...W.F. Caspary; H. Lücke Since biguanides are known to inhibit hexose and amino acid absorption in vivo and in vitro as well as vitamin B 12 absorption the effect of phenethylbiguanide on taurocholate (TC) and water absorption was measured in rat ileum in vivo. Phenethylbiguanide exhibited a time...

...M. Eisner; W. Berger In contrast to its effect in animal experiments, biguanide is shown to have no effect on gastric emptying in man. Gastric emptying was assessed by the double sampling test meal 2 h after placebo or 1 g of dimethylbiguanide (Metformin). The test meal consisted of 750 ml of water...