... physical activity interventions are commonly recommended for individuals with type 2 diabetes (T2D) and overweight or obesity. We examined the impact of randomization to an intensive lifestyle intervention (ILI) on trajectories of cognitive function over 10 years in a cohort of participants in a randomized...

...Luxia Jiang; Yingying Wang; Lingying Su; Huimin Ren; Cuiwei Wang; Jianzhong Chen; Xiaobin Fu Background/Aims: Obesity is associated with chronic inflammation and cognitive decline, and is considered a major risk factor for neurodegeneration. Meanwhile, neuroinflammation is important...

... (POCD), but little is known of risk factors predisposing patients to POCD. Our objective was to estimate the risk of POCD associated with exposure to preoperative diabetes, hypertension, and obesity. Methods: Original data from 3 randomised controlled trials (OCTOPUS, DECS, SuDoCo) were obtained...

...Andreas Ihle; Ute Mons; Laura Perna; Michel Oris; Delphine Fagot; Rainer Gabriel; Matthias Kliegel Aims: The present study set out to investigate the relation of obesity to performance in verbal abilities, processing speed, and cognitive flexibility and its interplay with key correlates...

...-density lipoprotein (HDL) and impaired fasting glucose. Metabolic syndrome Cognition Cognitive decline Obesity Hypertension Dementia National Institutes of Health (NIH) 10.13039/100000002 Emerging evidence links the metabolic syndrome (MetS) to cognitive decline...

...Adina Zeki Al Hazzouri; Mary N. Haan; Rachel A. Whitmer; Kristine Yaffe; John Neuhaus Background/Aims: Central obesity is a risk factor for cognitive decline. Leptin is secreted by adipose tissue and has been associated with better cognitive function. Aging Mexican Americans have higher levels...

... conclusive [ 1,2,3 ]. Vascular risk factors associated with dementia and cognitive impairment include hypertension, hypercholesterolemia, diabetes, obesity and smoking. It is controversial whether or not some of these factors have a direct impact on the development of the specific neuropathological lesions...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cognition Vascular risk factors Aging Hypertension Obesity Hyperglycemia Hypercholesterolemia Cardiovascular risk factors play an important role...

...% CI = 1.70–2.89), obesity (2.94; 2.44–3.03), and hypertension (2.73; 1.81–3.08), even after adjustments for several confounding factors. Elevated BMI (>25) (2.26; 1.42–2.62) and hypertension (3.14; 1.83–3.40) from midlife to late life also increased the risk of WML. In addition, an association...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adiposity Obesity Cognition Mental ability National Institutes of Health (NIH) 10.13039/100000002 Original Research Article Dement Geriatr Cogn Disord...

...Seul-Ki Jeong; Hae-Sung Nam; Myong-Ho Son; Eui-Ju Son; Ki-Hyun Cho This study aimed to investigate associations between obesity and poor cognitive performance using data from a community study of 467 individuals aged ≧65 years in South Korea. Cognitive function was ascertained using the Korean Mini...