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1-5 of 5
Keywords: Mucus
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Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestive Diseases
Dig Dis (2017) 35 (1-2): 21–24.
Published Online: 01 February 2017
...Eduard F. Stange In Crohn's disease, the mucus layer appears to be defective in terms of low defensin levels and lack of antibacterial activity. These deficiencies actually explain the Montreal phenotypes and the stable localization of disease in the terminal ileum with low α-defensins from Paneth...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestive Diseases
Dig Dis (2013) 31 (3-4): 388–390.
Published Online: 14 November 2013
...Wolfgang Stremmel; Annika Gauss Lecithin [phosphatidylcholine (PC)] was shown to account for more than 70% of total phospholipids within the intestinal mucus layer. It is arranged in lamellar membranes (surfactant-like particles) and establishes a hydrophobic barrier preventing invasion...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestive Diseases
Dig Dis (2013) 31 (3-4): 305–309.
Published Online: 14 November 2013
...Malin E.V. Johansson; Gunnar C. Hansson The discovery of an inner mucus layer normally impervious to bacteria has changed our way of understanding the interaction between commensal bacteria and the host epithelial cells. This inner colon mucus layer is rapidly renewed and converted into the outer...
Journal Articles
Subject Area:
Gastroenterology
Wolfgang Stremmel, Robert Ehehalt, Sabine Staffer, Sabine Stoffels, Andrea Mohr, Max Karner, Annika Braun
Journal:
Digestive Diseases
Dig Dis (2013) 30 (Suppl. 3): 85–91.
Published Online: 03 January 2013
...Wolfgang Stremmel; Robert Ehehalt; Sabine Staffer; Sabine Stoffels; Andrea Mohr; Max Karner; Annika Braun The colonic mucus serves a first barrier towards invasion of commensal bacteria in stools to prevent inflammation. One essential component of intestinal mucus is phosphatidylcholine (PC) which...
Journal Articles
Subject Area:
Gastroenterology
Journal:
Digestive Diseases
Dig Dis (2010) 28 (3): 490–496.
Published Online: 30 September 2010
...Wolfgang Stremmel; Anja Hanemann; Robert Ehehalt; Max Karner; Annika Braun Colonic mucus protects against attacks from bacteria in stool. One component of mucus is phosphatidylcholine (PC) which is thought to be arranged as continuous lamellar layer in the apical mucus and to be responsible...