Aims: Inhibition associated with perception has been implicated in sensory integration processes for balance when sensory conflict occurs. The current study examines the associations of three measures of inhibition (perceptual inhibition, motor inhibition, and Stroop interference) with standing balance under sensory conflict conditions in younger and older adults. Methods: Perceptual inhibition, motor inhibition, and Stroop interference were measured in younger and older subjects. Standing balance under conditions of sensory conflict was evaluated using a modified dynamic posturography protocol. Correlative analysis was performed to examine the associations between the inhibition measures and sway. Results: In older adults only, perceptual inhibition was correlated with sway when sensory conflict was present. Stroop interference and motor inhibition were not significantly correlated with sway under any posturography conditions. Conclusion: Measures of perceptual inhibition are associated with reduced sensory integration capability for balance during sensory conflict conditions in older adults.

1.
Kearney
FC
,
Harwood
RH
,
Gladman
JR
,
Lincoln
N
,
Masud
T
.
The relationship between executive function and falls and gait abnormalities in older adults: a systematic review
.
Dement Geriatr Cogn Disord
.
2013
;
36
(
1-2
):
20
35
.
[PubMed]
1420-8008
2.
Herman
T
,
Mirelman
A
,
Giladi
N
,
Schweiger
A
,
Hausdorff
JM
.
Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and falling
.
J Gerontol A Biol Sci Med Sci
.
2010
Oct
;
65
(
10
):
1086
92
.
[PubMed]
1079-5006
3.
Holtzer
R
,
Friedman
R
,
Lipton
RB
,
Katz
M
,
Xue
X
,
Verghese
J
.
The relationship between specific cognitive functions and falls in aging
.
Neuropsychology
.
2007
Sep
;
21
(
5
):
540
8
.
[PubMed]
0894-4105
4.
Mirelman
A
,
Herman
T
,
Brozgol
M
,
Dorfman
M
,
Sprecher
E
,
Schweiger
A
, et al.
Executive function and falls in older adults: new findings from a five-year prospective study link fall risk to cognition
.
PLoS One
.
2012
;
7
(
6
):
e40297
.
[PubMed]
1932-6203
5.
Taylor
ME
,
Lord
SR
,
Delbaere
K
,
Kurrle
SE
,
Mikolaizak
AS
,
Close
JC
:
Reaction Time and Postural Sway Modify the Effect of Executive Function on Risk of Falls in Older People with Mild to Moderate Cognitive Impairment.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
2017
;25:397-406.
6.
Sheridan
PL
,
Hausdorff
JM
.
The role of higher-level cognitive function in gait: executive dysfunction contributes to fall risk in Alzheimer’s disease
.
Dement Geriatr Cogn Disord
.
2007
;
24
(
2
):
125
37
.
[PubMed]
1420-8008
7.
Yogev-Seligmann
G
,
Hausdorff
JM
,
Giladi
N
.
The role of executive function and attention in gait
.
Mov Disord
.
2008
Feb
;
23
(
3
):
329
42
.
[PubMed]
0885-3185
8.
Allali
G
,
Assal
F
,
Kressig
RW
,
Dubost
V
,
Herrmann
FR
,
Beauchet
O
.
Impact of impaired executive function on gait stability
.
Dement Geriatr Cogn Disord
.
2008
;
26
(
4
):
364
9
.
[PubMed]
1420-8008
9.
Beauchet
O
,
Launay
CP
,
Fantino
B
,
Annweiler
C
,
Allali
G
.
Episodic memory and executive function impairments in non-demented older adults: which are the respective and combined effects on gait performances?
Age (Dordr)
.
2015
Aug
;
37
(
4
):
9812
.
[PubMed]
2452-0756
10.
Muir-Hunter
SW
,
Clark
J
,
McLean
S
,
Pedlow
S
,
Van Hemmen
A
,
Montero Odasso
M
, et al.
Identifying balance and fall risk in community-dwelling older women: the effect of executive function on postural control
.
Physiother Can
.
2014
;
66
(
2
):
179
86
.
[PubMed]
0300-0508
11.
Redfern
MS
,
Jennings
JR
,
Mendelson
D
,
Nebes
RD
.
Perceptual inhibition is associated with sensory integration in standing postural control among older adults
.
J Gerontol B Psychol Sci Soc Sci
.
2009
Sep
;
64
(
5
):
569
76
.
[PubMed]
1079-5014
12.
Wecker
NS
,
Kramer
JH
,
Wisniewski
A
,
Delis
DC
,
Kaplan
E
.
Age effects on executive ability
.
Neuropsychology
.
2000
Jul
;
14
(
3
):
409
14
.
[PubMed]
0894-4105
13.
Anstey
KJ
,
Wood
J
,
Kerr
G
,
Caldwell
H
,
Lord
SR
.
Different cognitive profiles for single compared with recurrent fallers without dementia
.
Neuropsychology
.
2009
Jul
;
23
(
4
):
500
8
.
[PubMed]
0894-4105
14.
Schoene
D
,
Delbaere
K
,
Lord
SR
.
Impaired Response Selection During Stepping Predicts Falls in Older People-A Cohort Study
.
J Am Med Dir Assoc
.
2017
Aug
;
18
(
8
):
719
25
.
[PubMed]
1525-8610
15.
Schoene
D
,
Smith
ST
,
Davies
TA
,
Delbaere
K
,
Lord
SR
.
A Stroop Stepping Test (SST) using low-cost computer game technology discriminates between older fallers and non-fallers
.
Age Ageing
.
2014
Mar
;
43
(
2
):
285
9
.
[PubMed]
0002-0729
16.
Redfern
MS
,
Jennings
JR
,
Martin
C
,
Furman
JM
.
Attention influences sensory integration for postural control in older adults
.
Gait Posture
.
2001
Dec
;
14
(
3
):
211
6
.
[PubMed]
0966-6362
17.
Jensen
AR
,
Rohwer
WD
 Jr
.
The Stroop color-word test: a review
.
Acta Psychol (Amst)
.
1966
;
25
(
1
):
36
93
.
[PubMed]
0001-6918
18.
Chen
TY
,
Peronto
CL
,
Edwards
JD
.
Cognitive function as a prospective predictor of falls
.
J Gerontol B Psychol Sci Soc Sci
.
2012
Nov
;
67
(
6
):
720
8
.
[PubMed]
1079-5014
19.
Saverino
A
,
Waller
D
,
Rantell
K
,
Parry
R
,
Moriarty
A
,
Playford
ED
.
The Role of Cognitive Factors in Predicting Balance and Fall Risk in a Neuro-Rehabilitation Setting
.
PLoS One
.
2016
Apr
;
11
(
4
):
e0153469
.
[PubMed]
1932-6203
20.
Nassauer
KW
,
Halperin
JM
.
Dissociation of perceptual and motor inhibition processes through the use of novel computerized conflict tasks
.
J Int Neuropsychol Soc
.
2003
Jan
;
9
(
1
):
25
30
.
[PubMed]
1355-6177
21.
Jennings
JR
,
Mendelson
DN
,
Redfern
MS
,
Nebes
RD
.
Detecting age differences in resistance to perceptual and motor interference
.
Exp Aging Res
.
2011
Mar
;
37
(
2
):
179
97
.
[PubMed]
0361-073X
22.
Germain
S
,
Collette
F
.
Dissociation of perceptual and motor inhibitory processes in young and elderly participants using the Simon task
.
J Int Neuropsychol Soc
.
2008
Nov
;
14
(
6
):
1014
21
.
[PubMed]
1355-6177
23.
Stawarczyk
D
,
Grandjean
J
,
Salmon
E
,
Collette
F
.
Perceptual and motor inhibitory abilities in normal aging and Alzheimer disease (AD): a preliminary study
.
Arch Gerontol Geriatr
.
2012
Mar-Apr
;
54
(
2
):
e152
61
.
[PubMed]
0167-4943
24.
Furman
JM
,
Cass
SP
. Laboratory testing. In:
Baloh
RW
,
Halmagyi
M
, editors
.
Electronystagmography and rotational testing Disorders of the vestibular system
.
New York (NY)
:
Oxford Press
;
1996
.
25.
Martina
IS
,
van Koningsveld
R
,
Schmitz
PI
,
van der Meché
FG
,
van Doorn
PA
.
Measuring vibration threshold with a graduated tuning fork in normal aging and in patients with polyneuropathy. European Inflammatory Neuropathy Cause and Treatment (INCAT) group
.
J Neurol Neurosurg Psychiatry
.
1998
Nov
;
65
(
5
):
743
7
.
[PubMed]
0022-3050
26.
Holewski
JJ
,
Stess
RM
,
Graf
PM
,
Grunfeld
C
.
Aesthesiometry: quantification of cutaneous pressure sensation in diabetic peripheral neuropathy
.
J Rehabil Res Dev
.
1988
;
25
(
2
):
1
10
.
[PubMed]
0748-7711
27.
Mendelson
DN
,
Redfern
MS
,
Nebes
RD
,
Richard Jennings
J
.
Inhibitory processes relate differently to balance/reaction time dual tasks in young and older adults
.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
.
2010
Jan
;
17
(
1
):
1
18
.
[PubMed]
1382-5585
28.
Nashner
LM
,
Black
FO
,
Wall
C
 3rd
.
Adaptation to altered support and visual conditions during stance: patients with vestibular deficits
.
J Neurosci
.
1982
May
;
2
(
5
):
536
44
.
[PubMed]
0270-6474
29.
Woollacott
MH
,
Shumway-Cook
A
,
Nashner
LM
.
Aging and posture control: changes in sensory organization and muscular coordination
.
Int J Aging Hum Dev
.
1986
;
23
(
2
):
97
114
.
[PubMed]
0091-4150
30.
Manchester
D
,
Woollacott
M
,
Zederbauer-Hylton
N
,
Marin
O
.
Visual, vestibular and somatosensory contributions to balance control in the older adult
.
J Gerontol
.
1989
Jul
;
44
(
4
):
M118
27
.
[PubMed]
0022-1422
31.
Horak
FB
,
Shupert
CL
,
Mirka
A
.
Components of postural dyscontrol in the elderly: a review
.
Neurobiol Aging
.
1989
Nov-Dec
;
10
(
6
):
727
38
.
[PubMed]
0197-4580
32.
Borger
LL
,
Whitney
SL
,
Redfern
MS
,
Furman
JM
:
The influence of dynamic visual environments on postural sway in the elderly.
Journal of vestibular research : equilibrium & orientation
1999
;9:197-205.
33.
Lord
SR
,
Clark
RD
,
Webster
IW
.
Visual acuity and contrast sensitivity in relation to falls in an elderly population
.
Age Ageing
.
1991
May
;
20
(
3
):
175
81
.
[PubMed]
0002-0729
34.
Fuhrman
SI
,
Redfern
MS
,
Jennings
JR
,
Furman
JM
: Interference between postural control and spatial vs. non-spatial auditory reaction time tasks in older adults. Journal of vestibular research : equilibrium & orientation
2015
;25:47-55.
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