α (TGFα) bind to a common receptor and are both present in the normal gastrointestinal tract. Although many studies have examined their function in isolation...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1997) 58 (1): 28–33.
Published Online: 05 February 2009
... on the cell surface on day 18. In contrast, histamine (0.1-100 μ M ), carbachol (0.1-100 μ M ), gastrin-17 (0.1-100n M ), epidermal growth factor (0.01-10 ng/ ml; 1.7-1,700 p M ), transforming growth factor-α (0.01-10 ng/ml; 1.8-1,800 p M ), and fetal bovine serum (1-10%) did not increase glycoconjugate...
Journal Articles
Subject Area:
Gastroenterology
Tomasz Brzozowski, Stanislaw J. Konturek, Zbigniew Sliwowski, Robert Pajdo, Danuta Drozdowicz, Jerzy Stachura
Journal:
Digestion
Digestion (1997) 58 (4): 319–331.
Published Online: 05 February 2009
... mg/kg i.g.), β-adrenoceptor agonist, reduced dose-dependently ethanol-induced mucosal injury and this effect was accompanied by an elevation of the GBF similarly as after epidermal growth factor (EGF) (100 μg/kg·h s.c.) or after classic protective agent, 16,16-dimethyl-PGE 2 (PGE 2 ) (10 μg/kg i.g...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1994) 55 (2): 108–114.
Published Online: 05 February 2009
...Hajime Kuwayama; Takako Naito; Yoshio Kojima The effect of human epidermal growth factor (hEGF) on gastric epithelial proliferation was studied in vitro and in vivo. In the first study, subconfluent gastric epithelial cells derived from fetal rabbit stomach were incubated with hEGF at doses...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1992) 51 (1): 37–41.
Published Online: 04 February 2009
...Renato Zandomeneghi; Luca Serra; Chiara Pavesi; Ulrich Baumgartl; Cristina Poppi; Paolo Montanari The aim of the present study was to determine the effect of aspirin and indomethacin on epidermal growth factor (EGF) secretion in duodenal tissue fragments cultivated in vitro. The fragments were...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1991) 50 (1): 7–15.
Published Online: 04 February 2009
... epithelial cells were isolated and counted. Gastric mucous epithelial cells were enriched from the total gastric fundic cell population and cultured for 6 days in the absence or presence of hormones (epidermal growth factor and pentagastrin). We found that omeprazole treatment for 1–6 weeks significantly (p...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1990) 45 (4): 202–211.
Published Online: 03 February 2009
...S.J. Konturek; J. Tasler; W. Bielanski; M. Cieszkowski; W. Pawlik Epidermal growth factor (EGF) is widely distributed in the gastrointestinal tissues and released into the gut lumen but its physiological role is questionable because of the postulated high uptake and degradation of this peptide...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1991) 48 (3): 157–162.
Published Online: 03 February 2009
...Antoni Dyduch The effects of epidermal growth factor (EGF) on disaccharidase activity in intestinal epithelial cells were studied in mice. In salivectomised mice, the sucrase and maltase activities decreased significantly compared to the control group. When EGF was given to salivectomised mice...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1990) 46 (Suppl. 2): 92–98.
Published Online: 03 February 2009
.... 1990 Gastrointestinal hormones Hormone receptors Steroid hormones Carcinomas Colon Pancreas Stomach Epidermal growth factor Transforming growth factor α Digestion I990;46(suppl 2):92-98 © 1990 S. Karger A G , Basel 0012-2823/90/0468-0092S2.75/0 Hormones and Receptors...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1990) 47 (4): 181–190.
Published Online: 03 February 2009
...B.L. Slomiany; J. Liu; P. Yao; C.Y. Wu-Wang; J.P. Keogh; S.L. Wang; A. Slomiany The effects of epidermal growth factor (EGF), a potent mitogen involved in mucosal protection, are mediated by specific cellular receptors. Here, we present the characteristics and binding properties of EGF receptors...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1988) 41 (3): 121–128.
Published Online: 30 January 2009
... and the tissue contents of epidermal growth factor (EGF) in salivary glands, duodenum and pancreas, suggesting that both gastrin and EGF could contribute to mucosal trophic and ulcer healing effects of GRF. Somatostatin (100μg/kg/day for 7 days) abolished almost completely the ulcer healing and mucosal growth...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1989) 42 (3): 135–142.
Published Online: 30 January 2009
... and synthetic human epidermal growth factor (EGF) on angiogenesis and ulcer healing were investigated. The newly formed granulation vessels in the ulcer base were measured by means of a carmine dye infusion method. Prednisolone, administered subcutaneously at 40 mg/kg/day, significantly decreased angiogenesis...
Journal Articles
Subject Area:
Gastroenterology
Masatsugu Okuyama, Yasuhiro Fujiwara, Tetsuya Tanigawa, Kenji Watanabe, Masatsugu Shiba, Kazunari Tominaga, Toshio Watanabe, Nobuhide Oshitani, Kazuhide Higuchi, Tetsuo Arakawa
Journal:
Digestion
Digestion (2007) 75 (2-3): 135–141.
Published Online: 31 July 2007
... epithelial integrity. We examined the roles of ZO-1 and epidermal growth factor (EGF) in esophageal epithelial defense against acid using human esophageal epithelial cells. Methods: Human esophageal epithelial cells (TE-1) were incubated with acidified medium in the presence or absence of various doses...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (2004) 69 (4): 219–224.
Published Online: 09 August 2004
...Woo Sung Moon; Kenneth J. Chang; Adhip P.N. Majumdar; Andrzej S. Tarnawski Background/Aims: The mitogenic signaling pathway of epidermal growth factor receptor (EGFR) is activated in a variety of cancers, including hepatocellular carcinoma (HCC). The recently cloned EGFR-related protein (ERRP) has...
Journal Articles
Subject Area:
Gastroenterology
Tomasz Brzozowski, Peter C. Konturek, Stanislaw J. Konturek, Detlef Schuppan, Danuta Drozdowicz, Slawomir Kwiecień, Jolanta Majka, Tosikazu Nakamura, Eckhart G. Hahn
Journal:
Digestion
Digestion (2001) 64 (1): 15–29.
Published Online: 10 September 2001
...Tomasz Brzozowski; Peter C. Konturek; Stanislaw J. Konturek; Detlef Schuppan; Danuta Drozdowicz; Slawomir Kwiecień; Jolanta Majka; Tosikazu Nakamura; Eckhart G. Hahn Background/Aims: Ulcer healing involves expression of various growth factors such as epidermal growth factor (EGF), hepatocyte growth...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (2000) 61 (4): 230–236.
Published Online: 16 June 2000
... of the intestinal mucosa is high, and it occurs both by enhanced synthesis and by increased uptake from the lumen. Aims: To study mitogen-induced polyamine accumulation in the gut, we treated proliferating Caco-2 cells with epidermal growth factor (EGF) and measured the activity of ornithine decarboxylase (ODC...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1999) 60 (5): 461–468.
Published Online: 25 August 1999
.... This action may be through the change in apoptosis in the stomach. The aim of this study was to examine the effect of cigarette smoking on apoptosis in the gastric mucosa and the possible role of epidermal growth factor (EGF) in this action. Methods: Gastric blood flow was assessed by the laser Doppler...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestion
Digestion (1999) 60 (4): 314–323.
Published Online: 24 June 1999
...Zygmunt Warzecha; Artur Dembinski; Peter Ch. Konturek; Piotr Ceranowicz; Stanislaw J. Konturek Epidermal growth factor (EGF) exhibits gastroprotective and ulcer-healing action. These observations prompted us to determine the influence of EGF on cerulein-induced pancreatitis (CIP) in the rat. Acute...
Journal Articles
Subject Area:
Gastroenterology
Peter Ch. Konturek, Artur Dembinski, Zygmunt Warzecha, Astrid Ihlm, Piotr Ceranowicz, Stanislaw J. Konturek, Jerzy Stachura, Eckhart G. Hahn
Journal:
Digestion
Digestion (1998) 59 (2): 110–119.
Published Online: 02 April 1998
... and remodeling but the contribution of epidermal growth factor (EGF), that is well known to promote cell growth and regeneration, has not been investigated. The aim of this study was to compare the gene and immunohistochemical expression of EGF and TGF-β 1 , cell proliferation, and biochemical parameters in AP...
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