Development and Validation of an Endoscopic Classification of Diverticular Disease of the Colon: The DICA Classification

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy

^aGastroenterology Service, ASL BAT, Andria, ^bDivision of Gastroenterology, ‘Cristo Re' Hospital, Rome, ^cDivision of Gastroenterology, ‘Cà Foncello' Hospital, Treviso, ^dDivision of Hepatology, ‘San Camillo' Hospital, Rome, ^eDivision of Gastroenterology, ‘Campus Biomedico' University Hospital, Rome, ^fDivision of Gastroenterology, ‘San Giovanni Battista' Hospital, Turin, ^gDivision of Gastroenterology, ‘T. Maresca' Hospital, Torre del Greco, ^hDivision of Gastroenterology and Digestive Endoscopy, ‘Cattinara' Hospital, Trieste, ⁱDepartment of Internal Medicine, Digestive Endoscopy Service, ‘A. Gemelli' Hospital, Catholic University, Rome, ^jDivision of Digestive Surgical Endoscopy, ‘G.B. Grassi' Hospital, Ostia, ^kDivision of Gastroenterology, Physiopathology and Digestive Endoscopy, Bolzano Hospital, Bolzano, ^lDigestive Endoscopy Service, ‘Pierangeli' Home Care, Pescara, ^mDivision of Digestive Endoscopy, ‘Sant'Agostino Estense' Hospital, Baggiovara, ⁿDivision of Gastroenterology, ULSS 18, Rovigo, ^oDivision of Gastroenterology, ASL RMH, Albano Laziale, ^pDivision of Gastroenterology, ‘Belcolle' Hospital, Viterbo, ^qDivision of Gastroenterology, ASL3 Umbria, Foligno, ^rDivision of Digestive Endoscopy, ‘S. Maria Goretti' Hospital, Latina, ^sDivision of Gastroenterology, ‘San Martino' Hospital, Belluno, ^tDigestive Endoscopy and Nutrition Unit, ‘S. Eugenio' Hospital, Rome, ^uDivision of Gastroenterology, ‘S. Camillo de Lellis', Rieti, ^vDivision of Gastroenterology, ‘Curto' Hospital, Polla, ^wDivision of Gastroenterology and Digestive Endoscopy, ‘S. Pertini' Hospital, Rome, ^xDivision of Gastroenterology, ‘M. Sarcone' Hospital, Terlizzi, ^yDivision of Gastroenterology and Interventional Endoscopy, ‘Niguarda-Cà Granda' Hospital, Milan, ^zDivision of Gastroenterology and Digestive Endoscopy, ‘Padre Pio' Hospital, Vasto, ^aaDivision of Gastroenterology, ‘Santa Maria della Misericordia' Hospital, Udine, ^bbDivision of Gastroenterology and Digestive Endoscopy, ‘Nuovo Regina Margherita' Hospital, Rome, ^ccClinical Pharmacology and Digestive Pathophysiology Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, and ^ddDivision of Surgery, ‘P. Colombo' Hospital, ASL RMH, Velletri, Italy