We studied the frequency and composition of circulating immune complexe (CIC) in patients with chronic persistent non-A, non-B (NANB) hepatitis and in convalescen persons after an apparently normal recovery from acute NANB hepatitis. 10 of 16 patient with chronic NANB hepatitis and 5 of 11 convalescent persons after acute NANB hepatiti had CIC as detected by the Raji cell technique. CIC in chronic NANB hepatitis were com posed of IgG, C3, and in 7 of 10 cases also IgM, while in CIC from convalescent persons Ig( and C3 were present, too, but IgM was detected in only 1 case. Viral antigens within the CI( were not detectable in any case while 14 of 16 chronic NANB hepatitis patients were found t < have free virus-associated antigen in serum.

This content is only available via PDF.
You do not currently have access to this content.