This study evaluated the effect of a cellulose meal and a cellulose-oleic acid meal on gastroduodenal motility and gastric emptying. The cellulose meal produced a high antral motility index (100 ± 34 V/10 min) and a high proportion (80.2%) of propulsive duodenal contractions. The oleic acid meal was associated with a significantly lower antral motility index (70 ± 34 V/10 min), a high proportion (78.7%) of segmental duodenal contractions, and a reduced emptying rate (half time 93 ± 18 versus 30 ± 7 min). Results indicate that the inert cellulose meal is advantageous in studying the effects of different nutrients on gastrointestinal motility.

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