...Oskar H. Sommer; Øyvind Kirkevold; Milada Cvancarova; Knut Engedal Background: Agitation and aggression are prevalent in dementia and put heavy strains on caregivers. Validated assessment tools measuring these symptoms are required to evaluate patients before therapy and during the follow-up period...

... agitation and aggression. Prospective, well-designed trials are warranted to evaluate the efficacy of memantine in patients with significant behavioral symptoms. 16 12 2008 5 2 2009 © 2009 S. Karger AG, Basel 2009 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

...Oskar H. Sommer; Olav Aga; Milada Cvancarova; Inge C. Olsen; Geir Selbaek; Knut Engedal Background/Aims: To evaluate the efficacy of oxcarbazepine (OXC) in the treatment of agitation and aggression in patients with Alzheimer’s disease, vascular dementia or both. Methods: This is an 8-week...

... and presence of irritability and between the 10-repeat allele and aberrant motor behaviour (AMB); however, these do not remain significant after correction for multiple testing. No associations were observed with delusions, hallucinations, depression, agitation/aggression or elation. Conclusion: Our data...

... of serotonergic involvement (delusions, hallucinations, depression, anxiety, agitation/aggression and irritability) were related to genotype and allele frequencies of the linked polymorphic region and variable number tandem repeat variants. Results: Analysis revealed significant relationships between the linked...

...Nathan Herrmann; Krista L. Lanctôt; Lana S. Rothenburg; Goran Eryavec Background/Aims: To assess the efficacy and tolerability of valproate for the treatment of agitation and aggression in moderate-to-severe Alzheimer’s disease (AD). Methods: This was a randomized, double-blind, placebo-controlled...

... Antisocial Aggression Abstract Background: It is not understood why some patients with frontotemporal dementia (FTD) manifest sociopathic behavior. Objective: To examine the prevalence and characteristics of sociopathic behavior in FTD patients as compared to those with Alzheimer s disease (AD). Methods...

... with AD and delusional/aggressive symptoms of AD in Korean samples of 65 patients and 43 controls. The 5-HTTLPR polymorphism was neither associated with AD nor with delusional/aggressive symptoms of AD. It was suggested that phenotypic expression of the 5-HTTLPR polymorphism might be varied according...

... patients to agitation by exaggerating behavioral responses to many types of coexisting psychopathology or environmental provocations. Agitation Frontal lobe Alzheimer’s disease Neuropsychiatric Inventory Disinhibition Psychosis Depression Aggression Original Research Article Dement Geriatr...

... and dementia variables. There was no significant association between patient delusions, hallucinations, or depression and caregiver burden or depression. Agitation, particularly physical aggression, may impact caregivers even more than does the cognitive status of the demented patient. 19 12 1997...