.... In the subgroup analysis, the pooled HR was 0.38 (95% CI, 0.24–0.59) for OS in H. pylori -positive patients who received surgery combined with chemotherapy. The pooled HR for disease-free survival was 0.74 (95% CI, 0.63–0.8) and 0.41 (95% CI, 0.26–0.65) in patients who received surgery combined with chemotherapy...

.... Hepatitis B reactivation Chemotherapy Immunosuppressive therapy Rituximab Although some have questioned the accuracy of the names for these phases recently, the fact that liver injury is caused by the immune response to the virus rather than a direct cytopathic effect of viral replication is useful...

... for the treatment of patients with unresectable HCC in 2007. The phase II trial performed on 137 chemotherapy-naive patients, with inoperable HCC and CP-A or -B cirrhosis treated with sorafenib (400 mg twice daily), showed a median time to tumor progression (TTP) of 5.5 months and a median OS of 9.2 months...

... Objective: A number of studies have reported reactivation of hepatitis B during intensive immunosuppressive therapy such as cases of hematological malignancy, whereas little has been reported for characteristics of reactivation triggered by chemotherapy for solid cancer. Methods: A total of 130 patients...

... complete resection of primary tumor and liver metastases. Optimal treatment of colorectal resectable liver metastases includes preoperative chemotherapy that can be administered after resection of the primary tumor and before resection of liver metastases in a ‘classical’ fashion, before combined resection...

... and chemotherapeutic options of patients with unresectable liver metastases. 23 11 2012 Chemotherapy Colorectal cancer Unresectable liver metastases © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... of chemotherapy regimen with the adjunction of antiangiogenics now allow secondary resection. Recent evidence suggests almost identical long-term survival in case of secondary downstaged lesions advocating an aggressive approach. However, these data lie on disparate and nonconsensual criteria for unresectability...

.... Mark s Hospital. London, UK Anal Cancer Current Perspectives Key Words Anal cancer Anal intraepithelial neoplasia Human papillomavirus Aetiology Surgery Radiotherapy Chemotherapy Abstract Anal cancer is uncommon accounting for only 2% of anorectal cancers. The recognition of many similarities between...

... of local control and toxicity compared to postoperative therapy. Several recent studies show that 5-FU-based chemotherapy enhances tumor response to radiotherapy and preoperative chemoradiotherapy is being increasingly used for stage II and III disease. Rectal cancer Radiotherapy Chemotherapy...

...Markus Moehler; Carl C. Schimanski; Ines Gockel; Theodor Junginger; Peter R. Galle Despite surgical R0 resections, patients with gastric cancer stage UICC II–III have a high risk of recurrence and metachronic metastases. Preliminary evidence exists that adjuvant chemotherapy or neoadjuvant chemo...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Colorectal cancer Microsatellite instability Chromosomal instability Chemotherapy Chemosensitivity Review Article Dig Dis 2002;20:73 80 The Role of Genomic Instabilities in Affecting Treatment...

... and can lead to disease stabilization. Adjuvant therapy with interferon is indicated after successful liver resection or transplantation in patients with chronic viral hepatitis, the role of interferon in other indications or in combination with chemotherapy remains to be determined. 27 3 2002...

..., chemotherapy, occurence of a carcinoma in relatives, preoperative physical condition, night sweat) were determined. In the 193 patients with palliative treatment, only ten factors (among them UICC tumor stage including the presence of metastases; data from the medical history such as physical condition, loss...

... intention. Classical end points of palliative treatment are survival, tumor response, and quality of life. A decade ago, palliative chemotherapy consisted mainly of 5-fluorouracil as the standard agent in combination with either other agents and/or radiotherapy. Only the new antineoplastic drug gemcitabine...