Venous tumor thrombus occurs in 5-10% of patients with renal cell carcinoma. Surgical excision offers the best chance for survival, but is technically difficult. Risk of pulmonary embolism from venous thrombus or tumor thrombus is high, especially with tumors located higher in the inferior vena cava. Cardiopulmonary bypass may be used when a tumor extends above the diaphragm, but carries significant risk. We present an 86-year-old woman with a 7 cm renal mass extending into the inferior vena cava just below the confluence of the hepatic vessels. Prior to surgery she was found to have increasing pulmonary embolisms despite appropriate anticoagulation. Intraoperatively, the AngioVac aspiration system was utilized to prevent further pulmonary embolism. This is the first reported case of the use of this system during radical nephrectomy.

1.
Woodruff DY, Van Veldhuizen P, Muehlebach G, Johnson P, Williamson T, Holzbeierlein JM: The perioperative management of an inferior vena caval tumor thrombus in patients with renal cell carcinoma. Urol Oncol 2013;31:517-521.
2.
Wotkowicz C, Wszolek MF, Libertino JA: Resection of renal tumors invading the vena cava. Urol Clin North Am 2008;35:657-671.
3.
Martinez-Salamanca JI, Huang WC, Millan I, Bertini R, Bianco FJ, Carballido JA, Ciancio G, Hernández C, Herranz F, Haferkamp A, Hohenfellner M, Hu B, Koppie T, Martínez-Ballesteros C, Montorsi F, Palou J, Pontes JE, Russo P, Terrone C, Villavicencio H, Volpe A, Libertino JA: Prognostic impact of the 2009 UICC/AJCC TNM staging system for renal cell carcinoma with venous extension. Eur Urol 2011;59:120-127.
4.
Karnes RJ, Blute ML: Surgery insight: management of renal cell carcinoma with associated inferior vena cava thrombus. Nat Clin Pract Urol 2008;5:329-339.
5.
Novick AC, Streem SB, Pontes JE, Stewart BH: Stewart's Operative Urology, ed 2. Baltimore, Willimans & Wilkins, 1989.
6.
Ciancio G, Vaidya A, Savoie M, Soloway M: Management of renal cell carcinoma with level III thrombus in the inferior vena cava. J Urol 2002;168:1374-1377.
7.
Zini L, Koussa M, Haulon S, Decoene C, Fantoni JC, Biserte J, Villers A: Results of endoluminal occlusion of the inferior vena cava during radical nephrectomy and thrombectomy. Eur Urol 2008;54:778-783.
8.
Todoran TM, Sobieszczyk PS, Levy MS, Perry TE, Shook DC, Kinlay S, Davidson MJ, Eisenhauer AC: Percutaneous extraction of right atrial mass using the AngioVac aspiration system. J Vasc Interv Radiol 2011;22:1345-1347.
9.
Bissada NK, Yakout HH, Babanouri A, Elsalamony T, Fahmy W, Gunham M, Hull GW, Chaudhary UB: Long-term experience with management of renal cell carcinoma involving the inferior vena cava. Urology 2003;61:89-92.
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