...Ja Eun Koo; Hye-Sook Chang; Hye Won Park; Sungwon Park; Inyoung Bae; Ji Young Lee; Jaewon Choe Introduction: Abdominal obesity increases the risk of gastroesophageal reflux disease (GERD). This study aimed to determine the association between GERD and abdominal fat area quantified by computed...

... as a consequence of metabolic perturbations associated with obesity, type 2 diabetes, dyslipidemia, and insulin resistance. People with NAFLD may develop metabolic and cardiovascular complications and/or liver-related complications, especially fibrosis and hepatocellular carcinoma, associated with high morbidity...

... < −1.455 versus ≥−1.455 (33.74 vs. 27.83), though no differences were found by obesity or steatosis severity. The majority of males (85.7%) and females (60.7%) had normal to minimally elevated ALT (1–1.5 × 95% ULN). Individual patient-level data analysis ( N = 7,668) demonstrated similar results...

... steatohepatitis (NASH). In this study, we analyzed if an adjustment of the upper limit of normal (ULN) for serum liver enzymes can improve their diagnostic accuracy. Methods: Data from 363 morbidly obese patients (42.5 ± 10.3 years old; mean BMI: 52 ± 8.5 kg/m 2 ), who underwent bariatric surgery...

...Marziye Farsimadan; Fatemah Sadeghpour Heravi; Alireza Emamvirdizadeh; Samaneh Moradi; Hamidreza Iranpour; Ehsan Tabasi; Mohammad Reza Eskandarion; Reza Azizian; Mohsen Tabasi Introduction: Obesity is a well-known risk factor for a variety of gastrointestinal disorders (GID). Helicobacter pylori...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Fatty liver Epidemiology Mortality Diabetes Metabolic syndrome Obesity Nonalcoholic fatty liver disease (NAFLD...

...Benedikt A. Aulinger; Thuan To Viet; Elisa Waldmann; Klaus G. Parhofer Objective: Although obesity is associated with metabolic changes, not all obese patients are characterized by the metabolic syndrome (MS). The goal of this study was to determine the prevalence of the MS, its characteristics...

... abdominal surgeries. Bleeding is one of the most common complications in surgery for obesity that has the risk of being catastrophic. Methods: The study includes 8,544 cases that underwent bariatric surgery from January 2013 to March 2016 retrospectively, in 4 private institutions. Multiple demographic data...

...Davor Štimac; Sanja Klobučar Majanović; Andrej Belančić Background: Conventional approaches in the management of obesity offer only a limited potential for sustained weight loss. Moreover, bariatric surgery, although momentarily being the most effective weight-loss treatment, has some serious...

...Petr Dite; Martin Blaho; Martina Bojkova; Petr Jabandziev; Lumir Kunovsky Metabolic syndrome and its components such as obesity, hypertriglyceridemia, type-2 diabetes mellitus (DM-T2), and arterial hypertension are unequivocally serious problems for every society. This is especially true...

...C. Daniel De Magalhaes Filho; Michael Downes; Ronald M. Evans Obesity and its associated diseases, including type 2 diabetes, have reached epidemic levels worldwide. However, available treatment options are limited and ineffective in managing the disease. There is therefore an urgent need...

...Ashley Patton; Farooq H. Khan; Rohit Kohli Background: Bariatric surgery is a popular and effective therapeutic intervention for obesity, which is an abnormal health condition that is prevalent worldwide. Metabolic improvements that precede weight loss after bariatric surgery may be mediated...

... is correlated with metabolic diseases, notably obesity and non-alcoholic fatty acid disease (NAFLD). Recent studies revealed that bacterial metabolism of BA can modulate FXR signaling in the intestine by altering the composition and concentrations of FXR agonist and antagonist. FXR agonist enhances while FXR...

... with high calorie (either high-fat or high-carbohydrate) diets. The gut microbiota may also be involved via obesity, IR and hepatic inflammation generated by gut-derived toxic factors. Finally, several data also support a primary role of genetic factors. A few gene polymorphisms have also been associated...

... and hepatocellular carcinoma worldwide. NAFLD is considered as the hepatic manifestation of the metabolic syndrome. With the pandemic rise of obesity, the incidence of NAFLD is also further increasing, and considering the life style in modern societies, there is a significant overlap of (risk factors causing) NAFLD...

...Eiji Hara During the past several decades, the percentage of excess bodyweight and obese adults and children has increased dramatically, and is becoming one of the most serious public health problems worldwide. Extensive epidemiological studies have revealed that there is a strong link between...

...Rohit Kohli; Andriy Myronovych; Brandon K. Tan; Rosa-Maria Salazar-Gonzalez; Lili Miles; Wujuan Zhang; Melissa Oehrle; Darleen A. Sandoval; Karen K. Ryan; Randy J. Seeley; Kenneth D.R. Setchell Bariatric surgery is the most effective and durable treatment option for obesity today. More importantly...

... global obesity and gastroesophageal reflux disease rates may be contributing to the rise in FD. Socioeconomic and cultural demographic changes such as changing dietary habits and rapid urbanization, particularly in the developing countries, are likely to be influencing the course of FD and the way...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2012 Obesity Microbiota <italic>Firmicutes</italic> <italic>Bacteroidetes</italic...

...Maja Baretić Obesity has more than doubled since 1980 all over the world, and in the European perspective it does not seem to be better. Obesity-related diseases like diabetes, hypertension, coronary heart disease, stroke and hyperlipidemia are the main cause of mortality and morbidity in developed...