It cannot be denied that the fibre theory is attractive and appears to be firmly based in ‘common sense’ – one would expect a priori that all of the statements are likely to be true. When further investigated, however, we find that ‘common sense’ has again let us down and that an expected relation is in fact reversed simply because the situation is much more complex than expected (the best example is the lack of relation between bowel transit time and the degree of bacterial degradation of fecal steroids, etc.). There is little virtue in criticising a hypothesis unless a better one can be suggested as a replacement. I would therefore like to reiterate the hypothesis that I and my colleagues have been investigating. We believe that it offers a better rationalisation of the facts.

Journal Section:
Progress Report
Keywords:
Bacterial infections, β-Glucuronidase, Bile salts, Bran, Carcinogens, Colon, Dietary fat, Dietary fibre, Epidemiology, Gastrointestinal motility
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© 1974 S. Karger AG, Basel
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1974
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