... Immunomodulation Celiac disease (CeD) is a paradigm of autoimmune disorders characterized by an inappropriate immune response to dietary gluten [ 1 ]. Gluten is a complex protein found in wheat, barley, and rye, and its ingestion is a common part of daily diets worldwide [ 2 ]. In genetically susceptible...

... against allergic and other immunological disorders. We then focus on the mechanistic basis of microbial immunomodulation, which is presented using several well-understood paradigmatic examples, that is, helminths, Helicobacter pylori , Bifidobacteria and Lactobacilli. In a final chapter, we highlight past...

... disease Epitope masking Gliadin Immunomodulation Regulatory T cells Fig. 2 Schematic view of the exogenous pathway involved in peripheral tolerance. This mechanism is exploited by the different prophylactic approaches under investigation for CD. Fig. 2. Schematic view of the exogenous...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2014 Mesenchymal stromal cells Crohnߣs disease Immunomodulation...

... decades have seen a dramatic shift in therapeutic approach with the increasingly common use of early thiopurine immunomodulation. These maintenance medications were initially introduced primarily as corticosteroid-sparing agents capable of minimizing recurrent flares of inflammatory disease and have...