... failure Liver function Portal hypertension There are no financial disclosures, grants from any organs, conflicts of interest, and/or acknowledgements for the authors to declare. Shaanxi social development fund (Fund No. 2020SF-067). Study concept and design: Yan Xu and Rui dong...

...: One hallmark of chronic liver disease in patients with portal hypertension is the formation of portal-systemic collaterals in which angiogenesis has a fundamental role. We studied patients with chronic liver disease undergoing liver transplantation to correlate levels of circulating angiogenic factors...

...Matthias Buechter; Paul Manka; Guido Gerken; Ali Canbay; Sandra Blomeyer; Axel Wetter; Jens Altenbernd; Alisan Kahraman; Jens M. Theysohn Background and Aims: Transjugular intrahepatic portosystemic shunt (TIPS) is the treatment of choice in decompensated portal hypertension. TIPS revision due...

...Frederik Nevens Background: Complications of advanced liver disease occur at the moment of clinical significant portal hypertension. Nitric oxide (NO) dysfunction and fibrosis play an important role in the pathophysiology of PH, but other mechanisms are also involved. Non-selective beta blockers...

... can be evaluated concurrently with portal haemodynamic changes allowing non-invasive assessment of portal hypertension and effects of interventions. A combination ultra-high field (7T) provides greater sensitivity with a potential to distinguish inflammation from fibrosis on imaging and determine...

... discusses how to translate our current understanding of ascites pathophysiology into new treatment methods for patients with fluid retention. [email protected] 3 5 2017 Cirrhosis Ascites Portal hypertension Sodium retention  Hypervolemic hyponatremia Hepatorenal syndrome...

... liver fibrosis. Hepatology 2012;55:1965-1975. 19. Fallowfield JA, Hayden AL, Snowdon VK, et al: Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo. Hepatology 2014;59:1492-1504. 20. Kobalava Z, Villevalde S, Kotovskaya Y, et al...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Angiogenesis Chronic liver diseases Cirrhosis Fibrogenesis Fibrosis Portal hypertension The set of morphologic...

...Jordi Gracia-Sancho; Raquel Maeso-Díaz; Jaime Bosch Portal hypertension is a common complication of chronic liver disease. Its relevance comes from the fact that it determines most complications leading to death or liver transplantation in patients with cirrhosis of the liver: bleeding from...

... stages and predictors should be recognized in order to correctly stratify the prognosis and individualize possible therapeutic options. Key Messages: In compensated cirrhosis the presence of clinically significant portal hypertension [CSPH = hepatic venous pressure gradient (HVPG) ≥10 mm Hg] constitutes...

... of concomitant/underlying metabolic conditions with statins or metformin may also have beneficial effects on portal hypertension, complications of liver cirrhosis and HCC prevention. The bile acid receptor FXR may be a promising novel therapeutic target for the treatment of NAFLD/NASH, fibrosis and portal...

...Juan G. Abraldes; Puneeta Tandon Variceal bleeding is the most serious complication of portal hypertension. All cirrhotic patients should be screened endoscopically for varices which are present in about 30% of compensated and 60% of decompensated patients at diagnosis. In patients without varices...

...Lucía C. Fry; Helmut Neumann; Carolina Olano; Peter Malfertheiner; Klaus Mönkemüller Background: Bleeding gastric varices (BGV) are a severe complication of portal hypertension. Although the obliteration of gastric varices using cyanoacrylate has been shown effective to eradicate gastric varices...

...Hector H. Trevino; Charles E. Brady III; Steven Schenker Portal hypertensive gastropathy (PHG) is part of a complex syndrome which occurs as a complication of chronic liver disease and portal hypertension (PHTN). At endoscopy, the gastric mucosa shows that mosaic-like pattern and red marks, which...

...Hussein M. El-Newihi; James L. Achord Bleeding from esophageal varices is the most catastrophic complication of portal hypertension. The associated high morbidity and mortality have necessitated the development of safe and efficacious therapeutic modalities. In recent years, endoscopic band...

...Richard J. Gusberg Despite progress in our understanding and management of patients with portal hypertension, the long-term control of variceal bleeding remains a significant challenge. With further clarification of the underlying pathophysiology and technological advances that have facilitated...

.... Esophageal varices Portal hypertension Cirrhosis Portosytemic shunt Esophageal transection Vasopressin Somatostatin Dig Dis 1992:1 suppl l):46-55 Jonathan j . Lewis irvin m . Modim Gastrointestinal Surgical Pathobiology Research Unit. Department of Surgery, Yale University School of Medicine. New...

...-term patency of interventional shunts, and justified their clinical application. The rationales for this new approach to the treatment of portal hypertension are its relative safety, even in Child C patients, and the disabilities such as rebleeding or aggravation of hepatic encephalopathy of other...

... the bleeding and follow-up data for at least 6 months were available. 90.5% of these patients had nonalcoholic etiology for their portal hypertension. 60.8% of patients developed recurrent varices and 11.1% had recurrent bleeding from esophageal varices. The bleeding risk index, calculated as the number...

.... Sclerotherapy Portosystemic shunt Portal hypertension Dig Dis 1992;10(suppl 1):38 45 Fuad Hasan Barry A. Levine Department oflntcrnal Medicine and Department of Surgery, University of Texas Health Science Center at San Antonio, Tex., USA The Role of Endoscopic Sclerotherapy in the Management of Esophageal...