... of complex tissue environments and offer a versatile alternative to traditional microfluidic systems. Summary: This review highlights recent advances in paper-based microfluidics for tissue engineering and regenerative medicine. Key applications include 3D cell culture, bioanalysis assays, and high...

... be addressed with end-to-end anastomosis, larger defects require tracheal reconstruction, a complex procedure with no universally successful replacement strategy. Tissue engineering offers a promising solution for tracheal repair, particularly focusing on regenerating its epithelium, which plays a critical...

... Biomimetic systems Drug screening Tissue engineering Three-dimensional (3D) cell culture has been a focus of research for decades, driven by the need to accurately mimic the natural cellular microenvironment in vitro [ 1‒3 ]. The potential of successful 3D cell culture to revolutionize our...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Biomedical engineering Tissue engineering Stem cell differentiation Transcription factors Vascular biology Lymphatic biology NIH The lymphatic system...

... remains a challenge in vascular tissue engineering. Current delivery methods such as direct administration of therapeutics can fail to maintain the necessary sustained release profile and often rely on supraphysiologic doses to achieve the desired therapeutic effect. By implementing a microparticle...

... interactions and blood vessel integrity, but little is known about how stromal cells regulate cadherin signaling in the vasculature. Our objective was to investigate the relationship between mechanical phenotypes of stromal cells with cadherin expression in 3D tissue engineering models of vascular growth...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 3D skin models Bovine cell culture Tissue engineering Organotypic model Skin equivalent In bovine medicine, claw lesions have been identified as the main cause...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Engineered cardiac tissue Cardiac disease models Tissue engineering Tissue chips NIH The heart is a dynamic organ...

... higher levels of osteogenesis in vivo. Finally, when incorporated as the endplate region of a larger tissue-engineered intervertebral disc replacement, HA coating did not induce mineralization in or promote cell migration out of neighboring biomaterials. Overall, these results verified tunable biomimetic...

.... It is noteworthy that the OoC market potential goes beyond pharma, with the possibility to test cosmetics, food additives, or environmental contaminants. This (micro)tissue engineering-based technology is highly multidisciplinary, combining fields such as (developmental) biology, (bio)materials, microfluidics...

... environment of the oral cavity. On the one hand, mature enamel is cell-free and, if damaged, does not regenerate. Tooth sensitivity and decay are caused by enamel loss. On the other hand, the tissue engineering approach is challenging because of the unique structure of tooth enamel. To develop an exemplary...

...Gustavo S.S. Matias; Ana C.O. Carreira; Vitória F. Batista; Rodrigo S.N. Barreto; Maria A. Miglino; Paula Fratini Decellularized scaffolds applied in tissue engineering offer improvements, supplying the elevated necessity for organs and tissues for replacement. However, obtaining a functional...

.... Oogonial stem cells Female germline stem cells DDX4 Transdifferentiation Tissue engineering The age-old doctrine in the field of female physiology stated that females of mammalian species including humans were born with a limited number of follicles and no neofolliculogenesis happened...

...Ajay Kumar Sahi; Neelima Varshney; Suruchi Poddar; Shravanya Gundu; Sanjeev Kumar Mahto Tissue engineering is a promising approach to overcome the severe worldwide shortage of healthy donor corneas. In this work, we have developed a silk-gelatin composite scaffold using electrospinning...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bioartificial organs Biomaterials Tissue engineering Biofabrication...

... relevant to axon regenerative potential in nerve repair. We found that ECM treatments on fibers enhanced the regeneration of adult axons indicating that both the physical and biochemical presentation of the fibers are essential for enhancing axon guidance and growth. Tissue engineering Nerve...

... systems to fit numerous applications due to a broad variety of properties they display upon varying the composition ratio and molecular weight of blocks. In this review, the synthesis, fundamentals, electrospinning, and tissue engineering application of block copolymers are highlighted. seeram...

... extensively investigated the use of human cadaveric tissue-engineered periosteum-allograft constructs as an approach to healing such serious orthopedic surgical situations. In this current report, human cadaveric periosteum-wrapped bone allografts and counterpart controls without periosteum were implanted...

... methods for bone repair under investigation is a tissue-engineered bone substitute. An ideal property of tissue-engineered bone substitutes is osteoinductivity, defined as the ability to stimulate primitive cells to differentiate into a bone-forming lineage. In the current study, we use...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Adipose-derived stem cells Tissue engineering Skin substitute Mesenchymal stem cells Adipose-derived stem cells...