... exposed to PPIs and those not exposed, from the inception of the databases to April 2024. The primary adverse outcomes analyzed included hospitalization and surgery. Results: Five studies, encompassing nearly 100,000 subjects, were included in this meta-analysis. The findings indicated that IBD patients...

... to in the content or advertisements. 2024 Acute diverticulitis Emergency room Diagnostic and therapeutic assistance pathway Surgery Hospital stay The diverticula are extroflexions of the colonic wall, which are formed in “ loci minoris resistentiae ” of the colon, that generally correspond...

..., instructions or products referred to in the content or advertisements. 2023 Chronic pancreatitis Patient information EQIP tool Quality Tool Surgery Online health information Internet Health-seeking Behaviour Review The internet has become the primary source of information for both...

.... In the subgroup analysis, the pooled HR was 0.38 (95% CI, 0.24–0.59) for OS in H. pylori -positive patients who received surgery combined with chemotherapy. The pooled HR for disease-free survival was 0.74 (95% CI, 0.63–0.8) and 0.41 (95% CI, 0.26–0.65) in patients who received surgery combined with chemotherapy...

... subjects (12%). Other presentations included 2 cases (1.1%) of dyspepsia, 2 of dysphagia (1.1%), 2 of diarrhea (1.1%), and 1 case of dyspnea (0.6%). In 1 case (0.6%), the only finding was anemia. There was one gastric perforation (0.6%) that led to emergent surgery. One patient presented with symptoms...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Rectal cancer Rectum Recurrence Surgery Adenocarcinoma of the rectum, which arises from epithelial cells...

...Jose Luis Rueda García; Cristina Suárez-Ferrer; Joaquín Poza Cordón; Eduardo Martín-Arranz; María Sánchez Azofra; Laura García Ramírez; Jesús Noci; María Dolores Martín-Arranz Bakground and Aim: Predictors of the need for surgery in sticturing Crohn’s disease (SCD) are lacking. Bowel ultrasound (US...

... adopted in high volume centers with high success rates (up to 98%). Jet, positive resection margins after ESD, LVI and poor tumor differentiation carry high metastatic potential, therefore advocating surgery. Limited resections and cooperative laparoscopic endoscopic approach may be implemented in cases...

... invasive than surgical treatment, associated with shorter hospital stay and lower cost. According to the current clinical practice, surgery has been accepted as standard therapeutic approach in familial adenomatous polyposis patients with severe polyposis or DA not amenable to endoscopic resection. Key...

... diseases, including ulcerative colitis (UC) and Crohn's disease (CD), is quite varied and still quite unpredictable. Key Messages: According to earlier studies, up to 60% of patients undergo at least one operation after 10 years of CD duration. Newer cohorts report lower cumulative probability of surgery...

... to 20%. In summary, ANP is managed primarily by a conservative therapy. In case of infected necrosis, interventional and minimally invasive approaches are the therapy of choice. Open surgery should be considered for patients deteriorating despite other measures and should be postponed as long...

... within a year post surgery. The mucosa just above the site of the intestinal anastomosis is at particularly high risk of relapse. Prophylactic medical therapy to prevent recurrence has been shown to be effective with a variety of medications, but the recurrence rate remains high, demanding that a better...

... approach. Success rates for percutaneous drainage in the literature vary from 74 to 100%, and it is considered to be a relatively safe procedure. It has been reported that surgery can be avoided after successful percutaneous drainage in a variable number of patients (14-85%). If sepsis is controlled, CD...

... tract carcinoma Cholangiocarcinoma Surgery Neoadjuvant therapy Adjuvant therapy National Institutes of Health (NIH) 10.13039/100000002 Cholangiocarcinoma (CC) is a rare tumour of cholangiocytes (epithelia of the biliary tract) [ 1 ] with an incidence in the UK of approximately 1...

...Marla Dubinsky Considerable debate exists as to whether the risk of complications and need for surgery has truly decreased in Crohn's disease (CD) over time. A recent systematic review and meta-analysis reported that after the year 2000, the surgical rates at 1, 5 and 10 years have significantly...

...Alastair Forbes In general, the patient receiving surgery for Crohn's disease (CD) makes an uncomplicated recovery with a speed consistent with the degree of surgical ‘insult' - which in these days of laparoscopic approach and minimalist resection often means very rapidly indeed. However...

...Anja U. van Lent; Geert R. D'Haens The course of Crohn's disease (CD) is unpredictable and potentially destructive. The percentage of patients requiring surgery at some stage in their disease accumulates to over 70%. After resection of the affected intestine, reappearance of CD occurs...

...Gianluca M. Sampietro; Silvia Casiraghi; Diego Foschi Surgery is a part of the clinical history of patients with Crohn's disease (CD) since nearly all the patients receive at least one surgical procedure. The main indication for surgery is obstruction, but 50-60% of patients present a concomitant...

... expectation of in-hospital mortality rates of 2-4% in high-volume centers. Most patients with regional cancers (T2-4 N0-3) are recommended for neoadjuvant therapy, which most commonly involves radiochemotherapy. Some centers have proposed treating with definitive chemoradiation and reserving surgery...

.... Nonresponders to H. pylori eradication are referred to radiation with a curative intention in stages I and II. The rare cases of MALT lymphoma of stage III and IV should be treated by chemotherapy. Surgery no longer plays a role in the therapy of gastric MALT lymphoma except for very rare complications...