24-hour basal gastric acid collections were obtained from 10 healthy, young (ages 22–27) male volunteers. The hourly secretory pattern, which described a circadian periodicity (low morning, high evening acid rates), was compared to mean plasma gastrin levels obtained at 4-hour intervals. No rhythm in plasma gastrin was detected over the 24-hour collection period. Hence, the circadian rhythm of basal acid secretion in man does not appear to be related to fluctuations in plasma gastrin levels.

This content is only available via PDF.
You do not currently have access to this content.