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Keywords: Ethanol
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Journal Articles
Subject Area:
Gastroenterology
Dig Dis (1994) 12 (4): 232–241.
Published Online: 04 November 2008
..., and in gastrointestinal lesions following hemorrhagic shock, ischemia-reperfusion, and ingestion of nonsteroidal anti-inflammatory drugs, or ethanol. Leukocyte-endothelial cell interactions also appear to be a target for the action of various drugs proven to be useful in the treatment of gastrointestinal inflammatory...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2006) 23 (3-4): 181–194.
Published Online: 27 February 2006
... to the fact that controlled experimental studies of ethanol-induced diseases in humans are unethical. Animal models have already been successfully applied to disclose and analyze molecular mechanisms in alcohol-induced diseases, partially by using knockout technology. Because of a lack of transferability...
Journal Articles
Subject Area:
Gastroenterology
Dig Dis (2006) 23 (3-4): 264–274.
Published Online: 27 February 2006
... hypoxia and the formation of cell-toxic and profibrogenic ethanol metabolites (e.g. acetaldehyde or lipid oxidation products). These factors, based on a complex network of cytokine actions, together result in increased hepatocellular damage and activation of hepatic stellate cells, the key cell type...