... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Oxidative stress Isoprostanes Plasma Superoxide dismutase Presenilin-1 Amyloid β...

... UCLA Medical Center, Sylmar, Calif., and gVirginia Commonwealth University Medical School, Richmond, Va., USA; hDepartment of Neuropsychology, National Institute of Neurology and Neurosurgery, Mexico City, Mexico Key Words Familial Alzheimer s disease Headache Migraine Presenilin-1 Amyloid...

... and presenilin-1 (PS-1) and/or synaptic proteins, the levels of PS-1 and rab3a, a specific synaptic vesicle protein, were also determined in the same tissue samples. The level of APP was almost the same in the association cortical regions, primary cortex, and limbic structures and in the subcortical structures...

...Kazuyuki Ikeda; Katsuya Urakami; Kenji Isoe; Kousaku Ohno; Kenji Nakashima The presenilin-1 (PS-1) gene was recently identified as one of the causative genes in the early onset of familial Alzheimer’s disease (AD). Analysis of the PS-1 gene is thought to be useful in clarifying the pathogenesis...