... normal (CN) individuals. Domain-averaged Z-scores were adjusted for age, sex, and education followed by Wald cluster analysis of residuals. Magnetic resonance imaging and positron emission tomography comparisons of EOAD clusters to age-matched CN were done using Statistic Parametric Mapping 8. Cluster...

...Yejin Kim; Paul Rosenberg; Esther Oh Background: Molecular imaging of brain amyloid for the diagnosis of Alzheimer’s disease (AD) using positron emission tomography (PET) has been approved for use in clinical practice by the Food and Drug Administration (FDA) since 2012. However, the clinical...

...Carl Fredrik Eliassen; Ivar Reinvang; Per Selnes; Tormod Fladby; Erik Hessen Background/Aims: To investigate the correspondence between neuropsychological single measures and variation in fludeoxyglucose positron emission tomography (FDG PET) glucose metabolism and magnetic resonance imaging (MRI...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Positron emission tomography Appropriate use criteria Alzheimer’s disease Amyloid imaging Florbetapir Despite...

..., and APP) have been identified in patients with early-onset AD. Methods: We performed gene sequencing in PSEN1, PSEN2, and APP in 61 AD and 35 FTD Chinese patients. Amyloid load using 11 C-labeled Pittsburgh compound B ( 11 C-PIB) positron emission tomography (PET) and cerebral glucose metabolism using 18...

... to identify biomarkers for specific clinical manifestations of PD symptoms, including both motor and, importantly, nonmotor symptoms. 20 11 2012 22 2 2013 Parkinson’s disease Positron emission tomography Glucose metabolism Cognition Emotion Nonmotor features of Parkinson’s disease...

... photon emission computed tomography/positron emission tomography) of each variant and studied serum progranulin levels, APOE genotype and Alzheimer’s disease (AD)-cerebrospinal fluid (CSF) biomarkers. Cases with a first-degree family history of early-onset dementia were genetically tested. Results: Ten...

.... Frontotemporal lobar degeneration-clinical dementia rating Semantic dementia Clinical dementia rating Positron emission tomography Clinical dementia staging Original Research Article Dement Geriatr Cogn Disord 2012;34:300 306 DOI: 10.1159/000345506 Accepted: October 29, 2012 Published online: November 30...

..., magnetic resonance imaging (MRI) scans, fluorodeoxyglucose-positron emission tomography (PET) scans, and Pittsburgh compound B (PiB)-PET images of these patients. Results: In the early stages, these patients developed memory disturbances in a similar rate to patients with sporadic AD. Despite their memory...

... assessments and dynamic PiB positron emission tomography imaging. Results: A linear multiple regression model showed that greater IADL impairment was associated with greater global PiB retention in all subjects (R 2 = 0.40; unstandardized partial regression coefficient, β = 5.8; p = 0.0002) and in MCI...

...He Shao; Nobuyuki Okamura; Kentaro Sugi; Shozo Furumoto; Katsutoshi Furukawa; Manabu Tashiro; Ren Iwata; Hiroshi Matsuda; Yukitsuka Kudo; Hiroyuki Arai; Hiroshi Fukuda; Kazuhiko Yanai Aim: To determine early brain changes in the distribution of an amyloid positron emission tomography (PET) probe...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer’s disease Positron emission tomography Magnetic resonance imaging Atrophy-hypometabolism mismatch Voxel-based analysis Original Research Article Dement Geriatr Cogn Disord 2010;29:37...

... suggest that functional changes may be more prominent than structural changes in MCI. 18 08 2008 6 11 2008 Positron emission tomography Voxel-based morphometry Mild cognitive impairment Hippocampus Original Research Article Dement Geriatr Cogn Disord 2008;26:490 498 DOI: 10.1159...

... to in the content or advertisements. Positron emission tomography Cerebrospinal fluid β-Amyloid Alzheimerߣs disease Mild cognitive impairment Pittsburgh compound B Original Research Article Dement Geriatr Cogn Disord 2008;26:378 383 DOI: 10.1159/000163927 Accepted: July 30, 2008 Published online...

...J. Diehl-Schmid; T. Grimmer; A. Drzezga; S. Bornschein; R. Perneczky; H. Förstl; M. Schwaiger; A. Kurz Background: Semantic dementia (SD). Objective: To identify the pattern of decline of cerebral glucose metabolism in SD using cerebral 18 F-fluoro-2-desoxy- D -glucose positron emission tomography...

..., g Department of Physiopathology, University of Florence, Florence, Italy Key Words Frontotemporal dementia Positron emission tomography Apathy Disinhibition Social conduct Abstract Orbitofrontal metabolic impairment is characteristic of the frontal variant of frontotemporal dementia (fv-FTD...

...Natascha Döbert; Johannes Pantel; Lutz Frölich; Nadja Hamscho; Christian Menzel; Frank Grünwald Objective: The diagnostic potential of F-18-2-fluoro-2-deoxy- D -glucose positron emission tomography (PET) and technetium-99m hexamethylpropylene amine oxime single-photon emission tomography (SPET...

... studied in the rhesus monkey by means of positron emission tomography. Binding to milameline cholinergic receptors was quantified using the muscarinic receptor antagonist [ 11 C]-N-methyl-4-piperidinylbenzilate ([ 11 C]NMP), and the effects on nicotine receptor binding were measured with (S) -[ 11 C...

... Informatique Médicale, University Hospital, CHRU de Lille, Faculté de Médecine, Université de Lille-II, Lille, France Key Words Single-photon emission computed tomography W Positron emission tomography W Neurodegenerative dementia Abstract The identification of new nosological forms such as Lewy body disease...

... with Alzheimer’s disease (AD). To examine these hypotheses, we studied the regional cerebral metabolic rate of glucose (rCMRglc) in patients with a clinical diagnosis of DLB or AD, using 18 F-fluorodeoxyglucose and positron emission tomography. The subjects consisted of 15 DLB patients with parkinsonism, 7 DLB...