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Keywords: Insulin resistance
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Journal Articles
Journal Articles
Dig Dis (2016) 34 (Suppl. 1): 11–18.
Published Online: 22 August 2016
..., cardiac diseases and chronic kidney disease, to name but a few. Of each of these extrahepatic diseases, the evidence to date suggests that NAFLD is a strong risk factor for T2DM. When NAFLD occurs in combination with obesity and insulin resistance (as it frequently does), there is a marked increase...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (3): 426–432.
Published Online: 27 May 2015
...Arun J. Sanyal Nonalcoholic fatty liver disease is a common cause of liver related morbidity and mortality. It is closely linked to underlying insulin resistance. It has recently been shown that bile acids modulate insulin signaling and can improve insulin resistance in cell based and animal...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (2): 243–248.
Published Online: 05 July 2011
...Massimo Pinzani Non-alcoholic fatty liver disease (NAFLD) is likely the most common cause of liver disease in adults as well as in children and adolescents. Its occurrence is closely associated with obesity and insulin resistance. NAFLD may lead to non-alcoholic steatohepatitis (NASH) with possible...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (1): 117–118.
Published Online: 17 June 2011
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Insulin resistance Glucose tolerance Bariatric surgery The prevalence...
Journal Articles
Dig Dis (2010) 28 (1): 210–213.
Published Online: 07 May 2010
...Gianluca Perseghin Background/Aims: Fatty liver is the hepatic component of the metabolic syndrome. Insulin resistance, the pathogenic driver of the metabolic syndrome, refers to a constellation of features such as overweight/obesity, glucose intolerance, dyslipidemia and hypertension, all of which...
Journal Articles
Journal Articles
Dig Dis (2010) 28 (1): 169–178.
Published Online: 07 May 2010
... of triglycerides in the form of very-low-density lipoproteins). New aspects concerning mechanisms potentially leading to a ‘dissociation’ of fatty liver and insulin resistance are also discussed. Understanding the pathogenesis of fatty liver and its complications, including the identification of new factors...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2010) 28 (1): 247–254.
Published Online: 07 May 2010
... of liver fibrosis, which can progress to cirrhosis. Hepatocellular carcinoma can develop in patients with NASH, even in the absence of cirrhosis. The majority of patients with primary NASH exhibit risk factors that define the metabolic syndrome including insulin resistance and visceral obesity. However...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2010) 28 (1): 236–246.
Published Online: 07 May 2010
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. PTEN Obesity Liver Insulin resistance Steatosis Fibrosis Hepatocellular carcinoma Liver and Metabolic Syndrome Dig Dis 2010;28:236 246 DOI...
Journal Articles
Dig Dis (2010) 28 (1): 179–185.
Published Online: 07 May 2010
...Herbert Tilg Non-alcoholic fatty liver disease (NAFLD) is commonly associated with obesity and diabetes, and is characterized by insulin resistance (IR). Cytokines and adipocytokines (i.e. mediators mainly derived from adipose tissue) play a major role in the orchestration of inflammatory processes...
Journal Articles
Dig Dis (2010) 28 (1): 280–284.
Published Online: 07 May 2010
...Sabine Mihm Infection with hepatitis C virus (HCV) primarily causes chronic liver disease with characteristic histopathologic features, including hepatic steatosis. Moreover, chronic hepatitis C is also closely related to insulin resistance (IR) and an increased risk of type 2 diabetes mellitus (DM...
Journal Articles
Dig Dis (2010) 28 (1): 186–191.
Published Online: 07 May 2010
... globally and is associated with insulin resistance, steatosis and a low-grade systemic inflammatory state. These metabolic factors have a synergistic role in the natural history and treatment outcomes related to chronic liver disease. This is characterized best in chronic hepatitis C where steatosis...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2005) 23 (1): 72–82.
Published Online: 19 May 2005
...Paola Loria; Amedeo Lonardo; Nicola Carulli Background: None of the synonyms of nonalcoholic fatty liver disease (NAFLD) include clinical correlates nor do they mention insulin resistance, a recognized determinant of the etiopathogenesis and natural history of NAFLD. Method: The literature...