...Keiichi Kumai; Nobuko Kawabata; Kenichi Meguro; Junko Takada; Kei Nakamura; Satoshi Yamaguchi Introduction: The purpose of this study is to examine self-awareness of patients with Alzheimer disease (AD) regarding forgetfulness and physical status, with the goal of further psychological...

... and psychological symptoms of dementia (BPSD), and cognitive function. The ABC-DS can be administered easily and quickly and can clarify the severity of dementia and its changes over time. While the ABC-DS has been reported to be useful in Alzheimer disease (AD)-type dementia, it has not yet been studied in other...

...Kurt A. Jellinger Alzheimer disease (AD), the most common form of dementia, is a heterogenous disorder with various pathobiological subtypes. In addition to the 4 major subtypes based on the distribution of tau pathology and brain atrophy (typical, limbic predominant, hippocampal sparing...

...Angela Tian Hui Kwan; Saman Arfaie; Joseph Therriault; Pedro Rosa-Neto; Serge Gauthier Background: Alzheimer disease (AD) is a chronic neurodegenerative disorder with complex pathophysiology that affects over 50 million people worldwide. Most drug therapies, to date, have focused on targeting...

... by changes in behavior and personality, frequently leading to psychiatric misdiagnoses. On the other hand, substantial clinical overlap with other neurodegenerative diseases, such as Alzheimer disease (AD), further complicates the diagnostics. Objective: Our aim was to identify the main differences in early...

...Ting-Bin Chen; Shuo-Chun Weng; Yi-Yin Chou; Yu-Shan Lee; Chih-Kaung Liang; Chu-Sheng Lin; Tsuo-Hung Lan; Shih-Yi Lin; Yu-Te Lin Background: In Taiwan, the causes of death and related factors in the oldest old people with Alzheimer disease (AD) are not well characterized. We investigated the factors...

...Ales Bartos; Dan Fayette Background: The Czech version of the Montreal Cognitive Assessment (MoCA-CZ) and delayed recall of 5 words have not been validated in patients with mild cognitive impairment (MCI) due to Alzheimer disease (AD) and compared to norms of a large population. Method: The MoCA-CZ...

.... Methods: Language dysfunction in normal controls (NCs), and patients with Parkinson disease (PD), Parkinson disease dementia (PDD), dementia with Lewy bodies (DLB), or Alzheimer disease (AD) were analyzed and compared. Results: A total of 1,662 individuals were studied: 285 NCs, 157 PD patients, 161 PDD...

..., instructions or products referred to in the content or advertisements. Dementia Osteoarthritis Etoricoxib Diclofenac NSAIDs Alzheimer disease Osteoarthritis (OA), an age-related disorder [ 1 ], is the most common type of arthritis [ 2, 3 ] and the leading cause of disability in the elderly...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer disease Age of onset Cognitive reserve Bilingualism Cantonese Mandarin...

...Adam P. Mecca; Hannah R. Michalak; Julia W. McDonald; Emily C. Kemp; Erika A. Pugh; Melinda L. Becker; Marcia C. Mecca; Christopher H. van Dyck; The Alzheimer’s Disease Neuroimaging Initiative (ADNI) Background: We investigated the relationship between sleep disturbance and cognitive decline...

...Céline Borg; Zineb Bouazza; Marielle Godeau; Jean-Claude Getenet; Hanna Chainay Background: The present study examines whether the interaction between emotion and the enactment effect (body involvement) improves memory in people with Alzheimer disease (AD). Methods: Two experiments with drawings...

... effect, with the effect of treatment versus control twice as high for patients with Parkinson disease dementia/ dementia with Lewy bodies (2.11 MMSE points at 6 months) as for patients with Alzheimer disease/vascular dementia (0.91 MMSE points at 6 months). Key Messages: AChEIs demonstrate a modest...

... relationships between pathology and cognitive state prior to death. Discriminating the earliest signs of dementing disorders, such as Alzheimer disease (AD), is necessary to undertake early interventions and treatments. Methods: The neuropathological profile of brains donated from The University of Manchester...

...Julius S. Ngwa; Thomas V. Fungwe; Oyonumo Ntekim; Joanne S. Allard; Sheree M. Johnson; Chimene Castor; Lennox Graham; Sheeba Nadarajah; Richard F. Gillum; Thomas O. Obisesan; Alzheimer’s Disease Neuroimaging Initiative Background: It is increasingly evident that high blood pressure can promote...

...Achille E. Tchalla; Jean-Pierre Clément; Isabelle Saulnier; Betty Beaumatin; Florent Lachal; Caroline Gayot; Anaïs Bosetti; Iléana Desormais; Anaïck Perrochon; Pierre-Marie Preux; Philippe Couratier; Thierry Dantoine Background/Aims: Alzheimer disease (AD) is particularly devastating, with no cure...

...Felicia C. Goldstein; Aaron Milloy; David W. Loring; for the Alzheimer’s Disease Neuroimaging Initiative Background/Aims: The aim of this paper was to evaluate the incremental validity of the Montreal Cognitive Assessment (MoCA) index scores and the MoCA total score in differentiating individuals...

...% of the participants with probable Alzheimer disease were treated with acetylcholinesterase inhibitors. In 2011, we observed a significant improvement in primary diagnostics and therapy. 66.9% of the cases of dementia were adequately evaluated, and 52.1% were adequately treated. Conclusion: Cognitive deficit...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer disease Apolipoprotein E Microglia Perivascular drainage...

... is released by endothelium and is regulated by proangiogenic and proinflammatory cytokines, may have a role in the pathophysiology of Alzheimer disease (AD). The aim of this study was to evaluate the relationship between serum endocan levels and AD. Methods: A total of 134 patients (47 AD, 42 amnestic mild...