Inhibitory Effects of Probiotic and Gastro-Intestinal Bacteria on Helicobacter pylori in vitro

2.

WHO

.

Antibiotic resistance: multi-country public awareness survey I

.

2017

. [Online]. Available from: https://www.who.int/news/item/27-02-2017-who-publishes-list-of-bacteria-for-which-new-antibiotics-are-urgently-needed

3.

Malfertheiner

P

,

Megraud

F

,

Rokkas

T

,

Gisbert

JP

,

Liou

JM

,

Schulz

C

, et al.

Management of Helicobacter pylori infection: the Maastricht VI/Florence consensus report

.

Gut

.

2022

;

71

(

9

):

1724

–

62

.

4.

Mégraud

F

,

Bruyndonckx

R

,

Coenen

S

,

Wittkop

L

,

Huang

TD

,

Hoebeke

M

, et al.

Helicobacter pylori resistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the community

.

Gut

.

2021

;

70

(

10

):

1815

–

22

.

5.

McFarland

LV

,

Huang

Y

,

Wang

L

,

Malfertheiner

P

.

Systematic review and meta-analysis: multi-strain probiotics as adjunct therapy for Helicobacter pylori eradication and prevention of adverse events

.

United Eur Gastroenterol J

.

2016

;

4

(

4

):

546

–

61

.

6.

de Klerk

N

,

Maudsdotter

L

,

Gebreegziabher

H

,

Saroj

SD

,

Eriksson

B

,

Eriksson

OS

, et al.

Lactobacilli reduce Helicobacter pylori attachment to host gastric epithelial cells by inhibiting adhesion gene expression

.

Infect Immun

.

2016

;

84

(

5

):

1526

–

35

.

7.

Berry

V

,

Jennings

K

,

Woodnutt

G

.

Bactericidal and morphological effects of amoxicillin on Helicobacter pylori

.

Antimicrob Agents Chemother

.

1995

;

39

(

8

):

1859

–

61

.

8.

Bode

G

,

Mauch

F

,

Malfertheiner

P

,

The coccoid forms of Helicobacter pylori. Criteria for their viability

.

Epidemiol Infect

.

1993

;

111

(

3

):

483

–

90

.

9.

Janas

B

,

Czkwianianc

E

,

Bak-Romaniszyn

L

,

Bartel

H

,

Tosik

D

,

Płaneta-Małecka

I

.

Electron microscopic study of association between coccoid forms of Helicobacter pylori and gastric epithelial cells

.

Am J Gastroenterol

.

1995

;

90

(

10

):

1829

–

33

.

10.

Krzyżek

P

,

Biernat

MM

,

Gościniak

G

.

Intensive formation of coccoid forms as a feature strongly associated with highly pathogenic Helicobacter pylori strains

.

Folia Microbiol

.

2019

;

64

(

3

):

273

–

81

.

11.

Khosravi

Y

,

Dieye

Y

,

Loke

MF

,

Goh

KL

,

Vadivelu

J

.

Streptococcus mitis induces conversion of Helicobacter pylori to coccoid cells during Co-culture in vitro

.

PLoS One

.

2014

;

9

(

11

):

e112214

–

11

.

12.

She

F-F

,

Lin

J-Y

,

Liu

J-Y

,

Huang

C

,

Su

D-H

.

Virulence of water-induced coccoid Helicobacter pylori and its experimental infection in mice

.

World J Gastroenterol

.

2003

;

9

(

3

):

516

–

20

.

13.

Liang

Y

,

Yan

J

,

Chen

Z

,

Gu

Q

,

Li

P

.

Antibacterial effects of bacteriocin PLNC8 against Helicobacter pylori and its potential mechanism of action

.

Foods

.

2022

;

11

(

9

):

1235

.

14.

Pinchuk

IV

,

Bressollier

P

,

Verneuil

B

,

Fenet

B

,

Sorokulova

IB

,

Mégraud

F

, et al.

In vitro anti- Helicobacter pylori activity of the probiotic strain Bacillus subtilis 3 is due to secretion of antibiotics

.

Antimicrob Agents Chemother

.

2001

;

45

(

11

):

3156

–

61

.

15.

Mukai

T

,

Asasaka

T

,

Sato

E

,

Mori

K

,

Matsumoto

M

,

Ohori

H

.

Inhibition of binding of Helicobacter pylori to the glycolipid receptors by probiotic Lactobacillus reuteri

.

FEMS Immunol Med Microbiol

.

2002

;

32

(

2

):

105

–

10

.

16.

Chen

Y-H

,

Tsai

WH

,

Wu

HY

,

Chen

CY

,

Yeh

WL

,

Chen

YH

, et al.

Probiotic lactobacillus spp. act against Helicobacter pylori-induced inflammation

.

J Clin Med

.

2019

;

8

(

1

):

90

.

17.

El-Adawi

H

,

El-Sheekh

M

,

Khalil

M

,

El-Deeb

N

,

Hussein

M

.

Lactic acid bacterial extracts as anti-Helicobacter pylori: a molecular approach

.

Ir J Med Sci

.

2013

;

182

(

3

):

439

–

52

.

18.

Rezaee

P

,

Kermanshahi

RK

,

Falsafi

T

.

Antibacterial activity of lactobacilli probiotics on clinical strains of Helicobacter pylori

.

Iran J Basic Med Sci

.

2019

;

22

(

10

):

1118

–

24

.

19.

Coconnier

MH

.

Antagonistic activity against Helicobacter infection in vitro and in vivo by the human Lactobacillus acidophilus strain LB

.

American Society for Microbiology

;

1998

.

Vol. 64

; p.

4573

–

80

.

20.

Lorca

GL

,

Wadström

T

,

Valdez

GFD

,

Ljungh

Å

.

Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro

.

Curr Microbiol

.

2001

;

42

(

1

):

39

–

44

.

21.

Page

MJ

,

McKenzie

JE

,

Bossuyt

PM

,

Boutron

I

,

Hoffmann

TC

,

Mulrow

CD

, et al.

The PRISMA 2020 statement: an updated guideline for reporting systematic reviews

.

BMJ

.

2021

;

372

:

n71

.

22.

Higgins

JP

,

Altman

DG

,

Gøtzsche

PC

,

Jüni

P

,

Moher

D

,

Oxman

AD

, et al.

The Cochrane Collaboration's tool for assessing risk of bias in randomised trials

.

BMJ

.

2011

;

343

:

d5928

. (in eng).

23.

Higgins

JP

,

Altman

DG

.

Assessing risk of bias in included studies

.

Cochrane Handbook Syst Rev Interventions

.

2008

:

187

–

241

.

24.

Bik

EM

,

Eckburg

PB

,

Gill

SR

,

Nelson

KE

,

Purdom

EA

,

Francois

F

, et al.

Molecular analysis of the bacterial microbiota in the human stomach

.

Proc Natl Acad Sci U S A

.

2006

;

103

(

3

):

732

–

7

.

25.

Sheh

A

,

Fox

JG

.

Helicobacter pylori pathogenesis the role of the gastrointestinal microbiome in Helicobacter pylori pathogenesis

.

2013

;

0976

.

26.

Schulz

C

,

Schütte

K

,

Koch

N

,

Vilchez-Vargas

R

,

Wos-Oxley

ML

,

Oxley

APA

, et al.

The active bacterial assemblages of the upper GI tract in individuals with and without Helicobacter infection

.

Gut

.

2018

;

67

(

2

):

216

–

25

.

27.

Probiotics in food Health and nutritional properties and guidelines for evaluation

.

2006

. [Online]. Available from: https://www.fao.org/3/a0512e/a0512e.pdf

28.

Gill

HS

,

Guarner

F

.

Probiotics and human health: a clinical perspective

.

Postgrad Med J

.

2004

;

80

(

947

):

516

–

26

.

29.

Fernandez

MF

,

Boris

S

,

Barbes

C

.

Probiotic properties of human lactobacilli strains to be used in the gastrointestinal tract

.

J Appl Microbiol

.

2003

;

94

(

3

):

449

–

55

.

30.

Gotteland

M

,

Andrews

M

,

Toledo

M

,

Muñoz

L

,

Caceres

P

,

Anziani

A

, et al.

Modulation of Helicobacter pylori colonization with cranberry juice and Lactobacillus johnsonii La1 in children

.

Nutr

.

2008

;

24

(

5

):

421

–

6

.

31.

Lim

S-M

.

Anti-Helicobacter pylori activity of antimicrobial substances produced by lactic acid bacteria isolated from Baikkimchi

.

J Korean Soc Appl Biol Chem

.

2014

;

57

(

5

):

621

–

30

.

32.

De Vuyst

L

,

Vincent

P

,

Makras

E

,

Leroy

F

,

Pot

B

.

Peptide extracts from cultures of certain lactobacilli inhibit Helicobacter pylori

.

Probiotics Antimicrob Proteins

.

2010

;

2

(

1

):

26

–

36

.

33.

Lim

E-S

.

Purification and characterization of two bacteriocins from Lactobacillus brevis BK11 and Enterococcus faecalis BK61 showing anti-Helicobacter pylori activity

.

J Korean Soc Appl Biol Chem

.

2015

;

58

(

5

):

703

–

14

.

34.

Sgouras

D

,

Maragkoudakis

P

,

Petraki

K

,

Martinez-Gonzalez

B

,

Eriotou

E

,

Michopoulos

S

, et al.

In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus casei strain shirota

.

Appl Environ Microbiol

.

2004

;

70

(

1

):

518

–

26

.

35.

Cats

A

,

Kuipers

EJ

,

Bosschaert

MAR

,

Pot

RGJ

,

Vandenbroucke-Grauls

CMJE

,

Kusters

JG

.

Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects

.

Aliment Pharmacol Ther

.

2003

;

17

(

3

):

429

–

35

.

36.

Le Moal

VL

,

Fayol-Messaoudi

D

,

Servin

AL

.

Compound(s) secreted by Lactobacillus casei strain Shirota YIT9029 irreversibly and reversibly impair the swimming motility of Helicobacter pylori and Salmonella enterica serovar Typhimurium, respectively

.

Microbiol

.

2013

;

159

(

Pt 9

):

1956

–

71

.

37.

Aiba

Y

,

Suzuki

N

,

Kabir

AMA

,

Takagi

A

,

Koga

Y

,

Koga

Y

.

Lactic acid-mediated suppression of Helicobacter pylori by the oral administration of lactobacillus salivarius as a probiotic in a gnotobiotic murine model

.

Am J Gastroenterol

.

1998

;

93

(

11

):

2097

–

101

.

38.

Fakharian

F

,

Sadeghi

A

,

Pouresmaeili

F

,

Soleimani

N

,

Yadegar

A

.

Immunomodulatory effects of live and pasteurized Lactobacillus crispatus strain RIGLD-1 on Helicobacter pylori-triggered inflammation in gastric epithelial cells in vitro

.

Mol Biol Rep

.

2023

;

50

(

8

):

6795

–

805

.

39.

García

A

,

Navarro

K

,

Sanhueza

E

,

Pineda

S

,

Pastene

E

,

Quezada

M

, et al.

Characterization of Lactobacillus fermentum UCO-979C, a probiotic strain with a potent anti-Helicobacter pylori activity

.

Electron J Biotechnol

.

2017

;

25

:

75

–

83

.

40.

Chen

X

,

Liu

X

,

Tian

F

,

Zhang

Q

,

Zhang

H

,

Zhang

H

, et al.

Antagonistic activities of lactobacilli against Helicobacter pylori growth and infection in human gastric epithelial cells

.

J Food Sci

.

2012

;

77

(

1

):

M9

–

14

.

41.

Ushiyama

A

,

Tanaka

K

,

Aiba

Y

,

Shiba

T

,

Takagi

A

,

Mine

T

, et al.

Lactobacillus gasseri OLL2716 as a probiotic in clarithromycin-resistant Helicobacter pylori infection

.

J Gastroenterol Hepatol

.

2003

;

18

(

8

):

986

–

91

.

42.

Thuy

TTD

,

Kuo

P-Y

,

Lin

S-M

,

Kao

C-Y

.

Anti-Helicobacter pylori activity of potential probiotic Lactiplantibacillus pentosus SLC13

.

BMC Microbiol

.

2022

;

22

(

1

):

277

.

43.

Xu

B

,

Kong

J

,

Lin

Y

,

Tang

Z

,

Liu

J

,

Chen

Z

, et al.

Anti- Helicobacter pylori activity and gastroprotective effects of human stomach-derived Lactobacillus paragasseri strain LPG-9

.

Food Funct

.

2023

;

14

(

24

):

10882

–

95

.

44.

Aiba

Y

,

Nakano

Y

,

Koga

Y

,

Takahashi

K

,

Komatsu

Y

.

A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice

.

MicrobiologyOpen

.

2015

;

4

(

3

):

465

–

74

.

45.

Kim

T-S

,

Hur

JW

,

Yu

MA

,

Cheigh

CI

,

Kim

KN

,

Hwang

JK

, et al.

Antagonism of Helicobacter pylori by bacteriocins of lactic acid bacteria

.

J Food Prot

.

2003

;

66

(

1

):

3

–

12

.

46.

Hong

S-S

,

Lee

HA

,

Kim

JY

,

Jeong

JW

,

Shim

JJ

,

Lee

JL

, et al.

In vitro and in vivo inhibition of Helicobacter pylori by Lactobacilllus paracasei HP7

.

Lab Anim Res

.

2018

;

34

(

4

):

216

–

22

.

47.

Zhou

Q

,

Qureshi

N

,

Xue

B

,

Xie

Z

,

Li

P

,

Gu

Q

.

Preventive and therapeutic effect of Lactobacillus paracasei ZFM54 on Helicobacter pylori-induced gastritis by ameliorating inflammation and restoring gastric microbiota in mice model

.

Front Nutr

.

2022

;

9

:

972569

.

48.

Takeda

S

,

Igoshi

K

,

Tsend-Ayush

C

,

Oyunsuren

T

,

Sakata

R

,

Koga

Y

, et al.

Lactobacillus paracasei strain 06TCa19 suppresses inflammatory chemokine induced by Helicobacter pylori in human gastric epithelial cells

.

Hum Cell

.

2017

;

30

(

4

):

258

–

66

.

49.

Zheng

P-X

,

Fang

H-Y

,

Yang

H-B

,

Tien

N-Y

,

Wang

M-C

,

Wu

J-J

.

Lactobacillus pentosus strain LPS16 produces lactic acid, inhibiting multidrug-resistant Helicobacter pylori

.

J Microbiol Immunol Infect

.

2016

;

49

(

2

):

168

–

74

.

50.

Rokka

S

,

Pihlanto

A

,

Korhonen

H

,

Joutsjoki

V

.

In vitro growth inhibition of Helicobacter pylori by lactobacilli belonging to the Lactobacillus plantarum group

.

Lett Appl Microbiol

.

2006

;

43

(

5

):

508

–

13

.

51.

Wu

S

,

Xu

Y

,

Chen

Z

,

Chen

Y

,

Wei

F

,

Xia

C

, et al.

Lactiplantibacillus plantarum ZJ316 reduces Helicobacter pylori adhesion and inflammation by inhibiting the expression of adhesin and urease genes

.

Mol Nutr Food Res

.

2023

;

67

(

18

):

e2300241

.

52.

Zhao

K

,

Xie

Q

,

Xu

D

,

Guo

Y

,

Tao

X

,

Wei

H

, et al.

Antagonistics of Lactobacillus plantarum ZDY2013 against Helicobacter pylori SS1 and its infection in vitro in human gastric epithelial AGS cells

.

J Biosci Bioeng

.

2018

;

126

(

4

):

458

–

63

.

53.

Sunanliganon

C

,

Thong-Ngam

D

,

Tumwasorn

S

,

Klaikeaw

N

.

Lactobacillus plantarum B7 inhibits Helicobacter pylori growth and attenuates gastric inflammation

.

World J Gastroenterol

.

2012

;

18

(

20

):

2472

–

80

.

54.

Ki

M-R

,

Ghim

SY

,

Hong

IH

,

Park

JK

,

Hong

KS

,

Ji

AR

, et al.

In vitro inhibition of Helicobacter pylori growth and of adherence of cagA -positive strains to gastric epithelial cells by lactobacillus paraplantarum KNUC25 isolated from kimchi

.

J Med Food

.

2010

;

13

(

3

):

629

–

34

.

55.

Kabir

AMA

,

Aiba

Y

,

Takagi

A

,

Kamiya

S

,

Miwa

T

,

Koga

Y

.

Prevention of Helicobacter pylori infection by lactobacilli in a gnotobiotic murine model

;

1997

; p.

49

–

55

.

56.

Urrutia-Baca

VH

,

Escamilla-García

E

,

de la Garza-Ramos

MA

,

Tamez-Guerra

P

,

Gomez-Flores

R

,

Urbina-Ríos

CS

.

In vitro antimicrobial activity and downregulation of virulence gene expression on Helicobacter pylori by Reuterin

.

Probiotics Antimicrob Proteins

.

2018

;

10

(

2

):

168

–

75

.

57.

Nia

FF

,

Ghasemi

A

,

Saeidi

J

,

Mohtashami

M

.

Inhibitory activity of Limosilactobacillus reuteri isolated from camel milk against Helicobacter pylori effects in human gastric epithelial cells

.

Biotechnol Appl Biochem

.

2023

;

70

(

6

):

1941

–

53

.

58.

Okuda

K

,

Ishihara

K

,

Miura

T

,

Katakura

A

,

Noma

H

,

Ebihara

Y

.

Helicobacter pylori may have only a transient presence in the oral cavity and on the surface of oral cancer

.

Microbiol Immunol

.

2000

;

44

(

5

):

385

–

8

.

59.

Marcial

G

,

Villena

J

,

Faller

G

,

Hensel

A

,

de Valdéz

GF

.

Exopolysaccharide-producing Streptococcus thermophilus CRL1190 reduces the inflammatory response caused by Helicobacter pylori

.

Benef Microbes

.

2017

;

8

(

3

):

451

–

61

.

60.

Saracino

IM

,

Pavoni

M

,

Saccomanno

L

,

Fiorini

G

,

Pesci

V

,

Foschi

C

, et al.

Antimicrobial efficacy of five probiotic strains against Helicobacter pylori

.

Antibiotics

.

2020

;

9

(

5

):

244

.

61.

Tsai

C-C

,

Huang

L-F

,

Lin

C-C

,

Tsen

H-Y

.

Antagonistic activity against Helicobacter pylori infection in vitro by a strain of Enterococcus faecium TM39

.

Int J Food Microbiol

.

2004

;

96

(

1

):

1

–

12

.

62.

Kaur

B

,

Garg

N

,

Sachdev

A

,

Kumar

B

.

Effect of the oral intake of probiotic Pediococcus acidilactici BA28 on Helicobacter pylori causing peptic ulcer in C57bl/6 mice models

.

Appl Biochem Biotechnol

.

2014

;

172

(

2

):

973

–

83

.

63.

Nam

H

,

Ha

M

,

Bae

O

,

Lee

Y

.

Effect of Weissella confusa strain PL9001 on the adherence and growth of Helicobacter pylori

.

Appl Environ Microbiol

.

2002

;

68

(

9

):

4642

–

5

.

64.

López-Brea

M

,

Alarcón

T

,

Domingo

D

,

Díaz-Regañón

J

.

Inhibitory effect of Gram-negative and Gram-positive microorganisms against Helicobacter pylori clinical isolates

.

J Antimicrob Chemother

.

2008

;

61

(

1

):

139

–

42

.

65.

Vílchez

R

,

Lemme

A

,

Ballhausen

B

,

Thiel

V

,

Schulz

S

,

Jansen

R

, et al.

Streptococcus mutans inhibits Candida albicans hyphal formation by the fatty acid signaling molecule trans-2-decenoic acid (SDSF)

.

Chembiochem

.

2010

;

11

(

11

):

1552

–

62

.

66.

Cui

Y

,

Wang

CL

,

Liu

XW

,

Wang

XH

,

Chen

LL

,

Zhao

X

, et al.

Two stomach-originated lactobacillus strains improve Helicobacter pylori infected murine gastritis

.

World J Gastroenterol

.

2010

;

16

(

4

):

445

–

52

.

67.

Ryan

KA

,

Daly

P

,

Li

Y

,

Hooton

C

,

O’Toole

PW

.

Strain-specific inhibition of Helicobacter pylori by Lactobacillus salivarius and other lactobacilli

.

J Antimicrob Chemother

.

2008

;

61

(

4

):

831

–

4

.

68.

García

MT

,

Jones

S

,

Pelaz

C

,

Millar

RD

,

Abu Kwaik

Y

.

Acanthamoeba polyphaga resuscitates viable non-culturable Legionella pneumophila after disinfection

.

Environ Microbiol

.

2007

;

9

(

5

):

1267

–

77

.

69.

Zhou

Q

,

Xue

B

,

Gu

R

,

Li

P

,

Gu

Q

.

Lactobacillus plantarum ZJ316 attenuates Helicobacter pylori -induced gastritis in C57bl/6 mice

.

J Agric Food Chem

.

2021

;

69

(

23

):

6510

–

23

.

70.

Kõll-Klais

P

,

Mändar

R

,

Leibur

E

,

Marcotte

H

,

Hammarström

L

,

Mikelsaar

M

.

Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity

.

Oral Microbiol Immunol

.

2005

;

20

(

6

):

354

–

61

.

71.

Ahrné

S

,

Nobaek

S

,

Jeppsson

B

,

Adlerberth

I

,

Wold

AE

,

Molin

G

.

The normal Lactobacillus flora of healthy human rectal and oral mucosa

.

J Appl Microbiol

.

1998

;

85

(

1

):

88

–

94

.

72.

Farrow

JAE

,

Collins

MD

.

Notes: lactobacillus oris sp. nov. From the human oral cavity

.

Int J Syst Bacteriol

.

1988

;

38

(

1

):

116

–

8

.

73.

Anderson

AC

,

Sanunu

M

,

Schneider

C

,

Clad

A

,

Karygianni

L

,

Hellwig

E

, et al.

Rapid species-level identification of vaginal and oral lactobacilli using MALDI-TOF MS analysis and 16S rDNA sequencing

.

BMC Microbiol

.

2014

;

14

(

1

):

312

.

74.

Liljemark

WF

,

Gibbons

RJ

.

Proportional distribution and relative adherence of Streptococcus miteor (mitis) on various surfaces in the human oral cavity

.

Infect Immun

.

1972

;

6

(

5

):

852

–

9

.

75.

Denapaite

D

,

Brückner

R

,

Nuhn

M

,

Reichmann

P

,

Henrich

B

,

Maurer

P

, et al.

The genome of Streptococcus mitis B6: what is a commensal

.

PLoS One

.

2010

;

5

(

2

):

e9426

.

76.

Favaro

L

,

Campanaro

S

,

Fugaban

JII

,

Treu

L

,

Jung

ES

,

d’Ovidio

L

, et al.

Genomic, metabolomic, and functional characterisation of beneficial properties of Pediococcus pentosaceus ST58, isolated from human oral cavity

.

Benef Microbes

.

2023

;

14

(

1

):

57

–

72

.

77.

Komiyama

EY

,

Lepesqueur

LSS

,

Yassuda

CG

,

Samaranayake

LP

,

Parahitiyawa

NB

,

Balducci

I

, et al.

Enterococcus species in the oral cavity: prevalence, virulence factors and antimicrobial susceptibility

.

PLoS One

.

2016

;

11

(

9

):

e0163001

.

78.

Malfertheiner

P

,

Megraud

F

,

O’Morain

CA

,

Gisbert

JP

,

Kuipers

EJ

,

Axon

AT

, et al.

Management of Helicobacter pylori infection-the maastricht V/florence consensus report

.

Gut

.

2017

;

66

(

1

):

6

–

30

.

79.

Hsieh

PS

,

Tsai

YC

,

Chen

YC

,

Teh

SF

,

Ou

CM

,

King

VAE

.

Eradication of H elicobacter pylori Infection by the Probiotic Strains L actobacillus johnsonii MH -68 and L. salivarius ssp. salicinius AP -32

.

Helicobacter

.

2012

;

17

(

6

):

466

–

77

.

80.

Pan

M

,

Wan

C

,

Xie

Q

,

Huang

R

,

Tao

X

,

Shah

NP

, et al.

Changes in gastric microbiota induced by Helicobacter pylori infection and preventive effects of Lactobacillus plantarum ZDY 2013 against such infection

.

J Dairy Sci

.

2016

;

99

(

2

):

970

–

81

.

81.

Isobe

HI

,

Nishiyama

A

,

Takano

T

,

Higuchi

W

,

Nakagawa

S

,

Taneike

I

, et al.

Reduction of overall Helicobacter pylori colonization levels in the stomach of Mongolian gerbil by Lactobacillus johnsonii La1 (LC1) and its in vitro activities against H. pylori motility and adherence

.

Biosci Biotechnol Biochem

.

2012

;

76

(

4

):

850

–

2

.

82.

Merino

JS

,

García

A

,

Pastene

E

,

Salas

A

,

Saez

K

,

González

CL

.

Lactobacillus fermentum UCO-979C strongly inhibited Helicobacter pylori SS1 in Meriones unguiculatus

.

Benef Microbes

.

2018

;

9

(

4

):

625

–

7

.

83.

Wang

K-Y

,

Li

SN

,

Liu

CS

,

Perng

DS

,

Su

YC

,

Wu

DC

, et al.

Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt in subjects with colonized Helicobacter pylori

.

Am J Clin Nutr

.

2004

;

80

(

3

):

737

–

41

.

84.

Rosania

R

,

Minenna

MF

,

Giorgio

F

,

Facciorusso

A

,

De Francesco

V

,

Hassan

C

, et al.

Probiotic multistrain treatment may eradicate Helicobacter pylori from the stomach of dyspeptics: a placebo-controlled pilot study

.

Inflamm Allergy Drug Targets

.

2012

;

11

(

3

):

244

–

9

.

85.

Wang

S

,

Zhang

M

,

Yu

L

,

Tian

F

,

Lu

W

,

Wang

G

, et al.

Evaluation of the potential protective effects of lactobacillus strains against Helicobacter pylori infection: a randomized, double-blinded, placebo-controlled trial

.

Can J Infect Dis Med Microbiol

.

2022

;

2022

:

6432750

–

13

.

86.

Takagi

A

,

Yanagi

H

,

Ozawa

H

,

Uemura

N

,

Nakajima

S

,

Inoue

K

, et al.

Effects of lactobacillus gasseri OLL2716 on Helicobacter pylori -associated dyspepsia: a multicenter randomized double-blind controlled trial

.

Gastroenterol Res Pract

.

2016

;

2016

:

7490452

–

6

.

87.

Francavilla

R

,

Lionetti

E

,

Castellaneta

SP

,

Magistà

AM

,

Maurogiovanni

G

,

Bucci

N

, et al.

Inhibition of Helicobacter pylori infection in humans by Lactobacillus reuteri ATCC 55730 and effect on eradication therapy: a pilot study

.

Helicobacter

.

2008

;

13

(

2

):

127

–

34

.