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Journal: Digestive Diseases
Dig Dis (2011) 28 (6): 745–750.
Published Online: 27 April 2011
... of ALD. Metallothionein (MT) is a major protein responsible for cellular zinc homeostasis. MT-transgenic (MT-TG) mice with hepatic overexpression of MT and elevation of zinc level were resistant to ethanol-induced liver injury. MT-knockout (MT-KO) mice with a reduction of hepatic zinc were more...