In 12 normals serum calcitonin (CT) concentration decreased significantly when eating with a return to basal value and a significant postprandial fall. No difference was observed in the food-stimulated CT secretion between duodenal ulcer patients and normals. In 25 patients with ulcer negative dyspepsia a significant increase in serum CT concentration occurred during food intake followed by a return to basal level and a secondary significant rise. The pattern in patients with ulcer negative dyspepsia differed significantly from patients with duodenal ulcer and normals.

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