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Keywords: Nuclear receptors
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Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (3): 282–287.
Published Online: 01 March 2017
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Metabolic syndrome . Obesity NASH Nuclear receptors Farnesoid X receptor Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (3): 261–266.
Published Online: 01 March 2017
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Enterohepatic circulation Intestine Liver Transporters Nuclear receptors National Institutes of Health (NIH) 10.13039/100000002...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (3): 415–419.
Published Online: 27 May 2015
...Vincent Zimmer; Roman Liebe; Frank Lammert This snapshot reviews the current state of knowledge on genetic variants of nuclear receptors (NRs) involved in regulating various aspects of liver metabolism. Interindividual differences in responses to diet and other ‘in-' and environmental stressors can...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (3): 357–366.
Published Online: 27 May 2015
...Ester Gonzalez-Sanchez; Delphine Firrincieli; Chantal Housset; Nicolas Chignard Background: Nuclear receptors (NRs) form a family of 48 members. NRs control hepatic processes such as bile acid homeostasis, lipid metabolism and mechanisms involved in fibrosis and inflammation. Due to their central...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (Suppl. 1): 39–47.
Published Online: 11 October 2012
... prognosis. This article is a summary of an overview given at the 5th Falk Gastro Conference in Munich 2012 and reviews the challenges associated with diagnosis, surveillance and therapy of PSC. Cholestasis Cholangiocellular carcinoma Bile acids Nuclear receptors 11 10 2012 © 2012 S...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (1): 52–57.
Published Online: 17 June 2011
.... These functions are all controlled by nuclear receptors. The biliary tree conveys bile, a complex fluid containing toxics such as endotoxins, from the liver to the duodenum. Active protection against endotoxins can be elicited by the vitamin D receptor or the farnesoid X receptor (FXR), thus avoiding constant...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (1): 37–44.
Published Online: 17 June 2011
... homeostasis, lipid metabolism and energy expenditure – processes relevant in the context of the metabolic syndrome. In addition to the function of the nuclear receptor FXRα in regulating local effects of BAs in the organs of the enterohepatic axis, increasing evidence points to a crucial role of the G-protein...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (1): 98–102.
Published Online: 17 June 2011
...Michael Trauner; Anna Baghdasaryan; Thierry Claudel; Peter Fickert; Emina Halilbasic; Tarek Moustafa; Gernot Zollner Bile acids (BAs) are able to activate a range of dedicated nuclear receptors (NRs) which play a key role in the transcriptional control of critical steps of a wide range of hepatic...