Abstract
Background: Intrinsic capacity, a concept proposed by the World Health Organization, includes multidimensions to better understand older adults’ health conditions for successful healthy aging. One of the key dimensions of intrinsic capacity is cognition. The present study aimed to examine if the cognitive test in Integrated Care for Older People Screening Tool for Taiwanese (ICOPES-TW) is a suitable instrument for screening cognition impairment. Methods: Older adults from community or medical center settings in Tainan were recruited (n = 553; mean ± SD age = 75.80 ± 8.32; 60.8% females). All participants were administered the ICOPES-TW cognitive test, the Mini-Mental State Examination (MMSE), Lawton Instrumental Activities of Daily Living (IADL), and Barthel Index (BI) in an in-person interview conducted by a well-trained research assistant. Results: The ICOPES-TW cognitive test was highly correlated with the MMSE total score (r = −0.752) and moderately correlated with IADL (r = −0.426) and BI scores (r = −0.390). When using a cutoff score of 1 for the ICOPES-TW cognitive test, its accuracy to identify cognitive impairment defined by the MMSE was 60% (sensitivity = 0.98, specificity = 0.41). When using cutoff score of 2, the accuracy was 83% (sensitivity = 0.69, specificity = 0.90). Moreover, the ICOPES-TW cognitive test had similar properties to the MMSE in terms of known-group validity (distinguishing different age and educational level groups). Conclusions: Using ICOPES-TW cognitive test with appropriate cutoff point in different healthcare settings could help providers and researchers quickly identify if an older adult has a cognitive impairment. However, the screening ability of ICOPES-TW cognitive test was deemed fair but future studies are recommended to help improve it.
Journal Section:
Research Article
References
1.
López-Ortiz
S
, Lista
S
, Peñín-Grandes
S
, Pinto-Fraga
J
, Valenzuela
PL
, Nisticò
R
, et al. Defining and assessing intrinsic capacity in older people: a systematic review and a proposed scoring system
. Ageing Res Rev
. 2022
;79
:101640
. 2.
Gonzalez-Bautista
E
, Andrieu
S
, Gutierrez-Robledo
LM
, Garcia-Chanes
RE
, de Souto Barreto
P
. In the quest of a standard index of intrinsic capacity. A critical literature review
. J Nutr Health Aging
. 2020
;24
(9
):959
–65
. 3.
Beard
JR
, Jotheeswaran
AT
, Cesari
M
, Araujo de Carvalho
I
. The structure and predictive value of intrinsic capacity in a longitudinal study of ageing
. BMJ Open
. 2019
;9
(11
):e026119
. 4.
Beard
JR
, Si
Y
, Liu
Z
, Chenoweth
L
, Hanewald
K
. Intrinsic capacity: Validation of a new WHO concept for healthy aging in a longitudinal Chinese study
. J Gerontol A Biol Sci Med Sci
. 2022
;77
(1
):94
–100
. 5.
Chen
YJ
, Kukreti
S
, Yang
HL
, Liu
CC
, Yeh
YC
, Fung
XCC
, et al. Psychometric properties of instruments assessing intrinsic capacity: a systematic review
. Asian J Soc Health Behav
. 2023
;6
(4
):141
–55
. 6.
George
PP
, Lun
P
, Ong
SP
, Lim
WS
. A rapid review of the measurement of intrinsic capacity in older adults
. J Nutr Health Aging
. 2021
;25
(6
):774
–82
. 7.
Gutierrez-Robledo
LM
, Garcia-Chanes
RE
, Gonzalez-Bautista
E
, Rosas-Carrasco
O
. Validation of two intrinsic capacity scales and its relationship with frailty and other outcomes in Mexican community-dwelling older adults
. J Nutr Health Aging
. 2021
;25
(1
):33
–40
. 8.
Leung
AYM
, Su
JJ
, Lee
ESH
, Fung
JTS
, Molassiotis
A
. Intrinsic capacity of older people in the community using WHO Integrated Care for Older People (ICOPE) framework: a cross-sectional study
. BMC Geriatr
. 2022
;22
(1
):304
. 9.
Ma
L
, Chhetri
JK
, Zhang
Y
, Liu
P
, Chen
Y
, Li
Y
, et al. Integrated care for older people screening tool for measuring intrinsic capacity: preliminary findings from ICOPE pilot in China
. Front Med
. 2020
;7
:576079
. 10.
Yu
R
, Amuthavalli Thiyagarajan
J
, Leung
J
, Lu
Z
, Kwok
T
, Woo
J
. Validation of the construct of intrinsic capacity in a longitudinal Chinese cohort
. J Nutr Health Aging
. 2021
;25
(6
):808
–15
. 11.
Chang
YH
, Lin
CY
, Chou
YT
, Chen
HY
, Su
HC
, Wu
YL
, et al. A simple scoring algorithm based on intrinsic capacity for functional ability in community-dwelling older adults in Taiwan
. BMC Geriatr
. 2024
;24
(1
):370
. 12.
Su
HC
, Liu
C
, Chen
HY
, Wu
YL
, Griffiths
MD
, Li
CY
, et al. Assessing intrinsic capacity in taiwan: initial psychometric properties of the integrated care for older people screening tool for Taiwanese (ICOPES-TW)
. BMC Geriatr
. 2024
;24
(1
):477
. 13.
Ting
CW
, Chang
CC
, Yeh
PC
. Data analysis of integrated care for old people (ICOPE) screening and evaluation: example from a clinic in the northern taiwan
. Formosan J Physical Therapy
. 2022
;47
(2
):141
–2
.14.
Su
JA
, Chang
CC
, Wang
HM
, Chen
KJ
, Yang
YH
, Lin
CY
. Antidepressant treatment and mortality risk in patients with dementia and depression: a nationwide population cohort study in Taiwan
. Ther Adv Chronic Dis
. 2019
;10
:2040622319853719
–4
. 15.
Su
JA
, Chang
CC
, Yang
YH
, Chen
KJ
, Li
YP
, Lin
CY
. Risk of incident dementia in late-life depression treated with antidepressants: a nationwide population cohort study
. J Psychopharmacol
. 2020
;34
(10
):1134
–42
. 16.
Chen
YJ
, Su
JA
, Chen
JS
, Liu
CH
, Griffiths
MD
, Tsai
HC
, et al. Examining the association between neuropsychiatric symptoms among people with dementia and caregiver mental health: are caregiver burden and affiliate stigma mediators
. BMC Geriatr
. 2023
;23
(1
):27
. 17.
Hu
YL
, Chang
CC
, Lee
CH
, Liu
CH
, Chen
YJ
, Su
JA
, et al. Associations between affiliate stigma and quality of life among caregivers of individuals with dementia: mediated roles of caregiving burden and psychological distress
. Asian J Social Health Behav
. 2023
;6
(2
):64
–71
. 18.
Lin
CY
, Shih
PY
, Ku
LJ
. Activities of daily living function and neuropsychiatric symptoms of people with dementia and caregiver burden: the mediating role of caregiving hours
. Arch Gerontol Geriatr
. 2019
;81
:25
–30
. 19.
Folstein
MF
, Folstein
SE
, McHugh
PR
. Mini-mental state examination (MMSE) [database record]
. APA PsycTests
; 1975
.20.
Mahoney
FI
, Barthel
DW
. Functional evaluation: the Barthel index
. Md State Med J
. 1965
;14
:61
–5
.21.
Graf
C
. The Lawton instrumental activities of daily living scale
. Am J Nurs
. 2008
;108
(4
):52
–63
. 22.
Folstein
MF
, Folstein
SE
, McHugh
PR
. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician
. J Psychiatr Res
. 1975
;12
(3
):189
–98
. 23.
Guo
NW
, Liu
HC
, Wong
PF
. Chinese version and norms of the mini-mental state examination
. Taiwan Acad Phys Med Rehabil
. 1988
;16
(1
):52
–9
. 24.
Arevalo-Rodriguez
I
, Smailagic
N
, Roqué-Figuls
M
, Ciapponi
A
, Sanchez-Perez
E
, Giannakou
A
, et al. Mini-Mental State Examination (MMSE) for the early detection of dementia in people with mild cognitive impairment (MCI)
. Cochrane Database Syst Rev
. 2021
;7
(7
):CD010783
. 25.
Nahm
FS
. Receiver operating characteristic curve: overview and practical use for clinicians
. Korean J Anesthesiol
. 2022
;75
(1
):25
–36
. 26.
Polo
TC
, Miot
HA
. Use of ROC curves in clinical and experimental studies
. J Vasc Bras
. 2020
;19
:e20200186
. 27.
Lin
CY
, Luh
WM
, Yang
AL
, Su
CT
, Wang
JD
, Ma
HI
. Psychometric properties and gender invariance of the Chinese version of the self-report Pediatric Quality of Life Inventory Version 4.0: short form is acceptable
. Qual Life Res
. 2012
;21
(1
):177
–82
. 28.
Bandalos
DL
. Measurement theory and applications for the social sciences
. New York
: The Guilford Press
; 2018
.29.
Palmieri
JW
, Agardh
A
, Östergren
PO
. Validating a modified instrument for measuring Demand-Control-Support among students at a large university in southern Sweden
. Glob Health Action
. 2023
;16
(1
):2226913
. 30.
Šimundić
AM
. Measures of diagnostic accuracy: basic definitions
. EJIFCC
. 2009
;19
(4
):203
–11
.31.
Rojano I Luque
X
, Blancafort-Alias
S
, Prat Casanovas
S
, Forné
S
, Martín Vergara
N
, Fabregat Povill
P
, et al. Identification of decreased intrinsic capacity: performance of diagnostic measures of the ICOPE Screening tool in community dwelling older people in the VIMCI study
. BMC Geriatr
. 2023
;23
(1
):106
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