Islets of fully developed gastric mucosa i.e. containing parietal cells and sometimes pepsinogen cells were found in the duodenal cuff in 52 outof 158 gastric resection specimens. The gastric mucosa was seen significantly more often in the duodenum when the gastric resection was performed for duodenal ulceration. It is thought that the high acidity associatedwith the duodenal ulceration might be the cause forthe development of the heterotopic gastric mucosa.

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