... , Straif K , International Agency for Research on Cancer Handbook Working Group . The IARC perspective on colorectal cancer screening . N Engl J Med . 2018 ; 378 ( 18 ): 1734 – 40 . 3. Paris Workshop P . The Paris endoscopic classification of superficial neoplastic lesions: esophagus...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Colorectal cancer Gastrointestinal surgery Oncology Outcomes Thoracic imaging Lung metastases (LMs) of colorectal cancer (CRC) are diagnosed synchronously in up to 17...

...Chiara Pierantoni; Lorenzo Cosentino; Luigi Ricciardiello Background: Colorectal cancer is known as one of the “big killers” in oncology given its burden in terms on morbidity and mortality. Since the second half of the last century, similarly to what happened for other solid tumors, a large series...

...). In IBD clinical trials, endoscopy is used to assess mucosal disease activity before and after treatment but also provides an opportunity to surveil for colorectal neoplasia during follow-up. Summary: Best practices for colorectal cancer identification in IBD clinical trials require engagement...

... clustered in microsatellite repeats. Thus, microsatellite instability (MSI) is the epiphenomenon of dMMR. In colorectal cancer (CRC), MMR/MSI status is a biomarker with prognostic and predictive value of resistance to 5-fluorouracil and response to immune checkpoint inhibitor therapy. Summary...

...; on behalf of Italian Society of Gastroenterology (AIGO), Italian Society of Digestive Endoscopy (SIED) and Italian Society of Gastroenterology and Digestive Endoscopy (SIGE) Background: Hereditary colorectal cancer syndromes require timely endoscopic surveillance. Methods: This study evaluated the approach...

...Xiaoxiao Yang; Cheng Zhu; Yueyue Li; Yanqing Li; Xiu-Li Zuo Introduction: The long-term risks of post-polypectomy colorectal cancer (CRC) incidence and mortality among patients with low-risk adenomas (LRAs) are unclear. This study aimed to perform a systematic review and meta-analysis of the risk...

...-onset colorectal cancer (eoCRC), defined as a colorectal cancer (CRC) in patients younger than 50 years old, shows an increasing incidence worldwide in the latest years. The role of exogenous factors associated with CRC has been largely overlooked in eoCRC. Here, we conducted a case-control study...

... of colorectal cancer (CRC). We aimed to compare the adenoma detection rate (ADR) between high-resolution white light endoscopy (WLE) alone and WLE plus dye chromoendoscopy (CE) in a cohort of LS patients. Methods: In a context of real-world data, we retrospectively enrolled 50 LS patients who had non-randomly...

...Loránd Barabás; István Hritz; Gábor István; Zsolt Tulassay; Lászloó Herszényi Background: We and others have previously shown that matrix metalloproteinases (MMPs) play a role in colorectal cancer (CRC) invasion and metastasis. However, the serum changes of various MMPs and their inhibitors (TIMPs...

...: To evaluate the uptake of screening colonoscopy among physicians as compared to the general population. Methods: Asymptomatic physicians, aged 45–67 years, at average risk for colorectal cancer (CRC), working in the participating National Health System hospitals were asked to complete a questionnaire...

...James Schneider; Michalis Koullouros; Craig Mackay; George Ramsay; Craig Parnaby; Lynn Stevenson Background: Optimal surveillance monitoring following curative resection of colorectal cancer remains unclear. Guidelines recommend computed tomography (CT)-based imaging for the initial 3 years...

... lesions extending through the mucosa and submucosa of the digestive tract [ 1 ]. Esophageal cancer Gastric cancer Colorectal cancer Endoscopy Polyps © 2018 S. Karger AG, Basel 2018 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Colorectal adenoma Colorectal cancer Fibroblast growth factor 19 Fibroblast growth factor receptor 4 Biological...

...Winesh Ramphal; Jennifer M.J. Schreinemakers; Tom C.J. Seerden; Paul D. Gobardhan Background: The association between diverticulitis and colorectal cancer (CRC) remains unclear, though both share epidemiological characteristics. The aim of this study was to investigate whether there is higher risk...

...Robert R.J. Coebergh van den Braak; Zarina S. Lalmahomed; Stefan Büttner; Bettina E. Hansen; Jan N.M. Ijzermans; on behalf of the MATCH Study Group Background/Aims: The 5-year postoperative follow-up for patients undergoing curative treatment for colorectal cancer (CRC) is labour intensive. We...

... been responsible for this favourable trend. However, other factors may have an impact on decreasing surgical trend over time. The relative risk (RR) of colorectal cancer (CRC) in UC is approximately doubled compared to background population. However, the absolute risk in general is relatively low...

...Michael Pohl; Wolff Schmiegel Background: Colorectal cancer (CRC) is the third most common cancer type in Western countries. Significant progress has been made in the last decade in the therapy of metastatic CRC (mCRC) with a median overall survival (OS) of patients exceeding 30 months...

...Georgina L. Hold The human gut microbiota plays a major role in the development and maintenance of good health. Many recent studies have attempted to define links between microbiota residents, their function and the development of colorectal cancer (CRC). Gut microbiota drive the development...

.... Cholangiocyte Cholangiocarcinoma Colorectal cancer Gallbladder carcinoma Ulcerative colitis Conversely, evidence of HGD and unresectable LGD in histologic specimens is a strong pointer to proctocolectomy. In fact, the risk of developing synchronous sites of dysplasia is higher in patients with PSC/IBD...