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Keywords: Fibrosis
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Journal Articles
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (4): 304–309.
Published Online: 03 May 2017
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alcohol Cirrhosis Fibrosis Non-alcoholic fatty liver Viral hepatitis The profile of liver disease has greatly increased over recent years. The recognition...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (4): 314–322.
Published Online: 03 May 2017
...Stephen J. Bawden; R.A. Scott; Guruprasad P. Aithal Background: In the past decades, a number of non-invasive methods have emerged for detecting and estimating liver fibrosis; these include both serum-based panels and imaging-based technology. Some of these methods are now being incorporated...
Journal Articles
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2017) 35 (1-2): 32–37.
Published Online: 01 February 2017
...Peter D.R. Higgins Background: Distinguishing fibrosis from inflammation in an intestinal stricture in Crohn's disease is quite difficult. The absence of signs of inflammation on CT or MRI does not prove the absence of inflammation, as most strictures have a mix of fibrosis and inflammation...
Journal Articles
Dig Dis (2016) 34 (Suppl. 1): 19–26.
Published Online: 22 August 2016
... or 4 fibrosis, including the NAFLD fibrosis score, fibrosis-4 and the enhanced liver fibrosis test. Of the imaging techniques, elastography has received the most attention and is being used in routine clinical practice. US acoustic radiation force impulse imaging, and MR-based elastography have...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2016) 34 (4): 374–381.
Published Online: 11 May 2016
... stress are also emerging. A variable degree of regression of fibrosis and even cirrhosis has been described, in experimental models, after suspension of the liver disease causative agent. As some individual features influence the rate of fibrosis progression, genetic and epigenetic factors are likely...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (Suppl. 2): 115–117.
Published Online: 07 December 2015
...Raoul Poupon PBC (formerly known as primary biliary cirrhosis and now named primary biliary cholangitis) is a disease with a wide range of severity and variable rate of progression. The diagnosis of advanced liver fibrosis/cirrhosis portends an increased risk of liver-related morbidity...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (4): 492–497.
Published Online: 06 July 2015
... of the wound-healing reaction. The process may result in clinically evident liver cirrhosis and hepatic failure. Although cirrhosis is the common result of progressive fibrogenesis, there are distinct patterns of fibrotic development related to the underlying disorders causing the fibrosis. These different...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2015) 33 (3): 426–432.
Published Online: 27 May 2015
... score Fibrosis LDL-cholesterol HDL-cholesterol Nonalcoholic fatty liver disease (NAFLD) has emerged as the leading cause of chronic liver disease in the Western world and is rapidly increasing in prevalence in other regions as well [ 1 ]. The clinical-histological spectrum of NAFLD includes...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2014) 32 (5): 494–501.
Published Online: 14 July 2014
... in hepatocyte proliferation and angiogenesis in improving liver injury [ 54,55 ]. Exogenously administered IL-10 has been shown to reduce fibrosis in an animal model and serum IL-10 levels have been reported to increase following cell infusion [ 56,57 ]. Alterations in the infiltration of endogenous cells...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2014) 32 (1-2): 15–21.
Published Online: 28 February 2014
... tissue, and includes basal zone hyperplasia, epithelial mesenchymal transition, fibrosis, angiogenesis, and smooth muscle hypertrophy/hyperplasia. Previously, research on the clinical impacts of tissue remodeling has been limited by a paucity of human tissue. However, in EoE, recurrent biopsies...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2013) 31 (2): 186–193.
Published Online: 06 September 2013
... of intestinal fibrosis. 6 9 2013 Inflammatory bowel disease Fibrosis Fistula Disease course The bulk of human-associated microbes are found in the gut, where they influence health and disease depending on whether the normal symbiotic balance between microbial and human cells...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (6): 547–553.
Published Online: 13 December 2012
... and female patients are listed in table 1 . The liver fibrosis stage (F-stage) of the background liver of the HCC patients was determined using the METAVIR scoring system [ 10 ]. Informed consent was obtained from patients, and the study was approved by the institutional review boards of the institutions...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2012) 30 (Suppl. 1): 61–68.
Published Online: 11 October 2012
...(s) of NAFLD and semiquantitative methods of assessment are reviewed. The unique patterns of injury and fibrosis that characterize this disease are emphasized, and reasons why histologic scoring and diagnosis are considered as interrelated but separate exercises given. In addition, pros and cons...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 29 (4): 371–376.
Published Online: 30 August 2011
...Fabio Marra; Nadia Navari; Elisa Vivoli; Sara Galastri; Angela Provenzano Hepatic fibrosis is an integrated process triggered by chronic liver damage, leading to the accumulation of extracellular matrix. In patients with chronic liver disease, this process is favored by the presence of obesity...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2011) 28 (6): 729–736.
Published Online: 27 April 2011
.... Alcoholic liver disease Animal models Steatosis Inflammation Fibrosis It is well known that alcoholic liver disease (ALD) results from the dose- and time-dependent consumption of alcohol [ 1 ]. Progression of ALD is well characterized and is actually a spectrum of liver diseases which ranges...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2010) 28 (1): 236–246.
Published Online: 07 May 2010
..., particularly in the context of non-alcoholic fatty liver disease (NAFLD), support a critical role for PTEN in hepatic insulin sensitivity and the development of steatosis, steatohepatitis and fibrosis. PTEN mutations/deletion or low PTEN expression are also associated with diverse liver malignancies...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2006) 23 (3-4): 255–263.
Published Online: 27 February 2006
... of alcoholic liver disease, especially on steatosis, alcoholic hepatitis and fibrosis. Methods: The various forms of alcoholic liver disease are described, and knowledge about the clinical and pathophysiological features of different stages of alcoholic liver disease are summarized. Results: Clinical studies...