.... Interestingly, the between-network connectivity of the FPCN and the DMN was negatively correlated with deep white matter hyperintensities (DWMH) volume in CSVD subjects. Conclusion: These findings suggest that cognitive alterations of CSVD subjects may be mainly regulated by the FPCN that correlates with DWMH...

... completed the Mini-Mental State Examination, Taiwanese FAB (TFAB), Category Fluency, and Chinese Version of the Verbal Learning Test, and underwent magnetic resonance imaging. White matter hyperintensities were rated according to the Scheltens scale. Results: TFAB total scale and its Orthographical Fluency...

.... Normal ageing Magnetic resonance imaging Hippocampal volume White matter hyperintensities White matter changes Vascular risk factors In our constantly ageing society with an associated increase in neurodegenerative diseases, one major aim of research is to identify people at risk...

... remains incompletely understood. With the development of brain MRI, it is now possible to detect small-vessel disease, whose prevalence and severity increase with age. The first types of small-vessel disease to be described were white matter hyperintensities (WMHs). More recently, small areas of signal...

... using SPSS software version 14.0 (SPSS, Inc., Chicago, Ill., USA). Table 3 General cognitive profiles of the patients with minimal, moderate, and severe WMH White matter hyperintensities Neuropsychology of dementia Alzheimerߣs disease Subcortical vascular dementia Many...

... assessments, were available from 55 patients. Changes in cognitive performance over time were expressed as a regression-based index (RBI). Automated volumetric measurements of total brain, lateral ventricles and white matter hyperintensities were performed. The relationship between baseline microvascular...

... of neuropsychiatric symptoms in stroke patients with age-related confluent white matter hyperintensities (WMH). Methods: The Neuropsychiatric Inventory was utilized to detect the presence of 12 symptoms. Multivariate logistic regression models were used to identify clinical and neuroimaging correlates of the presence...

...S.S. Staekenborg; H. de Waal; F. Admiraal-Behloul; F. Barkhof; J.H.C. Reiber; P. Scheltens; Y.A.L. Pijnenburg; H. Vrenken; W.M. van der Flier Purpose: To determine the frequency of neurological signs in a memory clinic population and to explore their associations with white matter hyperintensity...

... imaging White matter hyperintensities White matter lesions Original Research Article Dement Geriatr Cogn Disord 2008;26:424 431 DOI: 10.1159/000165355 Accepted: August 5, 2008 Published online: October 23, 2008 White Matter Lesion Subtypes and Cognitive Deficits in Patients with Memory Impairment...

.... Cognitive impairment Neuroimaging Heart failure White matter hyperintensities Original Research Article Dement Geriatr Cogn Disord 2007;24:418 423 DOI: 10.1159/000109811 Accepted: August 3, 2007 Published online: October 15, 2007 Neuroimaging and Correlates of Cognitive Function among Patients...

...Roberta Rossi; Cristina Geroldi; Lorena Bresciani; Cristina Testa; Giuliano Binetti; Orazio Zanetti; Giovanni B. Frisoni Aim: To describe the clinical and neuropsychological features of mild cognitive impairment (MCI) patients with medial temporal atrophy (MTA), white matter hyperintensities (WMH...

... on the cholinergic pathways. Results: Over the 24-month period, the results of the CDT showed more apparent and constant association with white matter hyperintensities (WMH) and lesions on the cholinergic pathways than the HDS-R. WMH may enhance, while lesions on the cholinergic pathways may attenuate sensitivity...

... measures, hippocampal volumes, volumes of amygdala and white matter hyperintensities after adjusting for age, gender, years of education, depression and physical disability. None of the neuroanatomical substrates appeared as predictors of MCI. The only predictors were higher depression scores and fewer...

...Wiesje M. van der Flier; Huub A.M. Middelkoop; Annelies W.E. Weverling-Rijnsburger; Faiza Admiraal-Behloul; Eduard L.E.M. Bollen; Rudi G.J. Westendorp; Mark A. van Buchem Objective: To investigate the independent associations between medial temporal lobe atrophy and white matter hyperintensities...