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Keywords: Proton pump inhibitors
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Subject Area:
Gastroenterology
Dig Dis (2023) 41 (1): 10–16.
Published Online: 31 January 2023
... for ≥2 days in the past week among those taking PPI daily. Another secondary outcome was to assess the risk factors associated with GORD prevalence in Bulgaria. Gastroesophageal reflux disease Epidemiology Proton pump inhibitors Prevalence risk factors Gastroesophageal reflux disease...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2014) 32 (1-2): 152–155.
Published Online: 28 February 2014
... blockers. The introduction of proton pump inhibitors (PPIs), however, substantially improved medical therapy. Still, treatment failures are inevitable regardless of which of these two effective therapies is chosen. Some recent reports have presented conflicting results from trials comparing antireflux...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (5): 499–506.
Published Online: 16 November 2011
... adenocarcinoma Acid inhibition Proton pump inhibitors Antireflux surgery Barrett’s esophagus (BE) is an important premalignant condition in which the squamous epithelium of the distal esophagus is replaced by columnar epithelium-containing goblet cells [ 1 ]. BE is a complication of chronic...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (5): 469–475.
Published Online: 16 November 2011
...Z. Krznaric; D. Ljubas Kelecic; N. Rustemovic; D. Vranesic Bender; R. Ostojic; P. Markos; C. Scarpignato Despite the well-established benefits of currently approved delayed-release proton pump inhibitors (PPIs) in the treatment of acid-related diseases, the unmet needs are still present...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (5): 494–498.
Published Online: 16 November 2011
... procedures for only a small portion of patients unresponsive to ‘conventional’ therapy. Technological advancement has seen a great improvement in the field of endoscopic treatment in the form of various methods of hemostasis. However, pharmacological therapy with proton pump inhibitors still plays...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2009) 27 (1): 68–73.
Published Online: 08 May 2009
...Jochen Weigt; Arne Kandulski; Franziska Büsch; Peter Malfertheiner Background: Nocturnal acid breakthrough (NAB) is defined as gastric pH below 4 over 60 consecutive minutes at night-time in subjects who take proton pump inhibitors twice daily. The link between NAB and gastroesophageal reflux (GER...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2009) 27 (1): 58–61.
Published Online: 08 May 2009
...Jan Tack; Kathleen Blondeau The advent of pH impedance monitoring has allowed assessment of the role of weakly acidic reflux, in addition to the traditionally considered acid reflux, in the pathophysiology of gastroesophageal reflux disease. Typical reflux symptoms studied off proton pump inhibitor...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2009) 26 (4): 291–299.
Published Online: 30 January 2009
... on the elderly and the increasing use of non-steroidal anti-inflammatory drugs as precipitating bleeding episodes. Apart from initial critical care, endoscopy is the preferred first-line management of PUB. Early use of empirical high-dose proton pump inhibitor therapy prior, during and after endoscopy is cost...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (1997) 15 (1-2): 92–99.
Published Online: 04 November 2008
..., instructions or products referred to in the content or advertisements. Peptic ulcer Duodenal ulcer Gastric ulcer Long-term management Helicobacter pylori Non-steroidal anti-inflammatory drugs Proton pump inhibitors H 2 -receptor antagonists Digestive Diseases Original Paper Dig Dis 1997:15:92...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2008) 26 (3): 215–217.
Published Online: 06 May 2008
...Nimish Vakil Proton pump inhibitors are widely used in many upper gastrointestinal disorders. Dyspepsia is a common problem in primary care and endoscopy is neither feasible nor affordable in the majority of patients. Helicobacter pylori eradication has been shown to be effective...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2007) 25 (3): 175–178.
Published Online: 10 September 2007
...Andreas Leodolter; Roberto Penagini On-demand proton pump inhibitor (PPI) therapy is an attractive option for long-term management of gastroesophageal reflux disease (GERD). Controlled trials in non-erosive reflux disease (NERD) patients have shown sufficient symptom control in most patients...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2007) 25 (3): 172–174.
Published Online: 10 September 2007
... patients with a positive correlation between symptoms and reflux events, in whom heartburn can be controlled by proton pump inhibitor (PPI) therapy. According to the recent Rome III criteria, they are still in the realm of GERD. An additional group is called functional heartburn, because this typical...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2006) 24 (1-2): 11–46.
Published Online: 12 May 2006
... of patients with gastroesophageal symptoms who do not respond adequately to proton pump inhibitor (PPI) therapy, treatment of patients with nonvariceal upper gastrointestinal bleeding, prevention of stress-related mucosal bleeding, optimal treatment and prevention of NSAID-related gastrointestinal injury...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2004) 22 (2): 171–180.
Published Online: 23 September 2004
... and bile acids have been reported as potential insults involved in the pathogenesis of Barrett’s oesophagus. This is thought to be mediated by a range of molecules including cyclo-oxygenase-2, c-myc and mitogen-activated protein kinase signalling. Proton pump inhibitors not only suppress acid but also bile...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2001) 19 (3): 240–243.
Published Online: 12 December 2001
..., instructions or products referred to in the content or advertisements. Non-ulcer dyspepsia Proton pump inhibitors H. pylori Review Article Dig Dis 2001;19:240 243 Treatment Options for Functional Dyspepsia Nimish Vakil University of Wisconsin Medical School, Milwaukee, Wisc., USA Key Words Non...