... and raised perioperative cortisol, cytokine, cobalamin and homocysteine levels. Methods: The study recruited 113 consecutive adult patients scheduled for cardiac surgery with cardiopulmonary bypass. The patients were examined preoperatively with the Montreal Cognitive Assessment and Trail Making Test...

...Karin Nilsson; Lars Gustafson; Björn Hultberg Background: A moderate elevation of plasma total homocysteine (tHcy) is considered a potential risk factor for Alzheimer’s disease (AD). Methods: We have investigated the main determinants (age, renal impairment, cobalamin/folate status and the presence...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer’s disease Cobalamin Creatinine Dementia Depression Folate Homocysteine Mild cognitive impairment Psychogeriatric patients Vascular dementia Vascular disease Many studies...

... Gustafson a Björn Hultberg b a Departments of Psychogeriatrics, Clinical Science and b Laboratory Medicine, Division of Clinical Chemistry, Lund University Hospital, Lund, Sweden Key Words Cobalamin Cognition Creatinine Cystatin C Folate Homocysteine Psychogeriatric patients Vascular disease...

... determinants age and presence of vascular disease. The determination of plasma tHcy in elderly patients with mental illness may help to identify patients in need of more intensive treatment. Cobalamin Creatinine Cystatin C Folate Homocysteine Mortality Psychogeriatric patients Vascular disease ©...

... without vascular disease even after exclusion of patients with folate/cobalamin deficiency. Patients with elevated serum creatinine with or without vascular disease exhibited significantly increased plasma tHcy compared to the respective groups of patients without elevated serum creatinine. Patients...

... that elevated plasma tHcy in mental illness is mainly due to concomitant vascular disease. Methods: We have investigated plasma tHcy, cobalamin/folate status, renal function and the presence of vascular disease in patients with vascular dementia (VaD, n = 501), Alzheimer’s disease (AD, n = 300), depression (n...

... Science and Laboratory Medicine, and bDivision of Clinical Chemistry, Lund University Hospital, Lund, Sweden Key Words Cobalamin Creatinine Folate Homocysteine Memory complaints Mild cognitive impairment Vascular disease erogenous clinical entity with multiple aetiological factors...

...Karin Nilsson; Lars Gustafson; Björn Hultberg Background: Cobalamin/folate deficiency and vascular disease are prevalent in elderly subjects and may lead to mental symptoms, but may even more often influence the severity of other organic and non-organic mental diseases. In the present study, we...

... and its most important determinants (folate and cobalamin status and renal function), and the natriuretic peptide N-terminal-pro brain natriuretic peptide (NT-proBNP). The patients were classified into several groups of vascular disease according to the findings of brain imaging and presence of a history...

... and its most important determinants (serum folate and serum cobalamin, serum cystatin C and serum creatinine). The patients were divided into two groups according to the presence of vascular disease. Eighty-seven patients had concomitant vascular disease. We also analysed the natriuretic peptide N...

...K. Nägga; R. Rajani; E. Mårdh; K. Borch; S. Mårdh; J. Marcusson The prevalence of dementia disorders, cobalamin and/or folate deficiency as well as gastritis increases with age. To investigate whether there is an association between these conditions, plasma homocysteine (Hcy), serum methylmalonic...

... including serum CRP, age, blood folate, serum cobalamin, serum methylmalonic acid and serum creatinine showed that only blood folate (p < 0.001), age (p < 0.001), serum creatinine (p < 0.001), serum cobalamin (p < 0.001), and serum methylmalonic acid (p < 0.001) independently predicted plasma...

..., instructions or products referred to in the content or advertisements. Alzheimer’s disease Cardiovascular disease Cobalamin Creatinine Folate Homocysteine Vascular dementia Original Research Article Dement Geriatr Cogn Disord 2002;14:7 12 Received: August 2, 2001 Accepted after revision...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cobalamin Alzheimer’s disease Transcobalamin Haptocorrin Cobalamin analogues Ageing...

...Karin Nilsson; Lars Gustafson; Björn Hultberg The concentration of blood folates was decreased and the concentration of plasma homocysteine was increased in a psychogeriatric population, whereas the concentrations of methylmalonic acid or serum cobalamins were not changed compared with healthy...

... cobalamin balance, which is very common in elderly people. Cobalamin and folate are interdependent and essential components of the one-carbon metabolism. Another important component is methylenetetrahydrofolate reductase (MTHFR), the gene for which is also polymorphic. Thermolabile MTHFR (tMTHFR), a gene...