...Alfonsina D’Iorio; Edoardo Nicolò Aiello; Carmine Vitale; Marianna Amboni; Federico Verde; Vincenzo Silani; Nicola Ticozzi; Andrea Ciammola; Barbara Poletti; Gabriella Santangelo Introduction: This study aimed to assess the diagnostics and ecological validity of the Parkinson’s Disease Cognitive...

...Shiying Bu; Wuchao Liu; Xia Sheng; Lingjing Jin; Qing Zhao Introduction: The aim of the study was to systematically analyze the therapeutic effectiveness of hyperbaric oxygen therapy compared with conventional drug therapy in patients with Parkinson’s disease. Methods: PubMed, Web of Science...

... burden. The drugs with anticholinergic effects are used in treatment of motor and nonmotor symptoms of Parkinson’s disease (PD). Therefore, it is important to screen for polypharmacy and anticholinergic burden in PD patients with mild cognitive impairment (MCI). Methods: This cross-sectional study...

...Daniela Renftle; Sara Becker; Kathrin Brockmann; Thomas Gasser; Katja Michaelis; Susanne Solbrig; Patricia Sulzer; Andreas Johnen; Inga Liepelt-Scarfone Introduction: Ideomotor apraxia, a disorder of skilled movements affecting limbs and/or face, can be seen in patients with Parkinson’s disease (PD...

...Katrine Svaerke; Andreas Kirknaes Faerk; Asta Riis; Susanne Ebba Maja Stiegnitz von Ehrenfels; Jesper Mogensen; Annemette Lokkegaard Background: Cognitive decline in Parkinson’s disease (PD) has become increasingly recognized in recent years, and there is a need to identify methods for cognitive...

...), against a no-therapy (NT) condition in patients with Parkinson’s disease and against healthy controls (HCs) with regard to the change in or enhancement of cognitive abilities. Methods: The 4 groups (rSLT: N = 16; rBMT: N = 10; NT: N = 18; and HC: N = 17) were matched for age, sex, and educational level...

...Christian Saleh; Antonia Meyer; Menorca Chaturvedi; Selina Beltrani; Ute Gschwandtner; Peter Fuhr Objective: Deep brain stimulation (DBS) in Parkinson’s disease (PD) is associated with an increased risk of post-operative cognitive deterioration. Preoperative neuropsychological testing can...

...Santiago R. Unda; Aldana M. Antoniazzi; David J. Altschul; Roberta Marongiu Introduction: Peripheral and central nervous system inflammation have been linked to the classic symptoms of Parkinson’s disease (PD) and Alzheimer’s disease (AD). However, it remains unclear whether the analysis of routine...

...Wei-Che Lin; Cheng-Hsien Lu; Pai-Yi Chiu; Shieh-Yueh Yang Background: A previously published paper (referred to as the original cohort) showed that using a cutoff value of 116.1 fg/mL for the plasma total α-synuclein concentrations could discriminate Parkinson’s disease (PD) patients from normal...

...Muhammad Tufail; Ishtiaq Hassan Introduction: Parkinson’s disease is the second most common neurodegenerative disease. The disease is more prevalent in aged individuals compared to young ones. Aim: The present study aimed to investigate the factors associated with PD in the population of Khyber...

... Short-term memory Long-term memory Serial position effects Parkinson’s disease Alzheimer’s disease Mild cognitive impairment Dementia Whereas cognitive profiles in nondemented patients with Parkinson’s disease (PD) have traditionally been seen as predominantly dysexecutive due...

.... Gerstenecker; Sandra Weintraub; William Reginold; Connie Marras Background: Clinical monitoring of patients with Parkinson’s disease (PD) for cognitive decline is an important element of care. The Montreal Cognitive Assessment (MoCA) has been proposed to be a sensitive tool for assessing cognitive impairment...

...Cristina Nombela; Andrés Lozano; Clara Villanueva; Juan A. Barcia Background/Aim: The prevalence of cognitive symptoms in recently diagnosed Parkinson’s disease (PD) patients may be as high as 60%. We report a novel deep brain stimulation (DBS) strategy targeting both motor and cognitive symptoms...

...Efrat Dagan; Ilana Schlesinger; Alina Kurolap; Mareemar Ayoub; Maria Nassar; Judith Peretz-Aharon; Ruth Gershoni-Baruch Background/Aim: Parkinson's disease (PD) is associated with mutations in LRRK2 , GBA , and SMPD1 genes. We describe the clinical characteristics of PD patients related...

... are common in Parkinson's disease (PD) patients. The aim of this study was to investigate whether variations within the normal ranges of thyroid function are related to cognitive function in early PD without dementia. Methods: Eighty-four euthyroid patients with early PD underwent evaluation of their thyroid...

...) and Parkinson's disease with dementia (PDD). This study aimed to evaluate whether the cerebrospinal fluid (CSF) amyloid-β (Aβ) 1-42 /Aβ 1-40 ratio, measured by a novel method, could improve the differential diagnosis of AD, DLB and PDD. Method: CSF levels of Aβ 1-40 and Aβ 1-42 in patients with PDD, DLB, AD...

...S. Laatu; M. Karrasch; K. Martikainen; R. Marttila Background: Neuropsychiatric symptoms and impairment in performing activities of daily living (ADL) in patients with Parkinson's disease (PD) are strong predictors of the overall caregiver burden and they increase the risk for nursing home...

...Chaorui Huang; Lisa D. Ravdin; Melissa J. Nirenberg; Panida Piboolnurak; Lawrence Severt; James S. Maniscalco; Lilja Solnes; Benjamin J. Dorfman; Claire Henchcliffe Aim: We sought to identify markers of motor and nonmotor function in Parkinson's disease (PD) using advanced neuroimaging techniques...

...Javier Pagonabarraga; Beatriz Gómez-Ansón; Ramon Rotger; Gisela Llebaria; Carmen García-Sánchez; Berta Pascual-Sedano; Alexandre Gironell; Manuel Delfino; Jaume Ruscalleda; Jaime Kulisevsky Frontal subcortical cognitive defects are predominant in Parkinson’s disease (PD). Temporal lobe dysfunction...

...Nobuto Shibata; Yumiko Motoi; Hiroyuki Tomiyama; Tohru Ohnuma; Bolati Kuerban; Katrin Tomson; Miwa Komatsu; Nobutaka Hattori; Heii Arai Background/Aims: Several candidate genes were suggested to modify the susceptibility to both Alzheimer’s disease (AD) and Parkinson’s disease (PD). Symptoms...