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Keywords: Transplantation
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Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (1-2): 107–114.
Published Online: 01 February 2017
...C.J. Hawkey Both autologous and allogeneic haemopoietic stem cell transplantation (HSCT) have been tried in Crohn's disease (CD). In allogeneic HSCT, the host bone marrow is ablated and replaced by bone marrow from a donor. This substitution of a genetically different bone marrow is effective...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2013) 31 (1): 155–163.
Published Online: 17 June 2013
... transplantation candidates and the issue of withdrawal. Alternative immunosuppressive drugs such as transplantation immunosuppressants have been administered and reported in small series. In an attempt to optimize side effect management, a recent large multicenter prospective treatment trial suggests...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2013) 30 (Suppl. 3): 134–139.
Published Online: 03 January 2013
...C.J. Hawkey Background: The Autologous Stem Cell Transplantation International Crohn’s Disease (ASTIC) trial is a randomised controlled evaluation of the proposition that immunoablation and haemopoietic stem cell transplantation improves the course of Crohn’s disease. Recruitment of all 48 patients...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (Suppl. 1): 11–19.
Published Online: 11 October 2012
... the greatest challenges in treating AIH. Alternative immunosuppressive drugs have been tested in small series and have included commonly used transplant immunosuppressants, albeit with mixed results and many unwanted drug side effects. A recent large multicenter prospective treatment trial suggests...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (4): 391–401.
Published Online: 30 August 2011
...Volker Benseler; Szun Szun Tay; David G. Bowen; Patrick Bertolino Unlike other solid organs, liver transplants are spontaneously accepted in a wide range of animal models. In the clinic, transplanted livers also display privileged immunological properties allowing weaning of immunosuppression...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2010) 28 (1): 45–50.
Published Online: 07 May 2010
...Thomas Giese; Claudia Sommerer; Martin Zeier; Stefan Meuer Long-term immunosuppression causes a significantly increased risk for the development of malignancies in transplanted patients. A link between immunosuppression and incidence of cancer is well documented and involves the effect...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (1996) 14 (Suppl. 1): 30–39.
Published Online: 04 November 2008
... and decreased myoinositol. The specific association with HE is proven by clinical studies in patients with cirrhosis, overt and subclinical HE, by the appearance of the same changes after transjugular intrahepatic portasystemic shunt, and by their complete reversal by liver transplantation. The importance...