...]. The inhibition by cimeti­ dine was found to be noncompetitive by Seitz et al. [67] whereas Hernández-Muñoz et al. Effects of H2-Receptor Antagonists [33] found it to be competitive at low etha­ nol concentrations and noncompetitive only The effects of some H2-receptor antago­ when low Km activities were...

... gastrointestinal injury. * p = 0.002; ** p < 0.0001 vs. placebo [from 6J. Other prostaglandin analogues that have been reported to heal NSAID-associated gas­ tric damage include enprostil 70-105 pg/day [11] rioprostil 400-450 pg/day [12], and arbaprostil 10-50 pg/day [ 13]. Histamine H2-Receptor Antagonists...

... on half-life and can easily be prolonged by ap- 30 Dig Dis 2006;24:11 46 Scarpignato/Pelosini/Di Mario Fig. 15. Chemical structure of the novel H2-receptor antagonists ebrotidine and lafutidine. Besides S- and R-isomers, cis- and trans-isomers of lafutidine have also been isolated. Table 5. P-CABs...