... to guide us into the future. Noteworthy is that the majority of the alleged PPI-refractory GERD patients do not, after careful investigations, have GERD. Based on recently published RCT data, a clinically highly relevant difference in treatment success was noted in favor of laparoscopic antireflux surgery...

.... Furthermore, observational studies have shown that PPI use is associated with a decreased incidence of neoplasia in Barrett's esophagus. In theory, successful antireflux surgery, which eliminates the reflux of both acid and bile, should be better for cancer prevention than medical therapy, which only...

... adenocarcinoma Acid inhibition Proton pump inhibitors Antireflux surgery Barrett’s esophagus (BE) is an important premalignant condition in which the squamous epithelium of the distal esophagus is replaced by columnar epithelium-containing goblet cells [ 1 ]. BE is a complication of chronic...

... DOI: 10.1159/000210103 Early-Stage Adenocarcinoma in Barrett s Esophagus: Aspects of Surgical Therapies Örs Péter Horváth Katalin Kalmár Department of Surgery, Medical Center, University of Pécs, Pécs, Hungary Key Words Barrett s esophagus Antireflux surgery Early esophageal adenocarcinoma...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Weakly acidic reflux Proton pump inhibitors Antireflux surgery Reflux inhibitors Dig Dis 2009;27:58 61 DOI: 10.1159...

... monitoring Antireflux surgery Nissen fundoplication 4 11 2008 © 1993 S. Karger AG, Basel 1993 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means...

..., instructions or products referred to in the content or advertisements. Gastroesophageal reflux disease Nissen fundoplication Laparoscopy Antireflux surgery Digestive Diseases DigDis 1996; 14:169-179 Jeffrey H. Peters Tom R. DeMeesler University of Southern California School of Medicine, Department...

... evidence exists to show that antireflux surgery is more effective than proton pump inhibition in the control of reflux-related symptoms. Side effects are burdening surgical repair, many of which do not decrease over time. Data are not consistent to show any benefit of surgery whenever health economic...

... incorporating the duodenal components in the refluxate may be warranted. In all those situations antireflux surgery can be considered indicated for the treatment of chronic GERD and thus be looked upon as complementary to medical therapy. Furthermore, some patients who have their GERD symptoms under control...

... was suppressed, most epithelium reverted back to squamous mucosa. Similar findings in human patients with Barrett’s esophagus (BE) who were treated with laser ablation were first described in 1993. While acid suppression with antireflux surgery or proton pump inhibitors (PPIs) has proven insufficient...