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Keywords: Lynch syndrome
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Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (1): 58–67.
Published Online: 17 December 2014
... for cancer prevention. In familial adenomatous polyposis (FAP) and Lynch syndrome, most of the underlying germline mutations can be detected by DNA sequencing, and medical counselling of affected individuals involves both surveillance tests and chemopreventive measures. However, as the mechanisms leading...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (Suppl. 2): 39–47.
Published Online: 23 November 2012
...John Burn; John Mathers; D. Tim Bishop Hereditary cancer due to pathological mutations in the mismatch repair gene family is now known as Lynch syndrome and affects at least 1 in 1,000 people, resulting in a 30–50% cancer risk most often involving the colorectum and endometrium. Annual or biennial...