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Keywords: Inflammation
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2020) 38 (5): 398–407.
Published Online: 20 March 2020
...Stefan Reischl; Jasmin Troger; Moritz Jesinghaus; Atsuko Kasajima; Dirk Felix Wilhelm; Helmut Friess; Philipp-Alexander Neumann Introduction: Crohn’s disease (CD) is characterized by relapsing intestinal inflammation. The anti-inflammatory protein annexin A1 (ANXA1) has been linked to inflammatory...
Journal Articles
Dig Dis (2019) 37 (6): 509–517.
Published Online: 06 June 2019
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hepatic encephalopathy Cirrhosis Inflammation Ammonia Cytokine profile Hepatic encephalopathy (HE) is a sign of end-stage liver disease...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2019) 37 (6): 444–450.
Published Online: 30 April 2019
.... Inflammatory bowel disease Inflammation Crohn’s disease Ulcerative colitis Crohn’s disease (CD) and ulcerative colitis (UC) are chronic diseases characterized by gastrointestinal tract inflammation, with a severe impact on the quality of life of patients. Tumor necrosis factor alpha (TNFα) plays...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2018) 35 (Suppl. 1): 36–42.
Published Online: 08 February 2018
... to in the content or advertisements. Herbs Herbal drugs Bitter drugs Aromatic drugs Spasmolysis Inflammation Combination medicines Judging by the historic medicinal literature, functional gastrointestinal diseases (FGID) have always been an issue in the history of mankind, and herbal...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2018) 35 (Suppl. 1): 5–13.
Published Online: 08 February 2018
... mechanisms for gut-brain dysfunction have been identified, with systemic minimal inflammation as a causal factor in at least some subjects. Other mechanisms that play a role in FGID include chronic infections, intestinal microbiota, low-grade mucosal inflammation including the increase of eosinophils...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (4): 390–396.
Published Online: 03 May 2017
...-based approaches is yet to be experienced. Notwithstanding this, the etiological background of hepatobiliary cancer - overlapping in almost every known causative or associated factor with inflammation - provides a strong clue that these approaches may have an impact on this group of diseases...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (3): 232–234.
Published Online: 01 March 2017
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bile acid Cholestasis Inflammation Cytokines Abcb4 –/– In the last decade, a number of studies have suggested that bile acids may injure liver cells...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2016) 34 (5): 589–596.
Published Online: 22 June 2016
... fibrosis. Therefore, new strategies for anti-fibrotic therapy are required. Various kinds of hepatocyte damage result in inflammation, which leads to the activation of hepatic stellate cells (HSCs), which are the major source of myofibroblasts in the liver. Myofibroblasts proliferate in response to various...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2016) 34 (1-2): 64–71.
Published Online: 16 March 2016
... like F. prausnitzii is associated with better clinical outcomes, especially in adult IBD patients. However, despite these advances in our understanding of the mechanistic implications of dysbiosis, whether this dysbiosis is a cause or consequence of inflammation in IBD patients remains unresolved. We...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2016) 34 (1-2): 78–83.
Published Online: 16 March 2016
... of IBD are on the rise within the last few years, especially in non-western countries. One of those factors is believed to be hypoxia. The role of hypoxia as a modifying or even causative factor in the genesis and maintenance of inflammation has been increasingly elucidated in recent years. Hypoxia...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (3): 319–326.
Published Online: 27 May 2015
... inflammation and defective adaptation of biliary composition (bicarbonate and chloride). Most importantly, TGR5-KO mice had a more hydrophobic BA pool, with more secondary BA than WT animals, suggesting that TGR5-KO bile may be harmful for the liver, mainly in situations of BA overload. As GB is both...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2014) 32 (5): 564–569.
Published Online: 14 July 2014
...Sumera Rizvi; Gregory J. Gores It has become increasingly apparent of late that inflammation plays an integral role in a spectrum of malignancies including cholangiocarcinoma (CCA). Primary sclerosing cholangitis with chronic inflammation is the most common risk factor for CCA in the Western world...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2014) 32 (1-2): 11–14.
Published Online: 28 February 2014
... the pathophysiology of the underlying inflammation. Results and Conclusions: Evidence has accumulated that EoE represents a T-helper (Th) 2-type inflammatory disease, in which allergens play a role in triggering the disease. The majority of the patients suffer from concurrent allergic rhinitis, asthma, and eczema...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (Suppl. 2): 9–15.
Published Online: 23 November 2012
...Hirokazu Okayama; Aaron J. Schetter; Curtis C. Harris There is a strong connection between inflammation, altered microRNA (miRNA) expression and colon cancer. Longstanding inflammatory bowel diseases-related colitis leads to increased risk for the development of colorectal cancer (CRC), while...
Journal Articles
Dig Dis (2012) 30 (5): 508–513.
Published Online: 24 October 2012
... homeostasis (i.e. health) and disease, especially in obesity-related disorders such as non-alcoholic fatty liver diseases (NAFLD) and their complications, including hepatocellular carcinoma (HCC). Lack of adiponectin as observed in NAFLD drives steatosis and inflammation in the liver, and evidence...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (5): 500–507.
Published Online: 24 October 2012
.... However, current systemic molecular therapies against HCC are mainly focusing on tyrosine kinases involved in angiogenic and oncogenic signaling pathways, whereas the knowledge on the unique association between inflammation and carcinogenesis in the liver has not yet translated into preventive...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (5): 492–499.
Published Online: 24 October 2012
...Athena Chalaris; Dirk Schmidt-Arras; Kosuke Yamamoto; Stefan Rose-John Interleukin-6 (IL-6) is a cytokine largely induced during infection, inflammation, and cancer. In the liver, IL-6 induces the synthesis of acute-phase proteins, which are believed to support the response of the body during...