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Keywords: Crenezumab
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Journal Articles
Lessons Learnt from the Second Generation of Anti-Amyloid Monoclonal Antibodies Clinical Trials
FreeSubject Area:
Topic Article Package: Moksha
, Geriatrics and Gerontology
, Neurology and Neuroscience
, Psychiatry and Psychology
Dement Geriatr Cogn Disord (2020) 49 (4): 334–348.
Published Online: 15 December 2020
..., that have progressed to phase 3 clinical trials. Specifically, we discuss the 4 clinical trial programs of Solanezumab (targets Aβ monomers), Aducanumab (targets Aβ oligomers and plaques), Crenezumab (targets Aβ oligomers), and Gantenerumab (targets Aβ fibrils) which are all exogenous monoclonal antibodies...