... ‘sinusoidal’ [Ca 2+ ] i oscillations (when stimulated with muscarinic agonists) and so-called ‘baseline [Ca 2+ ] i spiking’ (when stimulated with cholecystokinin, bombesin or analogues of either peptide). These agonist-evoked [Ca 2+ ] i oscillations present novel problems to the investigator, particularly...

... compartments. Here, we focus on mechanisms by which the pancreatic acinar cell protects itself from overstimulation through the cholecystokinin receptor with special emphasis on the role of receptor phosphorylation. Digestion Digestion 1997;58(suppl 2):75-80 Peter H.G.M. Willems RolfL.L. Smeets Remko R. Bosch...

...Kyoko Miyasaka; Masao Masuda; Akihiro Funakoshi An Otsuka Long-Evans Tokushima Fatty (OLETF) rat does not possess cholecystokinin (CKK)-A receptor gene expression because of a genetic abnormality. We examined the CCK release and its transcription in OLETF rats in comparison with control (Long-Evans...

... translocation from the gut. The aim of the present study was to evaluate the influence of exogenous cholecystokinin (CCK) on intestinal transit time, enteric bacterial overgrowth and translocation in experimental acute liver failure induced by 90% hepatectomy. A delayed intestinal transit time was noted...

...G. Adler Pancreas Postprandial pancreatic secretion Cholecystokinin Neurohormonal interactions Secretin Digestion G Adler Department of Internal Medicine I, University of Ulm, Germany Pancreas Digestion I997:58(suppl 1):39-4I Regulation of Human Pancreatic Secretion Key Words Pancreas...

..., instructions or products referred to in the content or advertisements. 1997 Pancreatitis, acute Proenzymes Zymogens Caerulein Cholecystokinin Digestion Digestion I997;58(suppl 1):46 49 Michael L. Steer Department of Surgery. Beth Israel Hospital. Harvard Medical School. Boston. Mass.. USA...

..., instructions or products referred to in the content or advertisements. 1997 Peptide receptors Agonist Antagonist Octreotide Endothelin Cholecystokinin Bradykinin Gastrin-releasing peptide Digestion Robert T. Jensen National Institutes of I lealth. National Institutes of Diabetes. Digestive...

...] postulated in 1928 the existence of "cholecystokinin" as a "hormone mechanism for gallbladder contraction and emptying". 15 years later, Harper and Raper [3] described "pancreo­ zymin. a stimulant of pancreatic enzymes in the extracts of the small intestine'. All these activities, however, could...

... healthy non-diabetic obese subjects and 20 age-and sex-matched lean controls, fasting gallbladder volumes, gallbladder contraction in response to cephalic vagal cholinergic stimulation by modified sham feeding (MSF) and to hormonal stimulation with cholecystokinin (CCK) were studied. Gallbladder volumes...

...Hans-Karl Heim; Markus Piller; Xiahong An; Petra Kilian; Susanne Netz; Karl-Friedrich Sewing Cell isolation may impair secretory chief cell functions. To evaluate whether a monolayer culture results in a recovery, we compared the effects of cholecystokinin (CCK) octapeptide (CCK-8) on pepsinogen...

...Claus Riber; Liselotte Hojgaard; Jan Lysgaard Madsen; Jens Frederik Rehfeld; Ole Olsen The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration offish oil and trioleate. After...

...S. Evrard; A. Hoeltzel; M. Aprahamian; C. Bernard; D. Mutter; J. Marescaux; C. Damgé Biliopancreatic bypass (BPB), a bariatric surgical procedure, leads to a malnutrition-induced general visceral atrophy except for the pancreas. This work investigates the implication of cholecystokinin (CCK...

...-methylpiperidine methobromide (4-DAMP, a specific M 3 muscarinic receptor antagonist), atropine (a nonspecific muscarinic receptor antagonist), and loxiglumide (cholecystokinin, CCK, receptor antagonist) in dogs. In conscious dogs with chronic gastric and duodenal fistulas, release of PP and exocrine pancreatic...

... ). There is no increase of the GRP concentrations in peripheral blood which is also the case under physiological postprandial conditions. There is also no increase in the peripheral cholecystokinin (CCK) concentrations, in contrast to previous reports. Nevertheless other CCK-related mechanisms may play an important role...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 1993 Aminoguanidine Camostate Cholecystokinin Diamine oxidase α-Difluoromethylornithine MDL-72527 Ornithine decarboxylase Pancreatic adaptation Polyamines Putrescine...

... (postprandial vs. interdigestive secretion, protein vs. bicarbonate secretion): Somatostatin may act via inhibition of the release of circulating hormones such as cholecystokinin (CCK) and secretin or via intra-pancreatic inhibition of the release or action of CCK. Somatostatin may inhibit acetylcholine release...

... intravenous infusion of cholecystokinin (CCK8; 12.5 pmol/kg·h) or yolk intake in tests without (saline) and with intravenous infusion of N G -monomethyl- L -arginine ( L -NMMA; 4.0 μmol/kg·h) and/or L -arginine (1 mmol/kg·h). The plasma CCK level was determined by radioimmunoassay. It was found that the basal...

...Andrzej Dabrowski; Katharina M. Detjen; Craig D. Logsdon; John A. Williams It was recently found that cholecystokinin (CCK) activates mitogen-activated protein kinases (MAPK) in isolated rat pancreatic acini. The present study evaluates whether one or both types of CCK receptors are capable of MAPK...

... contraction is probably mediated by M 1 muscarinic receptors while the duodenal phase of gallbladder contraction is partially mediated by M 1 receptors. Pirenzepine Gallbladder contraction Sham feeding Meal-stimulated contraction Muscarinic receptors Cholecystokinin Original Paper Digestion 1992;51...

.... 1992 Cholecystokinin Fundus Hamster Hyperplasia Pancreaticobiliary diversion Proliferation Stomach Original Paper Digestion 1992;51:133-139 M ing Chu* Jens F. Rehfeldb Kurt Borcha a Department of Surgery, University Hospital of Linköping, Sweden, and b Department of Clinical Chemistry...