... (IGFBP). Colorectal cancers (CRCs) are heterogeneous, with left- and right-sided CRCs, showing different clinical and molecular characteristics. This case-control study, nested in the Japan Collaborative Cohort study, assessed associations between serum levels of IGF-related molecules and incidences...

...Takahisa Matsuda; Ai Fujimoto; Yoshinori Igarashi Background: Colorectal cancer (CRC) is a significant global health issue, ranking as the third most commonly diagnosed cancer and the second leading cause of cancer-related deaths. Countries with a high Human Development Index (HDI) report...

...Naoya Tada; Naoto Tamai; Kazuki Sumiyama Background: Colorectal cancer (CRC) is a major concern because of its increasing incidence and mortality worldwide. Therefore, effective screening strategies are necessary to reduce its incidence. Summary: In addition to fecal immunochemical tests...

... visual tasks, reaching high performance and thereby potentially supporting and even outperforming human experts. This is in particular relevant for colorectal cancer (CRC), which is the 3rd most common cancer type in general, as along the CRC patient journey many complex visual tasks need to be performed...

... Progressive nutritional index Postoperative chemotherapy Colorectal cancer Outcome What Does This Paper Add to the Literature? The benefit of adjuvant chemotherapy for locally advanced rectal cancer treated with preoperative chemoradiotherapy has not been revealed yet. The present study...

... in patients with invasive colorectal cancer (CRC) in a multinational study for comprehending the adenoma-carcinoma and serrated pathway about the development of CRC. Methods: We retrospectively reviewed 3,050 patients enrolled in the international randomized controlled trial (ATLAS study) to evaluate...

...Kenji Yamauchi; Tomoki Inaba; Takeshi Morimoto; Yusuke Aya; Hugh Shunsuke Colvin; Teruya Nagahara; Shigenao Ishikawa; Masaki Wato; Atsushi Imagawa Introduction: Non-curative endoscopic resection of T1 colorectal cancer (CRC) carries a substantial risk of recurrence. However, previous studies have...

...Thomas J. Lux; Katja Herold; Ioannis Kafetzis; Phillip Sodmann; Zita Sassmanshausen; Alexander Meining; Alexander Hann Introduction: Comprehensive and standardized colonoscopy reports are crucial in colorectal cancer prevention, monitoring, and research. This study investigates adherence...

...Hiroyuki Hisada; Yosuke Tsuji; Rina Cho; Yuko Miura; Hiroya Mizutani; Daisuke Ohki; Seiichi Yakabi; Yu Takahashi; Yoshiki Sakaguchi; Naomi Kakushima; Nobutake Yamamichi; Mitsuhiro Fujishiro Introduction: Colorectal cancer is a public health concern associated with high incidence rates. Sarcopenia...

...Zhanbo Qu; Jian Chu; Yinhang Wu; Jing Zhuang; Jiang Liu; Shugao Han; Wei Wu; Shuwen Han Introduction: Endoplasmic reticulum stress (ERS) is associated with the occurrence and development of colorectal cancer (CRC). Methods: One thousand nine CRC samples and 3 ERS gene sets from GEO database were...

... Carla Tablante; Varayu Prachayakul; Shinji Tanaka; The International Gastrointestinal Consensus Symposium Study Group Introduction: Diagnostic and therapeutic methods for colorectal cancer (CRC) have advanced; however, they may be inaccessible worldwide, and their widespread use is challenging...

... Katsumata; Kazuhiro Sakamoto Introduction: Regorafenib is a multi-kinase inhibitor approved for patients with metastatic colorectal cancer (mCRC) who were previously treated with standard therapies. A few reports showed the impact of KRAS mutation on therapeutic efficacy of regorafenib. Only one study...

...Yuejun Fang; Xiaoan Zhan Introduction: Colorectal cancer (CRC) is a common cancer. As metastasis and recurrence are main causes of CRC death, it is of great significance to find prognostic biomarkers. Methods: Data related to CRC were collected from GEO database. The patients were grouped based...

... are reported to be associated with colorectal cancer (CRC). However, their relationship and whether they cause CRC or are just adapted to the cancerous environment is not known. We approached this subject by investigating the correlation and distribution of the bacteria throughout the colon in patients...

...Jan Keck; Jochen Gaedcke; Michael Ghadimi; Thomas Lorf Background: Liver metastases (LM) occur in about 50% of patients with colorectal cancer. Besides the multimodal treatment of the primary tumor, the only way to cure patients with colorectal LM (CRLM) is complete resection. Different surgical...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Colorectal cancer Total neoadjuvant therapy Rectum The current therapy of rectal cancer patients has diversified toward risk-adapted approaches according to precise...

...Xingyun Zhan; Fenghua Bai; Sifeng Lin; Tao Feng; Xiaosi Tang; Yipeng Ding; Tianbo Jin Background: Colorectal cancer (CRC) is one of the common malignant tumors, with high mortality and poor prognosis. Our study aimed to determine the association between the long noncoding RNA (LncRNA) C5orf66...

... samples from patients with colorectal cancer (CRC), suggesting their involvement in the development of CRC. The aim of this study was to identify microbes which are increased in distal CRCs and to identify the specific location of microbes increased in mucosal tissue around the tumor. Methods: Tissue...

... colorectal cancer (EOCRC). The development of EOCRC may be associated with microbiota dysbiosis either dependently or independently (combined with other risk factors). Summary: Recently, the rising of incidence and mortality of EOCRC have been noted. Some researchers are looking for risk factors influencing...

..., instructions or products referred to in the content or advertisements. 2021 Multiple primary malignancies Multiple cancers Colorectal cancer Prognosis Colorectal cancer (CRC) is the third most common malignant disease worldwide and the second most common cause of cancer mortality [ 1...