.... Eosinophilic esophagitis Achalasia Esophagus Eosinophilia Pathogenesis Management Eosinophilic esophagitis (EoE) is nowadays considered a chronic allergic-immune condition of the esophagus that was not recognized as a unique clinicopathological entity up until 1993 [1]. Since then, its frequency...

...Ansgar W. Lohse; Johannes Herkel; Christina Weiler-Normann The pathogenesis of autoimmune hepatitis is still poorly understood and therefore, the therapy administered to treat this condition is broadly targeted immunosuppression. However, the aim of therapy in the future should be more specific...

... and enhances their responsiveness to eotaxin-3 and prolongs also their cellular survival. Eosinophils, T-cells and mast cells are elevated in esophageal mucosal biopsies with T-cells being polarized toward a Th2 immunity [ 22 ]. A recent publication highlighted a role for IgG4 in EoE pathogenesis [ 23...

... because bile duct disease continues to progress despite treatment in approximately 50% of patients. Ursodeoxycholic acid is usually added to conventional treatment regimen in ASC, but whether this actually helps arrest the progression of bile duct disease remains to be established. The pathogenesis...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2014 IBD Environmental factors Pathogenesis Induction of flares...

... with accompanying release of inflammatory cytokines (‘the senescent secretome') which contributes to the process of interface hepatitis which is a feature of high-risk and treatment-unresponsive disease. This model for pathogenesis of PBC has implications for potential therapy approaches in targeting both...

... in their pathogenesis. Thus, investigating differences and similarities between the diseases might be a worthwhile endeavor. Both EoE and asthma are chronic immune-mediated conditions characterized by inflammatory changes in the mucosa and submucosa with a characteristic and diagnostic infiltration of eosinophils...

... involving a complex polygenic etiology, much progress has been made towards identifying the molecular pathways contributing to the disease pathogenesis and the genetic variants associated with disease susceptibility using a variety of approaches (genome-wide and candidate gene) as well as study designs...

...Martina Böttner; Thilo Wedel The pathogenesis of diverticular disease is still poorly understood and considered to be multifactorial. Whereas classical pathogenetic concepts have focused on risk factors including increasing age, low-fiber diet and connective tissue disorders, novel concepts take...

... disease Pathology Pathogenesis Diverticula Diverticular disease (DD) is an age-related common anomaly that is seen mostly in the Western world linked by Painter and Burkitt’s group [ 1,2 ] to diet and dietary habits [ 3 ,][ 4 ]. The hypothesis proposed initially by Painter and Burkitt is both...

...Philippe Marteau The pathogenesis of inflammatory bowel disease (IBD) involves an interaction between host susceptibility (which is partly genetically determined), mucosal immunity and the intestinal milieu. Micro-organisms have physiological effects on mucosal structure, epithelial turnover...

...Paul Pavli; Peter R. Gibson Clues from patient and experimental animal studies suggest that events occurring early in the pathogenesis of Crohn’s disease are related to an inability of the immune system to eradicate one or a number of luminal antigens resulting in persistent T cell and macrophage...

... therapeutic approaches. Ulcerative colitis Inflammatory bowel disease Pathogenesis Etiology Epithelium Inflammation Immune mechanisms © 1992 S. Karger AG, Basel 1992 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other...

... Pathogenesis Therapy Dig Dis 1994;12:210-222 James M. Scheiman Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Mich., USA NSAID-Induced Peptic Ulcer Disease: A Critical Review of Pathogenesis and Management Key Words Peptic ulcer disease Nonsteroidal anti...

... concerning the pathogenesis and definition of NAFLD is reviewed Results: The reasons why NAFLD should be renamed are: (a) clinically meaningful hepatic steatosis could be present at less than 5% triglyceride hepatic content; (b) steatosis is usually no longer observed in the most advanced forms of NAFLD...

.... pylori infection Pathogenesis Original Paper Dig Dis 2001;19:170 173 H. pylori Infection and Visceral Hypersensitivity in Patients with Irritable Bowel Syndrome C. Gerardsa A. Leodoltera B. Glasbrennerb P. Malfertheinera aDepartment of Gastroenterology, Hepatology and Infectiology, Otto von Guericke...

... to in the content or advertisements. Atherosclerosis Cancer Diagnosis Epidemiology Fatty liver Nonalcoholic steatohepatitis Metabolic syndrome Natural history Pathogenesis Treatment Review Article Dig Dis 1999;17:80 89 Fatty Liver and Nonalcoholic Steatohepatitis Where Do We Stand and Where Are We...