... Risk prediction Dementia Alzheimer disease Incidence Statistical model RCUK As strategies to tackle the global burden of disease associated with dementia move towards a greater focus on primary prevention, in particular risk reduction, the identification of individuals at high...

... of infodemiology. Methods: Using Google Trends, data on global search queries for Alzheimer disease (AD) between January 2004 and April 2021 were analyzed. The relationship between online interest, as reflected by search volume index (SVI), and measures of disease burden, namely prevalence, deaths, and disability...

... phase of Alzheimer disease. These complex but interesting issues lead to contradictory speculations of possible effects of ractopamine residue in meat on Alzheimer disease. Hypotheses derived from this review surely deserve carefully designed laboratory investigations and clinical studies in the future...

...Mayuka Oki; Miyuki Matsumoto; Yukiko Yoshikawa; Mitsuko Fukushima; Akira Nagasawa; Tomokazu Takakura; Yukiko Suzuki Aim: This study aimed to determine the main risk factors for falls in patients with Alzheimer disease (AD) by comparing balance, cognition, and visuospatial ability between those who...

... biomarkers, and sleep symptoms in elderly participants, most of whom had dementia. Methods: One-hundred twenty-six adults (mean age 66.2 ± 8.4 years) were recruited from the Emory Cognitive Clinic. Diagnoses were Alzheimer disease (AD; n = 60), frontotemporal dementia (FTD; n = 21), and dementia with Lewy...

...Behnam Honarvar; Elahe Khaksar; Fatemeh Jafari; Mohammad Hassan Zahedroozegar; Sanaz Amiri Background/Aims: Quality of life (QOL) and Alzheimer disease (AD) among older people have been recognized as public health challenges. Here, we investigated the association between QOL and AD in the elders...

... (bvFTD) differs from that of Alzheimer disease (AD), with major impairments in behavioral functions in bvFTD and cognitive impairment in AD. Both behavioral disturbances in bvFTD and cognitive impairment in AD contribute to caregiver burden. Objective: To investigate the impact of home confinement during...

... recognition (SPR) method in patients with cognitive impairment. We compared the differential diagnostic ability of SPR to visual EEG analysis. Correlation between SPR findings and cerebrospinal fluid (CSF) Alzheimer disease (AD) biomarkers were evaluated. Methods: It is a multicenter cohort study involving...

...Alberto Mimenza-Alvarado; Sara G. Aguilar-Navarro; Sara Yeverino-Castro; César Mendoza-Franco; José Alberto Ávila-Funes; Gustavo C. Román Introduction: Cerebral small-vessel disease (SVD) represents the most frequent type of vascular brain lesions, often coexisting with Alzheimer disease (AD...

...Hossein Pakdaman; Koroush Gharagozli; Mehdi Abbasi; Ali Sobhanian; Ali Bakhshandehpour; Farzad Ashrafi; Mitra Khalilzad; Ali Amini Harandi Background and Aim: Alzheimer disease (AD) is the most common cause of dementia. Currently, there is no disease-modifying therapy for AD. We aimed to evaluate...

...Ali Tafazzoli; Anuraag Kansal; Peter Lockwood; Charles Petrie; Alexandra Barsdorf Background/Aims: Few studies have modeled individual Neuropsychiatric Inventory (NPI) symptom scores for Alzheimer disease (AD) patients and assessed the value of therapeutic interventions that can potentially impact...

...Noriko Ogama; Takashi Sakurai; Naoki Saji; Toshiharu Nakai; Shumpei Niida; Kenji Toba; Hiroyuki Umegaki; Masafumi Kuzuya Background/Aims: Behavioral and psychological symptoms of dementia (BPSD) are exhibited in most patients with Alzheimer disease (AD). Although white matter hyperintensity (WMH...

...: The subjects were patients with mild to moderate Alzheimer disease treated with either rivastigmine patch ( n = 11) or donepezil ( n = 11) for 6 months. Before and after treatment, we evaluated appetite (0, decreased; 1, slightly decreased; 2, normal; 3, slightly increased; 4, increased), cognitive function...

...Flavia Mayer; Alessandra Di Pucchio; Eleonora Lacorte; Ilaria Bacigalupo; Fabrizio Marzolini; Gianluigi Ferrante; Valentina Minardi; Maria Masocco; Marco Canevelli; Teresa Di Fiandra; Nicola Vanacore Background: Up to 53.7% of all cases of dementia are assumed to be due to Alzheimer disease (AD...

...Satoshi Hayashi; Seishi Terada; Etsuko Oshima; Shuhei Sato; Kairi Kurisu; Shintaro Takenoshita; Osamu Yokota; Norihito Yamada Objective: Among many cognitive function deficits, memory impairment is an initial and cardinal symptom in Alzheimer disease (AD). In most cases, verbal and visual memory...

... and pathophysiologically different from Alzheimer disease (AD) and vascular dementia. We determined whether skeletal muscle strength, quality, and mass decrease in individuals with DrD. Methods: We evaluated grip and knee extension strength, muscle mass, and gait speed in 106 patients with probable AD and without type 2...

...Gideon A. Caplan; JIan Tai; Fazrul Mohd Hanizan; Catherine L. McVeigh; Mark A. Hill; Anne Poljak Background/Aims: Delirium and the apolipoprotein E ε4 allele are risk factors for late-onset Alzheimer disease (LOAD), but the connection is unclear. We looked for an association. Methods: Inpatients...

...Sevki Sahin; Tugba Okluoglu Önal; Nilgun Cinar; Meral Bozdemir; Rahmi Çubuk; Sibel Karsidag Background and Aim: Depressive pseudodementia (DPD) is a condition which may develop secondary to depression. The aim of this study was to contribute to the differential diagnosis between Alzheimer disease...

...Yasuhiro Nagahama; Tomoko Okina; Norio Suzuki Background/Aims: To examine the influence of age on neuropsychological performances in dementia with Lewy bodies (DLB) and Alzheimer disease (AD) patients. Methods: We examined memory, executive, and visuo-constructional performances in 202 DLB patients...

...Niko M. Perttila; Hannareeta Öhman; Timo E. Strandberg; Hannu Kautiainen; Minna Raivio; Marja-Liisa Laakkonen; Niina Savikko; Reijo S. Tilvis; Kaisu H. Pitkala Background: People with dementia are at high risk for falls. However, little is known of the features causing falls in Alzheimer disease...