... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Gut microbiota Cholestasis Inflammation Bile acids Primary sclerosing cholangitis (PSC) is a chronic cholestatic disease of unknown etiology, mainly...

... was acquired from participants’ parent/legal guardian/next of kin. All study procedures were in agreement with the ethical guidelines of the 1975 Declaration of Helsinki (6th revision, 2008). Liver mass Transaminasemia Cholestasis Liver Liver biopsy A variety of liver disorders...

... of steatosis, inflammation, and hepatocyte ballooning [ 4, 5 ]. Cholestasis Metabolic Syndrome Liver steatosis Previous studies have concluded that elevation in cholestatic enzymes among NAFLD patients is a predictor for a histologically more advanced disease [ 8 ]. Another study has found...

...Shi-Ying Cai; James L. Boyer Background: The mechanism by which bile acids induce liver injury in cholestasis remains controversial. Although high levels of bile acids are toxic when applied to liver cells, the level of toxic bile acids in the liver of most cholestatic animals and patients...

... conditions. Stimulation of the receptor prevents excessive liver damage in rodent models of cholestasis, steatohepatitis, liver fibrosis and inflammation and also promotes liver regeneration. However, the activation of TGR5-dependent signalling may also trigger proliferation and apoptosis resistance...

... and ASBT, has exciting implications for the fields of virology, cholestasis and metabolism of glucose, lipid and energy, although therapeutic efficacy and long-term (side-)effects of altering the bile acid dynamics needs to be further elucidated. The authors have nothing to disclose. References...

... of these patients experience itching during the course of their disease. This symptom is also frequently observed in patients with other causes of cholestasis such as cholangiocarcinoma, inherited forms of cholestasis and intrahepatic cholestasis of pregnancy, but may accompany almost any other liver disease...

... homeostasis' clusters are strongly expressed in the liver. Furthermore, NRs from these clusters, such as farnesoid X receptor α (FXRα), pregnane X receptor (PXR) and peroxisome proliferator-activated receptors (PPARs), have been associated with the pathogenesis and the progression of cholestasis. The latter...

...Andreas E. Kremer; Ruth Bolier; Remco van Dijk; Ronald P.J. Oude Elferink; Ulrich Beuers Chronic pruritus is a burdensome feature of numerous hepatobiliary disorders such as primary biliary cirrhosis, primary sclerosing cholangitis, cholangiocarcinoma, inherited forms of cholestasis...

... cholestasis, and diagnosis is usually established by cholangiography. In symptomatic patients, median survival from presentation to death or liver transplantation is about 12 years. It is a premalignant condition, and the majority of deaths are from malignancy, particularly cholangiocarcinoma or colonic...

...Christoph Jüngst; Frank Lammert Cholestasis develops as a consequence of impaired bile formation and/or bile flow and can be classified as intra- or extrahepatic. Chronic cholestatic diseases are mostly intrahepatic with the exception of primary and secondary sclerosing cholangitis affecting intra...

... of biochemical indices of cholestasis in at least 30% of newly diagnosed cases [ 1 ]. UDCA appears to stabilize or even improve the histological findings suggestive of biliary epithelial destruction in a considerable proportion of patients at early stages (stages I and II), and some of those responding appear...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cholestasis Cholangiocellular...

...Catherine Williamson; Michele Miragoli; Siti Sheikh Abdul Kadir; Shadi Abu-Hayyeh; Georgia Papacleovoulou; Victoria Geenes; Julia Gorelik Background/Aims: Intrahepatic cholestasis of pregnancy (ICP) is complicated by spontaneous preterm labor, fetal anoxia and unexplained fetal death. We aim...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Apoptosis Autoimmunity Cholestasis Stress-induced ligands Immunology and Liver...

... on TPN are at greater risk of developing steatosis and intrahepatic cholestasis. Strategies to correct abnormalities include alteration of the caloric mix in the TPN, cyclic infusions, metronidazole, enteral nutrition and inclusion of L -glutamine in the TPN formula. Patients on long-term home parenteral...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bile duct obstruction Cholangiopancreatography Cholestasis Common bile duct diseases Drainage Follow-up studies...

... Raufman Division of Gastroenterology, John L. McClellan Memorial Veterans Hospital and University of Arkansas for Medical Sciences, Little Rock, Ark., USA Key Words Ehrlichiosis · Cholestasis · Rickettsia infection · Granulocytic ehrlichiosis, human · Monocytic ehrlichiosis, human Abstract Background...

...Waqar Qureshi Intrahepatic cholestasis is characterized by a decrease in bile flow in the absence of overt bile duct obstruction, resulting in the accumulation of bile constituents in the liver and blood. Various etiological factors have been incriminated including drugs, total parenteral nutrition...

... of Alabama at Birmingham, Ala., USA Hepatobiliary Diseases in Patients with AIDS: Focus on AIDS Cholangiopathy and Gallbladder Disease OOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO Key Words Human immunodeficiency virus Cholangitis Cholestasis Cholecystitis...