... ]. Catechol-O-methyltransferase (COMT) is involved in the modulation of dopamine in the prefrontal cortex (PFC), where its resultant enzyme operates postsynaptically by inactivating neurotransmission [ 2,3 ]. COMT contains a functional polymorphism, which enables the substitution of valine (Val...

... for other psychiatric disorders have been implicated in BPSD; however, this is the first known investigation of the dopamine transporter (DAT1) gene in BPSD. Methods: Our large cohort of 395 patients with probable Alzheimer’s disease was dichotomised into whether they had ever suffered from a given symptom...

...), glutathione (GLU) and total antioxidant capacity in the blood of DLB, AD and control subjects. The state of nigrostriatal dopaminergic system was also assessed in vivo by using a radioactive ligand with an affinity for the dopamine pre-synaptic receptors and by imaging with single-photon emission tomography...

... the performance of a group of PD patients in visual-spatial and visual-object WM tasks and to investigate the effect of administering the dopaminergic agonist apomorphine (experiment 1) or the dopamine precursor L -dopa (experiment 2) on the performance of tests assessing these functions. To study WM processes...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Comparative studies Dopamine Dorsolateral Frontotemporal dementia Idazoxan Noradrenaline Orbitofrontal Prefrontal...